High-yield facts from MKSAP book
UPDATED ACTUAL Exam Questions and
CORRECT Answers
All treatment for HER2 positive breast cancer should include...? - CORRECT ANSWER -
Trastuzumab (monoclonal antibody)
Should aromatase inhibitors (anastrazole, letrozole) ever be given to premenopausal women? -
CORRECT ANSWER - NO. Aromatase inhibitors (ex: anastrozole) are exclusively for
post-menopausal women
What should lytic bone lesions be treated with? - CORRECT ANSWER - Bisphosphonates
(to decrease bone pain)
For patients with painful bone lesions, what should they be treated with? - CORRECT
ANSWER - Radiation therapy
Should women with metastatic disease receive mastectomy? - CORRECT ANSWER -
Majority of the time: NO (what's the point, the disease is already metastatic...)
Exception is if mastectomy is for local cancer control
Does pregnancy after breast ca tx increase risk of breast ca recurrence? - CORRECT
ANSWER - No
Pregnancy after breast cancer does not increase risk of breast cancer recurrence
Main side effect/complication of Tamoxifen therapy to watch out for - CORRECT
ANSWER - Endometrial cancer
,Main side effect of aromatase inhibitors (ex: anastrozole) to be wary of - CORRECT
ANSWER - Osteoporosis
Trastuzumab is used to treat HER2 positive breast cancer. What is main side effect? - CORRECT
ANSWER - Cardiomyopathy (and so women should receive TTE prior to therapy
initiation)
If fibrinogen is low, what do you order: FFP, prothrombin concentrate, or cryoprecipitate? -
CORRECT ANSWER - Cryo (it is highly concentrated with fibrinogen)
"FFP contains the same concentration of coagulation factors as plasma." True or False? -
CORRECT ANSWER - True
FFP approximates plasma
For patients who have smoked > 30 yrs and are aged 55-80, how frequently should you obtain
low-dose screening CT chest? - CORRECT ANSWER - Annually
"A solid lung nodule that has been stable for 2+ years is unlikely to be cancer." T or F? -
CORRECT ANSWER - True
Nodules stable > 2 yrs unlikely to be cancer
lung cancer + hyponatremia --> what is the dx? - CORRECT ANSWER - Small Cell Lung
Cancer
(SCLC produces peptide hormones: SIADH (causes hyponatremia) and ACTH
(hypercortisolism)
lung cancer + hypercortisolism --> what is the dx? - CORRECT ANSWER - Small Cell
Lung Cancer
, (SCLC produces peptide hormones: SIADH (causes hyponatremia) and ACTH
(hypercortisolism)
lung mass + hypercalcemia --> what is the dx? - CORRECT ANSWER - Squamous Cell
Cancer (type of Non-Small Cell Lung Cancer)
Is the risk of colorectal cancer elevated in both ulcerative colitis and crohn's disease? -
CORRECT ANSWER - Yes, it is elevated in both
Normal colon ca screening schedule - CORRECT ANSWER - Age 50-74 q10y
Colon ca screening schedule: 1st degree relative w colon ca < 60 yrs of age - CORRECT
ANSWER - Start age 40 or 10 yrs younger than age of dx
Colonoscopy q5y
Colon ca screening schedule: Ulcerative Colitis or Crohn's Disease - CORRECT
ANSWER - 8 yrs after initial dx
q1-2y
Colon ca screening schedule: Primary Sclerosing Cholangitis - CORRECT ANSWER - At
time of dx
q1-2y
If a patient's FIT test is positive for blood, what do you do? - CORRECT ANSWER - Get
full colonoscopy
UPDATED ACTUAL Exam Questions and
CORRECT Answers
All treatment for HER2 positive breast cancer should include...? - CORRECT ANSWER -
Trastuzumab (monoclonal antibody)
Should aromatase inhibitors (anastrazole, letrozole) ever be given to premenopausal women? -
CORRECT ANSWER - NO. Aromatase inhibitors (ex: anastrozole) are exclusively for
post-menopausal women
What should lytic bone lesions be treated with? - CORRECT ANSWER - Bisphosphonates
(to decrease bone pain)
For patients with painful bone lesions, what should they be treated with? - CORRECT
ANSWER - Radiation therapy
Should women with metastatic disease receive mastectomy? - CORRECT ANSWER -
Majority of the time: NO (what's the point, the disease is already metastatic...)
Exception is if mastectomy is for local cancer control
Does pregnancy after breast ca tx increase risk of breast ca recurrence? - CORRECT
ANSWER - No
Pregnancy after breast cancer does not increase risk of breast cancer recurrence
Main side effect/complication of Tamoxifen therapy to watch out for - CORRECT
ANSWER - Endometrial cancer
,Main side effect of aromatase inhibitors (ex: anastrozole) to be wary of - CORRECT
ANSWER - Osteoporosis
Trastuzumab is used to treat HER2 positive breast cancer. What is main side effect? - CORRECT
ANSWER - Cardiomyopathy (and so women should receive TTE prior to therapy
initiation)
If fibrinogen is low, what do you order: FFP, prothrombin concentrate, or cryoprecipitate? -
CORRECT ANSWER - Cryo (it is highly concentrated with fibrinogen)
"FFP contains the same concentration of coagulation factors as plasma." True or False? -
CORRECT ANSWER - True
FFP approximates plasma
For patients who have smoked > 30 yrs and are aged 55-80, how frequently should you obtain
low-dose screening CT chest? - CORRECT ANSWER - Annually
"A solid lung nodule that has been stable for 2+ years is unlikely to be cancer." T or F? -
CORRECT ANSWER - True
Nodules stable > 2 yrs unlikely to be cancer
lung cancer + hyponatremia --> what is the dx? - CORRECT ANSWER - Small Cell Lung
Cancer
(SCLC produces peptide hormones: SIADH (causes hyponatremia) and ACTH
(hypercortisolism)
lung cancer + hypercortisolism --> what is the dx? - CORRECT ANSWER - Small Cell
Lung Cancer
, (SCLC produces peptide hormones: SIADH (causes hyponatremia) and ACTH
(hypercortisolism)
lung mass + hypercalcemia --> what is the dx? - CORRECT ANSWER - Squamous Cell
Cancer (type of Non-Small Cell Lung Cancer)
Is the risk of colorectal cancer elevated in both ulcerative colitis and crohn's disease? -
CORRECT ANSWER - Yes, it is elevated in both
Normal colon ca screening schedule - CORRECT ANSWER - Age 50-74 q10y
Colon ca screening schedule: 1st degree relative w colon ca < 60 yrs of age - CORRECT
ANSWER - Start age 40 or 10 yrs younger than age of dx
Colonoscopy q5y
Colon ca screening schedule: Ulcerative Colitis or Crohn's Disease - CORRECT
ANSWER - 8 yrs after initial dx
q1-2y
Colon ca screening schedule: Primary Sclerosing Cholangitis - CORRECT ANSWER - At
time of dx
q1-2y
If a patient's FIT test is positive for blood, what do you do? - CORRECT ANSWER - Get
full colonoscopy
