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BIO 1414 Chapter 21 Lecture Notes

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This is a comprehensive and detailed note on Chapter 21; viruses for Bio 1404. An Essential Study Resource just for YOU!!









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Uploaded on
April 2, 2025
Number of pages
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Written in
2019/2020
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Lecture notes
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Ch. 21 Viruses

Virus= nucleic acid surrounded by a protein coat

Viruses are not cells!

Viral Genomes, Capsids, and Envelopes

 Viral genomes may consist of either
o Double or single-stranded DNA
o Double or single-stranded RNA
 A virus can be a DNA virus or RNA virus depending on its nucleic acid
 Capsid= protein shell that encloses the viral genome
o Capsids are built from capsomeres
 Virus= infectious particle consisting of genes that are packaged into a protein coat
 Viruses lead a “borrowed life”
o Exist in a form between a life form and chemicals
 There is no evidence as to where or how they came into existence
o This is because there is no fossil record

Viral Envelope

 Some viruses can invade their hosts by use of a membranous envelope
o These are called viral envelopes
 Viral envelopes are made from the host cells membrane
o They contain both viral and host cell molecules
 The molecules that they take from the host include phospholipids, membrane proteins
 They also have viral glycoproteins
 A host that can be invaded is decided by the proteins on the surface of both the virus and the
host
 Plant viruses- most have RNA genome and helical capsid
 Bacteriophages- viruses that infect bacteria
o Have the most complex
o Elongated capsid head that holds their DNA
o A protein tail piece attaches the phage to the host and injects the phage DNA inside

Viruses Replicate Only in Host Cells

 Viruses are obligate intracellular parasites
o This is because they can only replicate within a host cell
 Every virus has a host range
o A host range is a limited number of host cells that a virus can infect
o The host range is determined by the proteins on the surface of the host and the virus

General Features of Viral Replicative Cycles
 First, the viral genome enters the host cell and the cell begins to make viral proteins
 The virus uses the hosts enzymes, ribosomes, tRNAs, amino acids, ATP, and other molecules

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