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Exam (elaborations)

3310 SAR (Exam 2) questions with correct answers 2025

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3310 SAR (Exam 2) questions with correct answers 2025

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Uploaded on
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  • 3310 sar exam 2 questions with correct answers 2

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3310 SAR (Exam 2) questions with
correct answers 2025
CAHSARH1H-HCORRECTHANSWERH-sulfonamideHmustHbeHprimary



CAHSARH2H-HCORRECTHANSWERH-groupHattachedHtoHsulfonamideHmustHbeHaromatic



CAHSARH3H-HCORRECTHANSWERH-lowerHakaHincreasesHCAHinhibitoryHactivity



CAHSARH4H-HCORRECTHANSWERH-increasedHlipidHcharacterHincreasesHCAHinhibitoryHactivity



CAHSARH5H-HCORRECTHANSWERH-NH2HincreasesHsalureticHeffectHandHdecreasesHCAHinhibitoryHeffect



thiazidesHSARH1H-HCORRECTHANSWERH-N-2HpositionHmustHbeHsmallH(CH3HorHH)



thiazidesHSARH2H-HCORRECTHANSWERH-3-
positionHRHgroupHdeterminesHpotencyHandHdurationHofHaction;HincreasedHlipophilicityHincreasesHp
otencyHandHduration



thiazidesHSARH3H-HCORRECTHANSWERH-3-4HdoubleHbondHreductionHincreasesHpotency



thiazidesHSARH4H-HCORRECTHANSWERH-alkylHgroupsHatH4,H5,HorH8HdecreaseHdiureticHeffect



thiazidesHSARH5H-HCORRECTHANSWERH-6-positionHEWGHaffectsHsulfonamideHatHposition-
7;HlowerHpKa=HmoreHionizedHthusHlessHreabsorbed



thiazidesHSARH6H-HCORRECTHANSWERH-sulfonamideHatH7-positionHmustHbeHunsubstituted
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