NR 601 MIDTERM EXAM QUESTIONS
AND ANSWERS
All of the following statements about drug absorption are false except ✅✅ANSW-Underlying
chronic disease has little impact on drug absorption
The cytochrome p system involves enzymes that are generally: ✅✅ANSW-Inhibited or induced by
drugs
A statement not shown to be true about pharmacodynamic changes with aging is ✅✅ANSW-
Decreased sensitivity to oral anticoagulants
The major impact of the physiological changes that occur w/aging is: ✅✅ANSW-Reduced
physiological reserve, reduced homeostatic mechanisms, impaired immunological respons
The strongest evidence regarding normal physiological aging is available through ✅✅ANSW-
Longitudinal studies
Pharmacokinetic changes with aging is reflective of ✅✅ANSW-What the body does to the drug
All of the following statements are true about drug distribution in the elderly except ✅✅ANSW-
Drugs distributed in water have a lower concentration
Men have faster and more efficient biotransformation of drugs and this is thought to be due to:
✅✅ANSW-Testosterone
Atypical presentation of disease in elderly is reflected by all of the following exept ✅✅ANSW-MI
with CP and diaphoresis
Polypharmacy is best described as ✅✅ANSW-Even a single med if there is not a clear indication
for its use
,What is the major difference between varicose veins and atherosclerosis ✅✅ANSW-Vessels that
are affected
Patient has poorly controlled HTN for >10 years. Indicate the most likely position of his PMI
✅✅ANSW-5th ICS left of MCL
43 year old Hispanic male has audible diastolic murmur best hard at the mitral point. No audible
click. He has been monitored for 2 years. What is the most likely murmur ✅✅ANSW-Mitral
Stenosis
The following are true statements about bipolar disorders in older adults except ✅✅ANSW-
Bipolar disorder is the most commonly diagnosed psychiatric disorder in older adults.
The caregiver for an older adult with cognitive impairment is concerned about the individuals
seeming disinterest in eating. Which suggestion does the NP offer based upon a known effect of
dementia on a clients nutrition ✅✅ANSW-Establish a routine of when and where the individual
will have their meals.
An older man has a hx of medication therapy for hypertension. Which intervention does the nurse
practitioner implement when the client reports that, I've fallen twice in 5 weeks. ✅✅ANSW-
Orthostatic blood pressures
In the elderly population, the fastest growing group is the age range ✅✅ANSW-85 years or older
Which statement correctly describes normal changes of aging ✅✅ANSW-Individual variations are
enormous at every age and in every part of the body
Compared with acute pain, persistent chronic pain requires in the nurse practitioner to
✅✅ANSW-Educate the patient to the benefit of specific lifestyle changes
When considering Erikson's developmental stages, the task for later life is referred to as
✅✅ANSW-Ego integrity
What is the method of action of anticholinergics ✅✅ANSW-Block the effect of acetylcholine on
muscarinic type 3 receptors resulting in bronchodilation
, What is the method of action of beta agonists ✅✅ANSW-Stimulates beta-2 adrenergic receptors,
increasing cyclic AMP, resulting in relaxing airways
What is tuberculosis ✅✅ANSW-Chronic, necrotizing infection caused by slow-growing acid fast
bacillus (mycobacterium tuberculosis). Most common cause of death related to infectious disease
worldwise
What is aortic regurgitation? ✅✅ANSW-Retrograde blood flow through an incompetent aortic
valve into left ventricle during ventricular diastole
What is aortic stenosis ✅✅ANSW-abnormal narrowing of the aortic valve
What is mitral stenosis ✅✅ANSW-Abnormal narrowing of the mitral valve orifice
What is mitral regurgitation ✅✅ANSW-Retrograde blood flow during systole from the left
ventricle into the left atrium through incompetent mitral valve
What is mitral valve prolapse? ✅✅ANSW-Mitral regurgitation associated with bulging of one or
both mitral valve leaflets into the left atrium during ventricular systole
What happens in valvular regurgitation ✅✅ANSW-Portion of the ejected blood leaks back into
the upstream cardiac chamber
What happens in valvular stenosis ✅✅ANSW-Usually results in elevated pressures in the
chamber upstream from the stenosis
What is the purpose of functional assessment of the elderly ✅✅ANSW-Discovers the ability to
care for themselves on a daily basis
How should HTN be managed ✅✅ANSW-Stage 2 and up should be given consideration for pharm
treatment. Others can wait for lifestyle modification.
