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Test Bank - Karch Focus on Nursing Pharmacology 9th Edition by Rebecca Tucker Chapters 1 - 59

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Test Bank - Karch Focus on Nursing Pharmacology 9th Edition by Rebecca Tucker Chapters 1 - 59 Chapter 01- Introduction to Drugs Chapter 02- Drugs and the Body Chapter 03- Toxic Effects of Drugs Chapter 04- The Nursing Process in Drug Therapy and Patient Safety Chapter 05- Dosage Calculations Chapter 06- Challenges to Effective Drug Therapy Chapter 07- Introduction to Cell Physiology Chapter 08- Anti-infective Agents Chapter 09- Antibiotics Chapter 10- Antiviral Agents Chapter 11- Antifungal Agents Chapter 12- Antiprotozoal Agents Chapter 13- Anthelmintic Agents Chapter 14- Antineoplastic Agents Chapter 15- Introduction to the Immune Response and InflammationChapter 16- Anti-inflammatory, Antiarthritis, and Related Agents Chapter 17- Immune Modulators Chapter 18- Vaccines and Sera Chapter 19- Introduction to Nerves and the Nervous SystemChapter 20- Anxiolytic and Hypnotic Agents Chapter 21- Antidepressant Agents Chapter 22- Psychotherapeutic AgentsChapter 23- Antiseizure Agents Chapter 24- Antiparkinsonism Agents Chapter 25- Muscle Relaxants Chapter 26- Narcotics, Narcotic Antagonists, and Antimigraine Agents Chapter 27- General and Local Anesthetic Agents Chapter 28- Neuromuscular Junction Blocking Agents Chapter 29- Introduction to the Autonomic Nervous SystemChapter 30- Adrenergic Agonists Chapter 31- Adrenergic Antagonists Chapter 32- Cholinergic Agonists Chapter 33- Anticholinergic Agents Chapter 34- Introduction to the Endocrine SystemChapter 35- Hypothalamic and Pituitary Agents Chapter 36- Adrenocortical Agents Chapter 37- Thyroid and Parathyroid Agents Chapter 38- Agents to Control Blood Glucose Levels Chapter 39- Introduction to the Reproductive System Chapter 40- Drugs Affecting the Female Reproductive System Chapter 41- Drugs Affecting the Male Reproductive System Chapter 42- Introduction to the Cardiovascular System Chapter 43- Drugs Affecting Blood Pressure Chapter 44- Agents for Treating Heart Failure Chapter 45- Antiarrhythmic Agents Chapter 46- Antianginal Agents Chapter 47- Lipid-Lowering Agents Chapter 48- Drugs Affecting Blood Coagulation Chapter 49- Drugs Used to Treat Anemias Chapter 50- Introduction to the Renal System Chapter 51- Diuretic Agents Chapter 52- Drugs Affecting the Urinary Tract and the Bladder Chapter 53- Introduction to the Respiratory System Chapter 54- Drugs Acting on the Upper Respiratory Tract Chapter 55- Drugs Acting on the Lower Respiratory Tract Chapter 56- Introduction to the Gastrointestinal System Chapter 57- Drugs Affecting Gastrointestinal Secretions Chapter 58- Drugs Affecting Gastrointestinal Motility Chapter 59- Antiemetic Agents

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Test Bank - Karch Focus on Nursing Pharmacology
9th Edition by Rebecca Tucker
Chapters 1 - 59

