CNPR EXAM Q&A
T/F Between 3 and 7 percent of hospital admissions in the US are estimated to be
for treatment of adverse drug reactions. - Answer-True
Which statement is true about the universal scale for quantifying the severity of an
adverse drug reaction. - Answer-Such a scale does not exist yet.
Why is noncompliance a serious public health concern? - Answer-It increases the
cost of medical care
Which of the following is eligible for patent protections under US regulations? -
Answer-All
The drug itself
The method of delivering and releasing the drug into the bloodstream
The way the drug is made
T/F Drug's trade names are often unrelated to their intended use. - Answer-True
Like foods and household products, generic drugs are usually lower quality than the
brand name drugs for which they are marketed as equivalents. - Answer-False
Legally, bioequivalence of different versions of a drug can vary by up to ________. -
Answer-20%
Which of the following statements about biologistics is incorrect? - Answer-They do
not cause immune responses.
T/F Large molecule products are developed and manufactured by a chemical
process. - Answer-False
What are drugs that attract or bind to cell receptors in order to mimic or enhance
activities by endogenous chemical messengers? - Answer-Agonists
Which term denotes how an API works in the body? - Answer-Mechanism for action.
What cements the active and inert components together to maintain cohesive
portions? - Answer-Binders
What does the medical abbreviation BID denote? - Answer-Twice daily
What is the medical abbreviation for as needed? - Answer-PRN
Which components might cause patient's different reactions to a brand name and
generic drugs? - Answer-Differences in inactive ingredients.
T/F All cells have a nucleus? - Answer-False
Which of the following affects drug response? - Answer-All
,Patient's genetic makeup, age, body size, and use of other drugs and dietary
supplements.
The patient's other conditions or diseases
Whether or not the patient take the drug properly
T/F Drug reactions are predictable because they do not occur after a person has
been previously exposed to the drug one or more times without any allergic
reactions. - Answer-False
What is the main difference between a blinded and double blinded study? - Answer-
Neither the study staff nor the participants know which subjects are in the
experimental group.
What does asymptomatic mean? - Answer-not exhibiting signs or symptoms
Which term denotes the study of bodily functions (as opposed to structures)? -
Answer-Physiology
T/F In its broadest definition, a drug is any substance that produces a physical or
psychological change in the body. - Answer-True
How does the Federal Food, Drug, and Cosmetic Act (FFDCA) define a drug? -
Answer-Any substance intended for the use in diagnosis, cure, mitigation, treatment
or prevention of a disease, or a substance other than food intended to affect the
structure or function of the body.
Which statement about vitamins is correct? - Answer-
T/F: ADME testing measures the rate at which the body absorbs the drug, distributes
it to the organs necessary to produce the desired effect, metabolizes it into waste
material and then excretes it from the body. - Answer-True
ADME testing is primarily used in what field? - Answer-Pharmacokinetics
Which statement about placebo is correct? - Answer-Placebo effects can lead to
withdrawal symptoms.
T/F On average, only about 5 of 4000 drugs studied in the laboratory are eventually
studied in people. - Answer-True
Which statement is true about drugs taken sublingually? - Answer-Sublingual drugs
are absorbed directly and almost immediately into the bloodstream.
What are the 7 rights of drug administration? - Answer-1. The right patient
2. The right drug
3. The right dose
4. The right route
5. The right time
6. The right technique
7. The right documentation
, T/F Pro-drugs are administered in an active form, which is metabolized into an
inactive form. - Answer-False
The kidney of an 85-year-old person excretes drugs only _____ as efficiently as that
of a 35-year-old person. - Answer-50%
T/F The normal age-related decrease in kidney function can help doctors determine
an appropriate dosage based solely on a person's age. - Answer-True
What differentiates a caplet from a tablet? - Answer-Caplets are shaped like
capsules and have film coatings to aid in swallowing.
Where will you find the legend: "Caution: Federal law prohibits dispensing without a
prescription? - Answer-On the label of all prescription drugs.
What happens in slow acetylators? - Answer-Drugs that are metabolized by N-acetyl
transferase tend to reach higher blood levels and remain in the body longer.
About what percent of people in the US are slow acetylators? - Answer-50%
Which of the following statement about drug-drug interactions is incorrect? - Answer-
Drug-drug interactions are always harmful.
T/F: Smoking decreases the effectiveness of some drugs. - Answer-True
Which of the following statements about dietary supplements in incorrect? - Answer-
Dietary supplements are not drugs, interactions with drugs is not a concern.
Which statement is correct about an ideal drug or magic bullet? - Answer-It does not
exist.
It would be aimed directly at the disease site.
It would not harm healthy tissues.
Which statement accurately differentiates resistance from tolerance? - Answer-
Tolerance refers to a person's diminished response to a drug after repeated use,
while resistance applies to microorganisms or cancel cells abilities to withstand drug
affects.
What is a typical relationship between a drug's site of administration and site of
action? - Answer-They are usually somewhat removed from each other.
What is Cmax - Answer-The peak plasma concentration on a measuring curve.
Which of the following is not a main concept in clinical pharmacology? - Answer-
Pharmacoprocesses does not exist
Which of the following is not a route of drug administration? - Answer-Transfugal
How are intradermal drugs delivered? - Answer-By injecting under the skin.
