Apex - Respiratory Pathophysiology 107 complete solutions graded A+.

Apex - Respiratory Pathophysiology 107
complete solutions graded A+.
Apex - Respiratory Pathophysiology 107
complete solutions graded A+.
Chemicals that contribute to increased airway resistance include: (Select 3)

a. Vasoactive intestinal peptide

b. Cyclic adenosine monophosphate

c. Leukotrienes

d. Nitric oxide

e. Phospholipase C

f. Inositol triphosphate - ANSWER c, e, f



What chemicals are associated with bronchodilation? - ANSWER Adenylate cyclase, cAMP, nitric oxide,
cGMP, VIP



What chemicals are associated with bronchoconstriction? - ANSWER Phospholipase C, IP3



Beta agonists - ANSWER -ol



Anticholinergics - ANSWER Atropine, glyco, ipratropium



Cromolyn - ANSWER mast cell stabilizer



Methylxanthines - ANSWER Theophylline



Methylxanthine MOA - ANSWER PDE inhibitor (increases cAMP)



Which of the respiratory medications require a blood level to monitor side effects? - ANSWER
Theophylline

, Apex - Respiratory Pathophysiology 107
complete solutions graded A+.

Theophylline - Cp >20 mcg/ml - ANSWER N/v, diarrhea, HA, disrupted sleep



Theophylline - Cp >30 mcg/ml - ANSWER Seizures, tachydysrhythmias, CHF



Which PFT is MOST sensitive indicator of small airway disease? - ANSWER FEF 25-75



FEV1 - normal value - ANSWER 80% predicted value



FVC - normal value (males, females) - ANSWER 4.8, 3.7



FEV1/FVC ratio - ANSWER 75-80%



FEF 25-75% - normal value - ANSWER 100 +/- 25% predicted value



Max voluntary ventilation - normal value (males, females) - ANSWER 140-180, 80-120



Which PFT is the best test of endurance? - ANSWER Max voluntary ventilation



Diffusing capacity - normal value - ANSWER 17-25 ml/min/mmhg



All of the following are independent risk factors for postop pulm complications EXCEPT:

a. CHF

b. asthma

c. age >65 years

d. COPD - ANSWER b