, Table of Contents
Chapter 01- Introduction to Drugs
Chapter 02- Drugs and the Body
Chapter 03- Toxic Effects of Drugs
Chapter 04- The Nursing Process in Drug Therapy and Patient Safety
Chapter 05- Dosage Calculations
Chapter 06- Challenges to Effective Drug Therapy
Chapter 07- Introduction to Cell Physiology
Chapter 08- Anti-infective Agents
Chapter 09- Antibiotics
Chapter 10- Antiviral Agents
Chapter 11- Antifungal Agents
Chapter 12- Antiprotozoal Agents
Chapter 13- Anthelmintic Agents
Chapter 14- Antineoplastic Agents
Chapter 15- Introduction to the Immune Response and
InflammationChapter 16- Anti-inflammatory, Antiarthritis, and
Related Agents Chapter 17- Immune Modulators
Chapter 18- Vaccines and Sera
Chapter 19- Introduction to Nerves and the Nervous
SystemChapter 20- Anxiolytic and Hypnotic Agents
Chapter 21- Antidepressant Agents
Chapter 22- Psychotherapeutic
AgentsChapter 23- Antiseizure Agents
Chapter 24- Antiparkinsonism Agents
Chapter 25- Muscle Relaxants
Chapter 26- Narcotics, Narcotic Antagonists, and Antimigraine Agents
Chapter 27- General and Local Anesthetic Agents
Chapter 28- Neuromuscular Junction Blocking Agents
Chapter 29- Introduction to the Autonomic Nervous
SystemChapter 30- Adrenergic Agonists
Chapter 31- Adrenergic Antagonists
Chapter 32- Cholinergic Agonists
Chapter 33- Anticholinergic Agents
Chapter 34- Introduction to the Endocrine
SystemChapter 35- Hypothalamic and Pituitary
Agents Chapter 36- Adrenocortical Agents
Chapter 37- Thyroid and Parathyroid Agents
Chapter 38- Agents to Control Blood Glucose Levels
Chapter 39- Introduction to the Reproductive
System
Chapter 40- Drugs Affecting the Female Reproductive System
Chapter 41- Drugs Affecting the Male Reproductive System
Chapter 42- Introduction to the Cardiovascular System
Chapter 43- Drugs Affecting Blood Pressure
Chapter 44- Agents for Treating Heart Failure
Chapter 45- Antiarrhythmic Agents
Chapter 46- Antianginal Agents
Chapter 47- Lipid-Lowering Agents
Chapter 48- Drugs Affecting Blood Coagulation
Chapter 49- Drugs Used to Treat Anemias
Chapter 50- Introduction to the Renal System
Chapter 51- Diuretic Agents
Chapter 52- Drugs Affecting the Urinary Tract and the Bladder
Chapter 53- Introduction to the Respiratory System
Chapter 54- Drugs Acting on the Upper Respiratory Tract
Chapter 55- Drugs Acting on the Lower Respiratory Tract
Chapter 56- Introduction to the Gastrointestinal System
Chapter 57- Drugs Affecting Gastrointestinal Secretions
Chapter 58- Drugs Affecting Gastrointestinal Motility
Chapter 59- Antiemetic Agents

, Chapter 1: Introduction to Drugs




Cognitive Level: Application
Difficulty: Moderate
Integrated Process: Nursing process
1.A nurse working in radiology administers iodine to a patient who is having a
computerized axial tomography (CAT) scan. A nurse working on an oncology unit
administers chemotherapy to patients who have cancer. At the Public Health
Department, a nurse administers a measles-mumps-rubella (MMR) vaccine to a
14-month-old child as a routine immunization. Which branch of pharmacology
best describes the actions of all three nurses?
A) Pharmacoeconomics
B) Pharmacotherapeutics
C) Pharmacodynamics
D) Pharmacokinetics
ANSWER: B
Response:
Pharmacology is the study of the biologic effects of chemicals. Nurses are involved
with clinical pharmacology or pharmacotherapeutics, which is a branch of
pharmacology that deals with the uses of drugs to treat, prevent, and diagnose
disease. The nurse working in radiology is administering a drug to help diagnose a
disease. The nurse working on an oncology unit is administering a drug to help treat
adisease. Pharmacoeconomics includes any costs involved in drug therapy.
Pharmacodynamics involves how a drug affects the body, and pharmacokinetics is
how the body acts on the drug.




Cognitive Level: Comprehension
Difficulty: Easy
Integrated Process: Nursing process


2.A physician has ordered intramuscular injections of morphine, a narcotic, every 4
hours as needed for pain for a motor vehicle accident victim. The nurse is aware that
there is a high abuse potential for this drug; therefore, morphine is categorized as a:
A) Schedule I drug

,B) Schedule II drug
C) Schedule III drug
D) Schedule IV drug
ANSWER: B
Response:
Narcotics such as morphine are considered schedule II drugs because of the high
abuse potential with severe dependence liability. Schedule I drugs have high abuse
potential and no accepted medical use. Schedule III drugs have a lesser abuse
potential than schedule II drugs and an accepted medical use. Schedule IV drugs
havelow abuse potential and limited dependence liability.




Cognitive Level: Comprehension
Difficulty: Easy
Integrated Process: Communication and documentation
3.A nurse working for a drug company is involved in phase III drug evaluation studies.
Which of the following might the nurse be responsible for during this stage of drug
development?

