SUCCESS
The Wolffian duct contributes to which of the following male gonadal structures? Van
deferens
A researcher is studying a transcription factor that that is essential for the formation of the
mesonephric duct. Based on your knowledge of the developing urogenital tract, which of the
following defects would you predict that you will find in mice when a knock out mutation has
been made in this gene? Male mice will have defects in their vas deferens
Prior to the TSP you incubate Trachemys scripta turtle eggs at a temperature that produces
100% males during the TSP. This will result in which of the following? No effect on sex
determination
If there is a mutation in the male specific exon of sex-lethal that removes the stop codon what
sex would offspring be? All female
A knockout of sox9 was made using a Sf-1cre and floxed sox9 allele. What do you expect the
phenotype of XY mice to be? Female
b-catenin is necessary for ovary development. Which of the following factors are necessary for
its activation? Rspo1 and Wnt4
,A 17 year old male patient has shown up in clinic with a lack of secondary sex characteristics, a
very high BMI (obese). His testosterone levels are low. You suspect which of the following
disorders? Frolich syndrome
You have diagnosed your patient as potentially suffering from Frohlich syndrome. What would
you look for to confirm this? Hypothalamic tumor
A male patient demonstrates a complete lack of spermatozoa in his semen. This is which of the
following? Azoospermia
Which of the following gut tube derived structures result from the fusion of two separate buds
off the tube? Pancreas
A patient with Celiac disease stops eating all products containing wheat, barley, and rye. What
would you expect after several months? The patient is normal with normal villi
Which of the following structures derives from the neural crest and regulate the "fight or flight"
stress response? Sympathetic chain ganglion
Which of the following structures contains the cell bodies for the sensory neurons? Dorsal
root ganglion
What is the embryological origin of the retina? Neural plate ectoderm
,What is the correct order of bones of the middle ear, going from outside to inside? Malleus,
incus, stapes
What is the embryological origin of the cochlea and semicircular canals (inner ear)? Head
surface ectoderm
Which of the following accounts for the mechanism by which Planaria are able to be sliced into
multiple pieces and then regenerate new animals? Stem cells within each piece producing
new animals
During epimorphic regeneration in newts, what is the structure formed by dedifferentiating
tissues? blastema
You label the cartilage of a salamander by transgenesis using a GFP reporter. Then you
transplant part of the bone from this transgenic animal into a wild-type animal. After limb
amputation of this transplanted animal, you see that none of the muscle cells are green. What
do you then conclude is the most likely source of the muscle tissue in the regenerated limb?
Satellite cells residing in the muscle
Signaling between endosteal osteoblasts and hematopoietic stem cells (HSC) in the niche are
necessary for which of the following? maintenance of HSC potency and proliferation
, Production of iPS cells from adult cells replicates the potency of which of the following
embryonic tissues? Epiblast
You have found a molecule that has a 25000 dalton molecular weight. Your colleague suspects
it's a teratogen. Do you agree? Maybe
Exposure to teratogens during the fetal period of pregnancy will always result in organ damage.
False
Since DES binds to the estrogen receptor and alters the normal estrogen response how would
you class this endocrine disruptor? Trigger
Are the wings of a dragonfly analogous or homologous to those of a bat? analogous
If you placed a bead soaked in calmodulin onto the developing beak of a chick embryo, what
would you expect to see? Longer beak
Although both birds, bats, and flying dinosaurs share a common tetrapod vertebrate ancestor,
flight is thought to have arisen independently three times due to divergent allometry. You
should be focusing on studying enhancers regulating while bone if you were investigating bat
evolution? Metacarpals/phalanges
A promoter is required for the initiation of which of the following processes? Transcription