AND ANSWERS
All of the following statements about drug absorption are false except ✅✅ANSW-Underlying
chronic disease has little impact on drug absorption
The cytochrome p system involves enzymes that are generally: ✅✅ANSW-Inhibited or induced by
drugs
A statement not shown to be true about pharmacodynamic changes with aging is ✅✅ANSW-
Decreased sensitivity to oral anticoagulants
The major impact of the physiological changes that occur w/aging is: ✅✅ANSW-Reduced
physiological reserve, reduced homeostatic mechanisms, impaired immunological respons
The strongest evidence regarding normal physiological aging is available through ✅✅ANSW-
Longitudinal studies
Pharmacokinetic changes with aging is reflective of ✅✅ANSW-What the body does to the drug
All of the following statements are true about drug distribution in the elderly except ✅✅ANSW-
Drugs distributed in water have a lower concentration
Men have faster and more efficient biotransformation of drugs and this is thought to be due to:
✅✅ANSW-Testosterone
Atypical presentation of disease in elderly is reflected by all of the following exept ✅✅ANSW-MI
with CP and diaphoresis
Polypharmacy is best described as ✅✅ANSW-Even a single med if there is not a clear indication
for its use
,What is the major difference between varicose veins and atherosclerosis ✅✅ANSW-Vessels that
are affected
Patient has poorly controlled HTN for >10 years. Indicate the most likely position of his PMI
✅✅ANSW-5th ICS left of MCL
43 year old Hispanic male has audible diastolic murmur best hard at the mitral point. No audible
click. He has been monitored for 2 years. What is the most likely murmur ✅✅ANSW-Mitral
Stenosis
The following are true statements about bipolar disorders in older adults except ✅✅ANSW-
Bipolar disorder is the most commonly diagnosed psychiatric disorder in older adults.
The caregiver for an older adult with cognitive impairment is concerned about the individuals
seeming disinterest in eating. Which suggestion does the NP offer based upon a known effect of
dementia on a clients nutrition ✅✅ANSW-Establish a routine of when and where the individual
will have their meals.
An older man has a hx of medication therapy for hypertension. Which intervention does the nurse
practitioner implement when the client reports that, I've fallen twice in 5 weeks. ✅✅ANSW-
Orthostatic blood pressures
In the elderly population, the fastest growing group is the age range ✅✅ANSW-85 years or older
Which statement correctly describes normal changes of aging ✅✅ANSW-Individual variations are
enormous at every age and in every part of the body
Compared with acute pain, persistent chronic pain requires in the nurse practitioner to
✅✅ANSW-Educate the patient to the benefit of specific lifestyle changes
When considering Erikson's developmental stages, the task for later life is referred to as
✅✅ANSW-Ego integrity
What is the method of action of anticholinergics ✅✅ANSW-Block the effect of acetylcholine on
muscarinic type 3 receptors resulting in bronchodilation
, What is the method of action of beta agonists ✅✅ANSW-Stimulates beta-2 adrenergic receptors,
increasing cyclic AMP, resulting in relaxing airways
What is tuberculosis ✅✅ANSW-Chronic, necrotizing infection caused by slow-growing acid fast
bacillus (mycobacterium tuberculosis). Most common cause of death related to infectious disease
worldwise
What is aortic regurgitation? ✅✅ANSW-Retrograde blood flow through an incompetent aortic
valve into left ventricle during ventricular diastole
What is aortic stenosis ✅✅ANSW-abnormal narrowing of the aortic valve
What is mitral stenosis ✅✅ANSW-Abnormal narrowing of the mitral valve orifice
What is mitral regurgitation ✅✅ANSW-Retrograde blood flow during systole from the left
ventricle into the left atrium through incompetent mitral valve
What is mitral valve prolapse? ✅✅ANSW-Mitral regurgitation associated with bulging of one or
both mitral valve leaflets into the left atrium during ventricular systole
What happens in valvular regurgitation ✅✅ANSW-Portion of the ejected blood leaks back into
the upstream cardiac chamber
What happens in valvular stenosis ✅✅ANSW-Usually results in elevated pressures in the
chamber upstream from the stenosis
What is the purpose of functional assessment of the elderly ✅✅ANSW-Discovers the ability to
care for themselves on a daily basis
How should HTN be managed ✅✅ANSW-Stage 2 and up should be given consideration for pharm
treatment. Others can wait for lifestyle modification.