, Chapter 1: Introduction to Drugs




A) Working with animals who are given experimental drugs
B) Monitoring drug effects in patients who are selected to participate in a
study,who have the disease that the drug is meant to treat
C) Collecting records of symptoms that participants experience while taking
adrug and determining whether they are caused by the disease or the
drug
D) Informing healthy, young volunteer participants of possible risks that
couldoccur from taking an experimental drug
ANSWER: C
Response:
Phase III studies involve use of a drug in a vast clinical market where patients are
asked to record any symptoms they experience while taking the drugs. Nurses may
beresponsible for helping collect and analyze the information to be shared with the
Food and Drug Administration (FDA). Use of animals in drug testing is done in the
preclinical trials. A select group of patients who are involved in phase II studies
participate in studies where the participants have the disease the drug is intended
to treat. These patients are monitored closely for drug effects. Phase I studies
involve healthy human volunteers who are usually paid for their participation.
Nurses may observe for adverse effects and toxicity.




Cognitive Level: Comprehension
Difficulty: Moderate
Integrated Process: Nursing Process


4.Which of the following concepts is considered when generic drugs are substituted
forbrand-name drugs?
A) Bioavailability
B) Critical concentration
C) Distribution
D) Half-life
ANSWER: A
Response:

, Bioavailability is the portion of a dose of a drug that reaches the systemic circulation
and is available to act on body cells. Binders used in a generic drug may not be the
same as those used in the brand-name drug. Therefore, the way the body breaks
downand uses the drug may differ, which may eliminate a substitution. Critical
concentration is the amount of a drug that is needed to cause a therapeutic effect.
Distribution is the phase of pharmacokinetics that involves the movement of a drug
tothe body's tissues. A drug's half-life is the time it takes for the amount of drug to
decrease to one-half of the peak level.




Cognitive Level: Analysis
Difficulty: Difficult
Integrated Process: Teaching/learning
5.A nurse is teaching her patient about the use of over-the-counter (OTC) drugs.
Whichof the following statements best informs the patient about their safe use?
A) “OTC drugs are products that are available without prescription for
self-treatment of minor complaints.”
B) “OTC drugs are considered medications and should be reported on a
drughistory.”

, Chapter t1: tIntroduction tto
tDrugs




C) “OTC tdrugs twere tapproved tas tprescription tdrugs tbut tlater twere tfound tto
tbetsafe twithout tthe tneed tfor ta tprescription.”

D) “OTC tdrugs tneed tto tbe ttaken twith tcaution. tThey tcan tmask tthe tsigns
tand tsymptoms tof tan tunderlying tdisease tand tinterfere twith

tprescription tdrug ttherapy.”

ANSWER: D
Response:
OTC tdrugs tare tconsidered tmedications tand tshould tbe treported. tOTC tdrugs tare
tavailable twithout ta tprescription, talthough tsome twere tfirst tapproved tas

tprescription tdrugs. tThe tmost timportant tteaching tshould trelate tto ttheir tsafe tuse

tand tthat tOTC tdrugstcan tmask tsymptoms tof tdisease tand tinterfere twith tprescribed

tdrugs.




Cognitive tLevel:
tKnowledgetDifficulty: tEasy

Integrated tProcess: t Nursing tProcess
6.Which tof tthe tfollowing tlegislative tacts tallowed tthe tFood tand tDrug
tAdministrationt(FDA) tto ttighten tcontrol tover tthe tquality tof tdrugs tand trequired

tthat tsafety tand tefficacy tstandards tbe testablished?

A) Pure tFood tand tDrug tAct tof t1906
B) Federal tFood, tDrug, tand tCosmetic tAct tof t1938
C) Durham tHumphrey tAmendment tof t1951
D) Kefauver-Harris tAct tof t1962
ANSWER: D
Response:
The tKefauver-Harris tAct twas tthe tresult tof tthe tuse tof tthe t1960s tdrug tthalidomide
t(Thalomid). tThe tpublic tconcern tled tto tthe tlegislation tthat tgave tthe tFDA tregulatory

tcontrol tover ttesting tand tevaluating tof tdrugs tand tallowed tit tto tset tstandards tfor

tefficacy tand tsafety. tThe tPure tFood tand tDrug tAct trequired tlabeling tto teliminate

tfalsetclaims. tThe tFederal tFood, tDrug, tand tCosmetic tAct tgave tthe tFDA tthe tpower tto

tenforce tstandards tfor ttesting tdrug ttoxicity tand tmonitoring tlabeling. tThe tDurham-

, tHumphrey tAmendment tenforced tprescriptions tfor tdistribution.




Cognitive tLevel:
t ApplicationtDifficulty: tModerate

Integrated tProcess: t Teaching/learning
7.A tnurse tis tinstructing ta tpregnant tpatient tconcerning tthe tpotential trisk tto ther
tfetustfrom ta tpregnancy tcategory tB tdrug. tThe tnurse twould tinform tthe tpatient

tthat:

A) “Adequate tstudies tin tpregnant twomen thave tdemonstrated tthere tis tno trisk
tto tthetfetus.”