T/F Between 3 and 7 percent of hospital admissions in the US are estimated to be
for treatment of adverse drug reactions. - Answer-True
Which statement is true about the universal scale for quantifying the severity of an
adverse drug reaction. - Answer-Such a scale does not exist yet.
Why is noncompliance a serious public health concern? - Answer-It increases the
cost of medical care
Which of the following is eligible for patent protections under US regulations? -
Answer-All
The drug itself
The method of delivering and releasing the drug into the bloodstream
The way the drug is made
T/F Drug's trade names are often unrelated to their intended use. - Answer-True
Like foods and household products, generic drugs are usually lower quality than the
brand name drugs for which they are marketed as equivalents. - Answer-False
Legally, bioequivalence of different versions of a drug can vary by up to ________. -
Answer-20%
Which of the following statements about biologistics is incorrect? - Answer-They do
not cause immune responses.
T/F Large molecule products are developed and manufactured by a chemical
process. - Answer-False
What are drugs that attract or bind to cell receptors in order to mimic or enhance
activities by endogenous chemical messengers? - Answer-Agonists
Which term denotes how an API works in the body? - Answer-Mechanism for action.
What cements the active and inert components together to maintain cohesive
portions? - Answer-Binders
What does the medical abbreviation BID denote? - Answer-Twice daily
What is the medical abbreviation for as needed? - Answer-PRN
Which components might cause patient's different reactions to a brand name and
generic drugs? - Answer-Differences in inactive ingredients.
T/F All cells have a nucleus? - Answer-False
Which of the following affects drug response? - Answer-All
,Patient's genetic makeup, age, body size, and use of other drugs and dietary
supplements.
The patient's other conditions or diseases
Whether or not the patient take the drug properly
T/F Drug reactions are predictable because they do not occur after a person has
been previously exposed to the drug one or more times without any allergic
reactions. - Answer-False
What is the main difference between a blinded and double blinded study? - Answer-
Neither the study staff nor the participants know which subjects are in the
experimental group.
What does asymptomatic mean? - Answer-not exhibiting signs or symptoms
Which term denotes the study of bodily functions (as opposed to structures)? -
Answer-Physiology
T/F In its broadest definition, a drug is any substance that produces a physical or
psychological change in the body. - Answer-True
How does the Federal Food, Drug, and Cosmetic Act (FFDCA) define a drug? -
Answer-Any substance intended for the use in diagnosis, cure, mitigation, treatment
or prevention of a disease, or a substance other than food intended to affect the
structure or function of the body.
Which statement about vitamins is correct? - Answer-
T/F: ADME testing measures the rate at which the body absorbs the drug, distributes
it to the organs necessary to produce the desired effect, metabolizes it into waste
material and then excretes it from the body. - Answer-True
ADME testing is primarily used in what field? - Answer-Pharmacokinetics
Which statement about placebo is correct? - Answer-Placebo effects can lead to
withdrawal symptoms.
T/F On average, only about 5 of 4000 drugs studied in the laboratory are eventually
studied in people. - Answer-True
Which statement is true about drugs taken sublingually? - Answer-Sublingual drugs
are absorbed directly and almost immediately into the bloodstream.
What are the 7 rights of drug administration? - Answer-1. The right patient
2. The right drug
3. The right dose
4. The right route
5. The right time
6. The right technique
7. The right documentation
, T/F Pro-drugs are administered in an active form, which is metabolized into an
inactive form. - Answer-False
The kidney of an 85-year-old person excretes drugs only _____ as efficiently as that
of a 35-year-old person. - Answer-50%
T/F The normal age-related decrease in kidney function can help doctors determine
an appropriate dosage based solely on a person's age. - Answer-True
What differentiates a caplet from a tablet? - Answer-Caplets are shaped like
capsules and have film coatings to aid in swallowing.
Where will you find the legend: "Caution: Federal law prohibits dispensing without a
prescription? - Answer-On the label of all prescription drugs.
What happens in slow acetylators? - Answer-Drugs that are metabolized by N-acetyl
transferase tend to reach higher blood levels and remain in the body longer.
About what percent of people in the US are slow acetylators? - Answer-50%
Which of the following statement about drug-drug interactions is incorrect? - Answer-
Drug-drug interactions are always harmful.
T/F: Smoking decreases the effectiveness of some drugs. - Answer-True
Which of the following statements about dietary supplements in incorrect? - Answer-
Dietary supplements are not drugs, interactions with drugs is not a concern.
Which statement is correct about an ideal drug or magic bullet? - Answer-It does not
exist.
It would be aimed directly at the disease site.
It would not harm healthy tissues.
Which statement accurately differentiates resistance from tolerance? - Answer-
Tolerance refers to a person's diminished response to a drug after repeated use,
while resistance applies to microorganisms or cancel cells abilities to withstand drug
affects.
What is a typical relationship between a drug's site of administration and site of
action? - Answer-They are usually somewhat removed from each other.
What is Cmax - Answer-The peak plasma concentration on a measuring curve.
Which of the following is not a main concept in clinical pharmacology? - Answer-
Pharmacoprocesses does not exist
Which of the following is not a route of drug administration? - Answer-Transfugal
How are intradermal drugs delivered? - Answer-By injecting under the skin.
