UAMS MLT-MLS
COMPREHENSIVE EXAM
QUESTIONS AND COMPLETE
SOLUTIONS GRADED A+
Your Exam Plug
,Which antibody is most associated with delayed hemolytic transfusion reactions? - Answer: Anti-Jka
What is most associated with Anti-I? - Answer: Mycoplasma pneumonia
IgG antibodies cause ______ hemolysis from sequestration by spleen. - Answer: Extravascular
T/F: Enzyme panels will react with Duffy Antibodies (Fya or Fyb). - Answer: False
T/F: RhIG at 28 weeks can cause a mom to have a low titer anti-D. - Answer: True
What type of blood should be given if from mom to child? - Answer: Irradiated
Room temp crossmatch detects _____ errors. - Answer: ABO
Why do premature infants typically need transfusions? - Answer: Blood loss from lab tests
When phenotyping, use a positive control that is _______ positive. - Answer: Heterozygously
Why is cryoprecipitate normally used? - Answer: To replace fibrinogen
What can make an auto control positive? (Distinguish by warming, looking under scope or saline
replacement) - Answer: Rouleaux and Cold auto
Cold auto will react with _____ AHG and ___ Monospecific AHG. - Answer: Polyspecific; C3
What kind of plasma can an AB= patient be transfused with? - Answer: AB (+ or =)
_____ transfusion must be fresh, CMV =, radiated and collected with CPDA - Answer: Intrauterine
,How should intrauterine transfusions be handled? - Answer: Radiated and collected with CPDA
When is FFP used? - Answer: When PT and PTT are prolonged
At what temperature do Lewis antibodies react? - Answer: RT and sometimes 37
What type of hemolysis do Lewis antibodies cause? - Answer: In Vitro
How long are sexual partners of IV drug users differed from donating? - Answer: 1 year
+DAT can make the Rh control ___ when doing weak D test - Answer: Positive
Storage: Whole Blood - Answer: 1-6 C; 35 days
Storage: RBCs (Red cells, Packed RBCs, RBCs) - Answer: 1-6 C (CPDA- 35 days; ADSOL- 42 days)
Storage: Leukocyte- Reduced RBCs - Answer: 1-6 C (CPDA- 35 days; ADSOL- 42 days)
Storage: Washed Red Cells - Answer: 1-6 C; 24 hours
Storage: Irradiated Blood to prevent GVHD - Answer: 1-6 C; 28 days
Storage: Frozen/ Deglycerolized RBCs - Answer: -70 C for 10 years; 1-6 C for 24 hours after prepared
Storage: Random Platelets - Answer: 20-24 C; 5 days with agitation and temp check every 4 hours (4
hours after pooling)
Storage: Platelets, Apheresis (single-donor) - Answer: 20-24 C with agitation; 5 days
, Storage: Granulocytes, Apheresis - Answer: 20-24 C; 24 hours
Storage: FFP, frozen - Answer: -18 C; 1 year
Storage: FFP, thawed - Answer: 1-6 C; 24 hours
Storage: Frozen Cryoprecipitated AHF - Answer: -18 C; 1 year
Storage: Thawed Cryoprecipitated AHF - Answer: RT if used for Factor VIII; 1-6 if used for fibrinogen
Storage: Pooled Cryoprecipitated AHF - Answer: 20-24 C; 4 hours
What are whole blood transfusions used for? - Answer: Cells and volume
What are packed RBC transfusions used for? - Answer: Anemia
What are Washed RBC transfusions used for? - Answer: Allergy to plasma proteins in IgA deficiencies
What are Leuko-depleted RBC transfusions used for? - Answer: Febrile from HLA or CMV risk
What are Frozen, deglycerolized RBC transfusions used for? - Answer: Rare or autologous
What must be done to issue red cell products? - Answer: ABO, Rh and screening compatible
How are PLTs and WBCs stored? - Answer: RT
What are Leuko-reduced PLT or WBC transfusions used for? - Answer: Prevent febrile from HLA and
