NURS 617 Exam 3 - Questions With Easy-to-Follow Solutions

NURS 617 Exam 3 - Questions With Easy-to-Follow
Solutions

Not for use in type 1 diabetes Correct Answer - - Meglitinides
- Sodium glucose co-transporter 2 inhibitors
- Alpha glucosidase inhibitors
- DPP-4 inhibitors
- Second generation sulfonylureas
- Metformin

Can use in Type 1 and type 2 Correct Answer - - pramlintide

Reduce in patients with renal insufficiency Correct Answer - - DPP-4
inhibitors
- Tetracyclines
- Terbinafine

Reduced doses in hepatic insufficiency Correct Answer - - Caspofungin

Monitor LFT Correct Answer - - Propylthiouracil (antithyroid)
- Methimazole (antithyroid)
- Rifampin (abx)
- Tetracyclines (abx)
- Isoniazid (abx)
- Pyrazinamide (abx)
- Terbinafine (antifungal)

Aerobic gram negative abx Correct Answer - - Aminoglycosides

Gram positive Correct Answer - -Pencillin G&V
-Vancomycin
- Oxazolidinones
- First generation cephalosporins

Gram positive & gram negative Correct Answer - - Aminopenicillins
- Tetracyclines

,- 2nd generation cephalosporins
- Clindamycin
- Rifampin.
- sometimes Penicillin G&V

Gram negative Correct Answer - - 3rd generation cephalosporins
- sometimes aminopenicllins (H. Influenza, E. Coli, salmonella, shigella)

Primarily gram positive but also gram negative Correct Answer - -
Penicillin G

Ineffective against anaerobes Correct Answer - - Fluoroquinolones

Not active against aerobes Correct Answer - - Metronidazole

Cytochrome P-450 enzyme inhibition Correct Answer - -
Streptogramins
- Macrolides

Effective against C. Diff Correct Answer - - Metronidazole

Requires serum peak and trough levels Correct Answer - -
Aminoglycosides

Monitor serum levels and PT/INR Correct Answer - - Fluoroquinolones

Avoid alcohol Correct Answer - - Metronidazole
- 3rd generation cephalosporins

May cause antibiotic associated colitis Correct Answer - - Second
generation cephalosporins

Covers everything Correct Answer - - Fluoroquinolones

only administered orally for abx associated colitis Correct Answer -
Vanc

Especially noted for its fight on meningitis Correct Answer - - Rifampin

, Gram positive and gram negative and some nontraditional (chlymydia, lyme)
Correct Answer - - Macrolides

Effectively kills dormant cells Correct Answer - - Pyrazinamide

Monotherapy for Prevention of TB Correct Answer - - Isoniazid

Blocked by cations Correct Answer - - Tetracyclines
- Fluoroquinolones

Monitor uric acid levels Correct Answer - Pyrazinamide

Administered on empty stomach Correct Answer - - Azithromycin

Only effective in active dividing fungal organisms Correct Answer - -
Azole drugs

Can use prophylactically in AIDS Correct Answer - - Clotrimazole
- Fluconazole

Low gastric pH is required for absorption Correct Answer - -
Itraconazole

Can inhibit hepatic drug metabolizing enzymes and increase the concentration
of CCB and drugs that prolong QT interval Correct Answer - -
Itraconazole

May worsen heart failure Correct Answer - - Itraconazole

Effective against rare fungal infections (invasive aspergillosis) Correct
Answer - - Voriconazole

may cause prolongation of the QT interval Correct Answer - -
Voriconazole

Active against most Candida species Correct Answer - - Micafungin

Higher dose for esophageal candida Correct Answer - - Micafungin