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1. Which of the following changes is least likely C) A mutation that
to arise from a point mutation in a changes the
regulatory region of a gene? subcellular localization
A)A mutation that changes the time on an of a protein
organism's life during which a protein is
expressed
B) A mutation that eliminates the production of
a pro- tein in a specific cell type
C)A mutation that changes the subcellular
localization of a protein
D) A mutation that increases the level of
protein pro- duction in a cell
2. Which one statement below is true? C. A pseudogene is
A. To develop a new function, evolution very similar to a
essentially functional
builds from first principles, designing from scratch, to gene but
cannot be ex-
find the best possible solution. pressed because of muta
B. Nearly every instance of DNA duplication leads to a tions.
new functional gene.
C. A pseudogene is very similar to a
functional gene but cannot be expressed
because of mutations.
D. Most genes in vertebrates are unique, and
only a few genes are members of multigene
families.
E. Horizontal transfer is very rare and thus
has had little influence on the genomes of
bacteria.
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3. Which of the following is not a mechanism of A. purifying selection
genetic variation?
A. purifying selection
B. mutation within the regulatory DNA of a
gene
C. gene duplication and divergence
D. exon shuffling
E. mutation within the coding sequence of a
gene
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4. What is the most general term for a change in a single A. point
mutation
nucleotide pair?
A. point mutation
B. frameshift mutation
C. missense mutation
D. nonsense mutation
E. neutral mutation
5. Determine whether the following statement is
true or True false: In sexually reproducing
organisms, only muta- tions that occur in the
germ line are passed along to progeny.
6. Which of these statements is consistent with the infor- A. Mutation A
is heritable
mation presented in the figure? generated
A. Mutation A is heritable to offspring primarily by
because the mutation took place in the which
germ line. process?
B. Mutation A is heritable to offspring A. sexual
because the mutation took place in a reproductio
n
somatic cell.
B. replication
C. Mutation B is heritable to offspring
of
because the mutation took place in the chromosom
germ line. e ends
D. All of the above are correct. C. DNA
E. None of the above are correct. replication
and repair
7. It is thought that gene duplications are D. homologo
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s recombination to ottspring because th
E. transcription mutation took place in the
germ line.
D. homologous recombi-
nation
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