prevent CMV
COMPREHENSIVE EXAM
QUESTIONS AND COMPLETE
SOLUTIONS GRADED A+
Your Exam Plug
,Which antibody is most associated with delayed hemolytic transfusion reactions? - Answer: Anti-Jka
What is most associated with Anti-I? - Answer: Mycoplasma pneumonia
IgG antibodies cause ______ hemolysis from sequestration by spleen. - Answer: Extravascular
T/F: Enzyme panels will react with Duffy Antibodies (Fya or Fyb). - Answer: False
T/F: RhIG at 28 weeks can cause a mom to have a low titer anti-D. - Answer: True
What type of blood should be given if from mom to child? - Answer: Irradiated
Room temp crossmatch detects _____ errors. - Answer: ABO
Why do premature infants typically need transfusions? - Answer: Blood loss from lab tests
When phenotyping, use a positive control that is _______ positive. - Answer: Heterozygously
Why is cryoprecipitate normally used? - Answer: To replace fibrinogen
What can make an auto control positive? (Distinguish by warming, looking under scope or saline
replacement) - Answer: Rouleaux and Cold auto
Cold auto will react with _____ AHG and ___ Monospecific AHG. - Answer: Polyspecific; C3
What kind of plasma can an AB= patient be transfused with? - Answer: AB (+ or =)
_____ transfusion must be fresh, CMV =, radiated and collected with CPDA - Answer: Intrauterine
,How should intrauterine transfusions be handled? - Answer: Radiated and collected with CPDA
When is FFP used? - Answer: When PT and PTT are prolonged
At what temperature do Lewis antibodies react? - Answer: RT and sometimes 37
What type of hemolysis do Lewis antibodies cause? - Answer: In Vitro
How long are sexual partners of IV drug users differed from donating? - Answer: 1 year
+DAT can make the Rh control ___ when doing weak D test - Answer: Positive
Storage: Whole Blood - Answer: 1-6 C; 35 days
Storage: RBCs (Red cells, Packed RBCs, RBCs) - Answer: 1-6 C (CPDA- 35 days; ADSOL- 42 days)
Storage: Leukocyte- Reduced RBCs - Answer: 1-6 C (CPDA- 35 days; ADSOL- 42 days)
Storage: Washed Red Cells - Answer: 1-6 C; 24 hours
Storage: Irradiated Blood to prevent GVHD - Answer: 1-6 C; 28 days
Storage: Frozen/ Deglycerolized RBCs - Answer: -70 C for 10 years; 1-6 C for 24 hours after prepared
Storage: Random Platelets - Answer: 20-24 C; 5 days with agitation and temp check every 4 hours (4
hours after pooling)
Storage: Platelets, Apheresis (single-donor) - Answer: 20-24 C with agitation; 5 days
, Storage: Granulocytes, Apheresis - Answer: 20-24 C; 24 hours
Storage: FFP, frozen - Answer: -18 C; 1 year
Storage: FFP, thawed - Answer: 1-6 C; 24 hours
Storage: Frozen Cryoprecipitated AHF - Answer: -18 C; 1 year
Storage: Thawed Cryoprecipitated AHF - Answer: RT if used for Factor VIII; 1-6 if used for fibrinogen
Storage: Pooled Cryoprecipitated AHF - Answer: 20-24 C; 4 hours
What are whole blood transfusions used for? - Answer: Cells and volume
What are packed RBC transfusions used for? - Answer: Anemia
What are Washed RBC transfusions used for? - Answer: Allergy to plasma proteins in IgA deficiencies
What are Leuko-depleted RBC transfusions used for? - Answer: Febrile from HLA or CMV risk
What are Frozen, deglycerolized RBC transfusions used for? - Answer: Rare or autologous
What must be done to issue red cell products? - Answer: ABO, Rh and screening compatible
How are PLTs and WBCs stored? - Answer: RT
What are Leuko-reduced PLT or WBC transfusions used for? - Answer: Prevent febrile from HLA and
prevent CMV