B) “Animal tstudies thave tnot tdemonstrated ta trisk tto tthe tfetus tbut tthere thave
tbeentno tadequate tstudies tin tpregnant twomen.”

C) “Animal tstudies thave tshown tan tadverse teffect ton tthe tfetus tbut tthere
tare tnotadequate tstudies tin tpregnant twomen.”

D) “There tis tevidence tof thuman tfetal trisk tbut tthe tpotential tbenefits tfrom tuse tof
tthetdrug tmay tbe tacceptable tdespite tpotential trisks.”

ANSWER: B
Response:
Category tB tindicates tthat tanimal tstudies thave tnot tdemonstrated ta trisk tto tthe tfetus tbut

, Chapter t1: tIntroduction tto
tDrugs




there thave tbeen tno tadequate tstudies tin tpregnant twomen. tHowever, tthere thave
tnot tbeen tadequate tstudies tin tpregnant twomen tto tdemonstrate trisk tto ta tfetus

tduring tthe tfirst ttrimester tof tpregnancy tand tno tevidence tof trisk tin tlater ttrimesters.

tCategory tA tindicates tthat tadequate tstudies tin tpregnant twomen thave tnot

tdemonstrated ta trisk tto tthetfetus tin tthe tfirst ttrimester tor tin tlater ttrimesters.

tCategory tC tindicates tthat tanimal tstudies thave tshown tan tadverse teffect ton tthe

tfetus tbut tthere thave tbeen tno tadequate tstudies tin thumans. tCategory tD treveals

tevidence tof thuman tfetal trisk, tbut tthe tpotential tbenefits tfrom tthe tuse tof tthe tdrugs

tin tpregnant twomen tmay toutweigh tthe trisks.




Cognitive tLevel:
t AnalysistDifficulty: t Difficult
Integrated tProcess: t Teaching/learning
8. Discharge tplanning tfor tpatients tleaving tthe thospital tshould tinclude tinstructions
tontthe tuse tof tover-the-counter t(OTC) tdrugs. tWhich tcomment tby tthe tpatient

twould tdemonstrate ta tgood tunderstanding tof tOTC tdrugs?

A) “OTC tdrugs tare talways tsafe tand twill tnot tcause tbad teffects.”
B) “OTC tdrugs thave tbeen taround tfor tyears tand thave tnot tbeen ttested tby tthe
tFoodtand tDrug tAdministration t(FDA).”

C) “OTC tdrugs tare tdifferent tfrom tany tdrugs tavailable tby tprescription tand
tcosttless.”

D) “OTC tdrugs tare tthought tto tbe tsafe twhen ttaken tas
tdirected.”tANSWER: D
Response:
OTC tdrugs tare tdrugs tthat thave tbeen tdetermined tto tbe tsafe twhen ttaken tas
tdirected.tThey tmay thave toriginally tbeen tprescription tdrugs tthat twere ttested tby

tthe tFDA tor tthey tmay thave tbeen tgrandfathered tin twhen tthe tFDA tlaws tchanged.

tOTC teducationtshould talways tbe tincluded tas ta tpart tof tthe thospital tdischarge

tinstructions.




Cognitive tLevel:

, tComprehensiontDifficulty:

tModerate

Integrated tProcess: t Teaching/Learning
9. Which tof tthe tfollowing twould tbe tthe tbest tsource tof tdrug tinformation tfor ta tnurse?
A) Drug tFacts tand tComparisons tbook
B) A tnurse's tdrug tguide
C) A tdrug tpackage tinsert
D) The tPhysician's tDrug tReference t(PDR)
ANSWER: B
Response:
The tmost tuser-friendly tdrug tsource tfor ta tnurse tis ta tnurse's tdrug tguidebook. tA
tguidetprovides tnursing timplications tand tpatient tteaching tpoints tthat tare tmost

tuseful tto tnurses. tThe tDrug tFacts tand tComparisons tbook tprovides ta twide trange

tof tdrug tinformation tbut tis thard tto tmanipulate tand tis tvery texpensive. tA tpackage

tinsert tcontains tall tof tthe tchemical tand tdrug tcompany tresearch tinformation

tabout ta tdrug; thowever, tthe tinformation tcan tbe tdifficult tto tunderstand tand tthe

tprint tis tvery tsmall. tThe tPDR tis theavily tcross-referenced tand tdifficult tto tuse.




Cognitive tLevel: t Comprehension

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