x
Introduction to Genetic Analysis
x x x
Anthony J.F. Griffiths, John Doebley, Catherine Peichel, and David A.
x x x x x x x x x
Wassarman
x
12th Edition
x
,Table of Contents
x x
Chapter x 01 x The x Genetics x Revolution 1
Chapter x 02 x Single x Gene x Inheritance 6
Chapter x 03 x Independent x Assortment x of x Genes 26
Chapter x 04 x Mapping x Eukaryote x Chromosomes x by x Recombination 43
Chapter x 05 x Gene x Interaction 63
Chapter x 06 x The x Genetics x of x Bacteria x and x Their x Viruses 84
Chapter x 07 x DNA x Structure x and x Replication 104
Chapter x 08 x RNA x Transcription x Processing x and x Decay 117
Chapter x 09 x Proteins x and x Their x Synthesis 130
Chapter x 10 x Gene x Isolation x and x Manipulation 141
Chapter x 11 x Regulation x of x Gene x Expression x in x Bacteria x and x Their x Viruses 160
Chapter x 12 x Regulation x of x Gene x Expression x in x Eukaryotes 175
Chapter x 13 x The x Genetic x Control x of x Development 184
Chapter x 14 x Genomes x and x Genomics 192
Chapter x 15 x DNA x Damage x Repair x and x Recombination 197
Chapter x 16 x The x Dynamic x Genome x Transposable x Elements 216
Chapter x 17 x Large x Scale x Chromosomal x Changes 225
Chapter x 18 x Population x Genetics 243
Chapter x 19 x The x Inheritance x of x Complex x Traits 258
Chapter x 20 x Evolution x of x Genes x and x Traits 270
, Test x Bank x - x Introduction x to x Genetic x Analysis, x 12th x Edition x (Griffiths, x 2021)
Chapter x 01: x The x Genetics x Revolution
1. The x early x 1900s x was x an x important x period x for x genetics x due x to x which x of x the x following x major x events?
a. the x rediscovery x of x Gregor x Mendel's x scientific x findings
b. Watson x and x Crick x solving x the x structure x of x DNA
c. Walter xSutton x and x Theodore x Boveri x hypothesizing x that x chromosomes x are x the x hereditary x elements
d. the xrediscovery xof xGregor xMendel's xscientific xfindings xand xWalter xSutton xand xTheodore
x Boveri x hypothesizing x that x chromosomes x are x the x hereditary x elements
e. All x of x the x answer x options x are x correct.
ANSWER: x x e
2. A x sample x of x normal x double-stranded x DNA x was x found x to x have x a x guanine x content x of x 18%. x What
x is x the xexpected xproportion xof xadenine?
a. 9%
b. 32%
c. 36%
d. 68%
e. 82%
ANSWER: x x b
3. In x one x strand x of x DNA, x the x nucleotide x sequence x is x 5'-ATGC-3'. x The x complementary x sequence
x in x the xother xstrand xmust xbe
a. 3'-ATGC-5'.
b. 3'-TACG-5'.
c. 5'-ATCG-3'.
d. 5'-CGTA-3'.
e. 5'-TACG-3'.
ANSWER: x x b
4. How xmany x different x DNA x molecules x that x are x eight-nucleotide-pairs x long x are x theoretically x possible?
a. 24
b. 32
c. 64
d. 256
e. 65,536
ANSWER: x x e
5. Which x of x the x following x is/are x TRUE x about x genes?
a. Genes x are x located x on x chromosomes.
b. Genes x come x in x variants x known x as x alleles.
c. Genes x usually x encode x protein x products.
d. All x of x the x answer x options x are x correct.
e. None x of x the x answer x options x is x correct.
ANSWER: x x d
1 x| x P x a x g
x e
, Test x Bank x - x Introduction x to x Genetic x Analysis, x 12th x Edition x (Griffiths, x 2021)
6. Wild x cats x (Felis x silvestris) x and x common x mice x (Mus x musculus) x are x diploid. x In x wild x cats, x 2n
x = x 38, xwhile x in x common x mice, x 2n x = x 40. x Based x on x this x information, x we x can x conclude x that x wild-
cat x cells x have
a. less x DNA x than x common-mouse x cells.
b. smaller xgenomes x than x common-mouse x cells.
c. fewer xDNA x molecules x than x common-mouse x cells.
d. fewer xgenes x than x common-mouse x cells.
e. fewer x sets x of xchromosomes x than x common-mouse x cells.
ANSWER: x x c
7. Which x of x the x following x is x a x component x of x DNA?
a. alanine
b. arginine
c. cysteine
d. guanine
e. tyrosine
ANSWER: x x d
8. Which x of x the x following x is/are x TRUE x of x the x DNA x structure x solved x by x Watson x and x Crick?
a. It x is x a x double-helical x structure.
b. Sugar–phosphate x backbone x is x always x toward x the x outside x of x the x DNA.
c. There x are x two x hydrogen x bonds x between x A x and x T x and x three x hydrogen x bonds x between x C x and x G.
d. There x are x four x types x of x nitrogenous x bases.
e. All x of x the x answer x options x are x correct.
ANSWER: x x e
9. Which x of x the x following x is x a x CORRECT x representation x of x the x central x dogma?
a. RNA x → x DNA x → x protein
b. protein x → x DNA x → x RNA
c. DNA x → x RNA x → x protein
d. DNA x → x protein x → x DNA
e. None x of x the x answer x options x is x correct.
ANSWER: x x c
10. You x have x come x across x a x dog x (named x Cindy) x that x does x not x have x a x tail. x Interestingly, x all x the
x puppies xproduced x by x this x dog x don't x have x a x tail. x If x the x lack x of x tail x is x caused x by x a x genetic
x mutation, x where x has x this xmutation xmost xlikely xtaken xplace?
a. in x Cindy's x gametes
b. in x the x cells x that x should x normally x have x given x rise x to x Cindy's x tail
c. in x the x cells x that x should x normally x have x given x rise x to x Cindy's x and x her x puppies' x tails
d. in x all x of x Cindy's x cells x (including x her x gametes)
e. in x a x gamete x of x one x of x Cindy's x parents
ANSWER: x x a
11. Which x of x the x following x features x makes x a x species x suitable x as x a x model x organism?
2 x| x P x a x g
x e