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Type 1 Hypersensitivity Reaction - ✔✔- anaphylaxis
- establish airway, epi, benadryl, steroids
Type 2 Hypersensitivity Reation - ✔✔- cytotoxic response
- give pre meds, run drug slower
Type 3 Hypersensitivity Reaction - ✔✔- immune complex response
- pre meds, give slower
Type 4 Hypersensitivity Reaction - ✔✔- delayed response
- give pre meds, run slower
DIC definition - ✔✔- clotting factor is triggered in response to infection, cancer, etc
- concurrent bleeding and clotting
DIC physical exam - ✔✔- sudden small bruising, dizzy, SOB
- change in LOC, petechiae, decreased breath and heart sounds, decreased BP
DIC labs - ✔✔- increased D Dimer and FDP titers
- decreased platelets, fibrinogen, antithrombin and plasminogen
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, DIC treatments - ✔✔- IV fluids and blood products for volume loss
- oxygen and replace clotting factors
- prevent clotting with heparin
SIADH - ✔✔syndrome of antidiuretic hormone secretion
- excess ADH is released and causes excess water to be held and not excreted
- decreased sodium levels, decreased concentration, intracellular edema, brain edema,
concentrated urine
SIADH history - ✔✔- most commonly seen in lung cx
- ask about fluid and sodium intake daily
SIADH physical exam - ✔✔confusion, fluid retention, weight gain, seizure from low
sodium
SIADH treatment - ✔✔- fluid restriction to correct hyponatremia
- IV fluids with high sodium content
- frequent neuro checks and seizure precautions
- cardiac monitoring
Sepsis - ✔✔- fever above 100.4, pulse greater than 9-, resp greater than 20, WBC greater
than 12
- only need 2 symptoms
Sepsis treatment - ✔✔blood cultures, antibiotics, IV fluids, oxygen
Septic Shock warm phase - ✔✔- initial phase
- dilation in veins and arteries, confusion, increased HR and RR
- initially normal BP
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