USMLE Step 2 CS Minicases ALL
2025/2026 Exam Questions and Answers
| 100% Solved
HEADACHE
Key History - 🧠 ANSWER ✔✔*Onset*: acute vs. chronic
*Location*: u/l vs. b/l
*Quality*: dull, stabbing
*Intensity*: worst HOL?
*Duration*
*Timing*: disturb sleep?
*Neuro sx*: paresthesias, visual changes, weakness, ataxia, photophobia,
dizziness, auras, neck stiffness
*Other sx*: N/V, jaw claudication, recent trauma, dental surgery, sinusitis sx
*Exacerbating/alleviating factors*
COPYRIGHT©NINJANERD 2025/2026. YEAR PUBLISHED 2025. COMPANY REGISTRATION NUMBER: 619652435. TERMS OF USE. PRIVACY
1
STATEMENT. ALL RIGHTS RESERVED
,*Patient hx
Family hx*
HEADACHE
Physical Exam - 🧠 ANSWER ✔✔Vital signs
Inspection and palpation of head
ENT inspection
Neuro exam
Fundoscopic exam
26 yo M presents with severe right
temporal headaches associated with
ipsilateral rhinorrhea, eye tearing, and
redness. Episodes have occurred at the
same time every night for the past week
and last for 45 minutes. - 🧠 ANSWER ✔✔*Cluster headache*
Migraine
COPYRIGHT©NINJANERD 2025/2026. YEAR PUBLISHED 2025. COMPANY REGISTRATION NUMBER: 619652435. TERMS OF USE. PRIVACY
2
STATEMENT. ALL RIGHTS RESERVED
,Tension headache
Sinusitis
Pseudotumor cerebri
Trigeminal neuralgia
Intracranial neoplasm
CBC
ESR
CT—head
MRI—brain
LP
21 yo F presents with several episodes of
throbbing left temporal pain that lasts
for 2-3 hours. Prior to its onset, she sees
fl ashes of light in her right visual fi eld
and feels weakness and numbness on the
COPYRIGHT©NINJANERD 2025/2026. YEAR PUBLISHED 2025. COMPANY REGISTRATION NUMBER: 619652435. TERMS OF USE. PRIVACY
3
STATEMENT. ALL RIGHTS RESERVED
, right side of her body for a few minutes.
Headaches are often associated with
nausea and vomiting. She has a family
history of migraine. - 🧠 ANSWER ✔✔*Migraine (complicated)*
Tension headache
Cluster headache
Pseudotumor cerebri
Trigeminal neuralgia
CNS vasculitis
Partial seizure
Intracranial neoplasm
CBC
ESR
CT—head
MRI—brain
COPYRIGHT©NINJANERD 2025/2026. YEAR PUBLISHED 2025. COMPANY REGISTRATION NUMBER: 619652435. TERMS OF USE. PRIVACY
4
STATEMENT. ALL RIGHTS RESERVED
2025/2026 Exam Questions and Answers
| 100% Solved
HEADACHE
Key History - 🧠 ANSWER ✔✔*Onset*: acute vs. chronic
*Location*: u/l vs. b/l
*Quality*: dull, stabbing
*Intensity*: worst HOL?
*Duration*
*Timing*: disturb sleep?
*Neuro sx*: paresthesias, visual changes, weakness, ataxia, photophobia,
dizziness, auras, neck stiffness
*Other sx*: N/V, jaw claudication, recent trauma, dental surgery, sinusitis sx
*Exacerbating/alleviating factors*
COPYRIGHT©NINJANERD 2025/2026. YEAR PUBLISHED 2025. COMPANY REGISTRATION NUMBER: 619652435. TERMS OF USE. PRIVACY
1
STATEMENT. ALL RIGHTS RESERVED
,*Patient hx
Family hx*
HEADACHE
Physical Exam - 🧠 ANSWER ✔✔Vital signs
Inspection and palpation of head
ENT inspection
Neuro exam
Fundoscopic exam
26 yo M presents with severe right
temporal headaches associated with
ipsilateral rhinorrhea, eye tearing, and
redness. Episodes have occurred at the
same time every night for the past week
and last for 45 minutes. - 🧠 ANSWER ✔✔*Cluster headache*
Migraine
COPYRIGHT©NINJANERD 2025/2026. YEAR PUBLISHED 2025. COMPANY REGISTRATION NUMBER: 619652435. TERMS OF USE. PRIVACY
2
STATEMENT. ALL RIGHTS RESERVED
,Tension headache
Sinusitis
Pseudotumor cerebri
Trigeminal neuralgia
Intracranial neoplasm
CBC
ESR
CT—head
MRI—brain
LP
21 yo F presents with several episodes of
throbbing left temporal pain that lasts
for 2-3 hours. Prior to its onset, she sees
fl ashes of light in her right visual fi eld
and feels weakness and numbness on the
COPYRIGHT©NINJANERD 2025/2026. YEAR PUBLISHED 2025. COMPANY REGISTRATION NUMBER: 619652435. TERMS OF USE. PRIVACY
3
STATEMENT. ALL RIGHTS RESERVED
, right side of her body for a few minutes.
Headaches are often associated with
nausea and vomiting. She has a family
history of migraine. - 🧠 ANSWER ✔✔*Migraine (complicated)*
Tension headache
Cluster headache
Pseudotumor cerebri
Trigeminal neuralgia
CNS vasculitis
Partial seizure
Intracranial neoplasm
CBC
ESR
CT—head
MRI—brain
COPYRIGHT©NINJANERD 2025/2026. YEAR PUBLISHED 2025. COMPANY REGISTRATION NUMBER: 619652435. TERMS OF USE. PRIVACY
4
STATEMENT. ALL RIGHTS RESERVED
