CNPR EXAM QUESTIONS WITH
CORRECT ANSWERS
What field is ADME testing used in primarily? - Answer-Pharmacokinetics.
Placebo effects can lead to withdrawal symptoms. (T/F) - Answer-True
On average, only about 5 of 4,000 drugs studied in laboratory are eventually studied
in people. (T/F) - Answer-True
Sublingual drugs are absorbed directly and almost immediately into the bloodstream.
(T/F) - Answer-True
What are 3 of the 7 rights of drug administration? - Answer-The right patient, the
right drug, the right dose.
Pro-drugs are administered in active form, which is metabolized into an inactive
form. (T/F) - Answer-False - Pro-drugs are administered in an inactive form, which is
metabolized into an active form; the resulting metabolites produce the desired
therapeutic effects
The kidney of an 85-year old person excretes drugs only ______ as efficiently as
that of a 35-year old person. - Answer-Around 50%
The normal age-related decrease in kidney function can help doctors determine an
appropriate dosage based solely on a person's age. (T/F) - Answer-True - The
normal age-related decrease in kidney function can help doctors determine an
appropriate dosage based solely on a person's age. However, appropriate dosage
can be determined more accurately by determining how well the kidneys are
functioning.
What differentiates a caplet from a tablet? - Answer-Caplets are shaped like
capsules and have film coatings to aid in swallowing.
Where will you find the legend, "Caution: Federal Law prohibits dispensing without a
prescription."? - Answer-On the label of all prescription drugs.
What happens in slow acetylators? - Answer-Drugs that are metabolized by N-acetyl
transferase tend to reach higher blood levels and remain the body longer.
About _______ of the people in the U.S. are slow acetylators. - Answer-50%
Drug-drug interactions are always harmful. (T/F) - Answer-False - The effects of
drugs given during the same time period are sometime beneficial but more often are
unwanted and harmful
,Smoking decreases the effectiveness of some drugs. (T/F) - Answer-True -
Chemicals in cigarette smoke can increase the activity of some live enzymes. As a
result, smoking decreases the effectiveness of some drugs.
Because dietary supplements are not drugs, interactions with drugs are not a
concern. (T/F) - Answer-False - Dietary supplement-drug interactions are changes in
a drug's effects caused by a dietary supplement taken during the same time period.
They are regulated as foods, but may interact with prescription or OTC drugs.
Ehrlich stated that an ideal drug (magic bullet) does not exist, would be aimed
precisely at a disease site, and would not harm healthy tissues. (T/F) - Answer-True
What is the difference between resistance and tolerance? - Answer-Tolerance refers
to a person's diminished response to a drug after repeated use, while resistance
applies to microorganism's or cancer cell's abilities to withstand drug effects.
Between 3% and 7% of hospital admissions in the U.S. are estimated to be for
treatment of adverse drug reactions. (T/F) - Answer-True
Which of the following would classify as Payers - Employers, patients, pharmacists,
or physicians? - Answer-Employers. - Some third party payers include the insurance
company, the employer, managed care organization, or the US government
(Medicaid and Medicare)
How would you define ethical pharmaceutical companies? - Answer-Ones that
research and develop novel drugs. - Research-based companies are the leading-
edge innovators. They develop branded drugs that are sufficiently novel to be
protected by patent from imitators. These firms are also known as ethical
pharmaceutical companies.
One of the most disappointing results of the pharmaceutical Industry's continued
investment in R&D is the few new drugs being approved and in development. (T/F) -
Answer-False - One of the most significant results of the pharmaceutical Industry's
continued investment in R&D is the large number of new drugs approved and in
development.
Thanks to modern medicines, how long are people newly diagnosed with HIV
expected to live? - Answer-Another 50 years.
How much has the average American lifespan increased since 1890? - Answer-
Almost 30 years. Since 1950 it has increased 10 years, from 68.2 to 78.7. Since
2009, it has risen 1.9 years for males and 1.6 years for females
What is a treatment group? - Answer-A group of patients assigned to receive a
specified treatment.
What is the main difference between a blinded and a double-blinded study? -
Answer-In a double blind study, neither the study staff nor the study participants
know which subjects are in the experimental group and which are in the control
group.
, What does asymptomatic mean? - Answer-Not exhibiting signs or symptoms.
What term denotes the study of bodily functions (as opposed to structures)? -
Answer-Physiology.
In its broadest definition, a drug is any substance that produces a physical or
psychological change in the body. (T/F) - Answer-True
How does the Federal Food, Drug and Cosmetic Act (FFDCA) define a drug? -
Answer-Any substance intended for use in the diagnosis, cure, mitigation, treatment,
or prevention of disease, or a substance other than food intended to affect the
structure or function of the body.
Most of the body's required vitamins must be taken from outside the body. (T/F) -
Answer-True
ADME testing measures the rate at which the body absorbs the drug, distributes it to
the organs necessary to produce the desired effect, metabolizes it into waste
material, and then excretes it from the body. (T/F) - Answer-True
There is no universal scale for quantifying the severity of an adverse drug reaction.
(T/F) - Answer-True - There is no universal scale for describing or measuring the
severity of an adverse drug reaction. Assessment is largely subjective. Reactions
can be described as mild, moderate, or severe.
Why is noncompliance a serious public health concern? - Answer-It increases the
cost of medical care.
Name 3 items available for which patent protection is available under U.S.
regulations. - Answer-The drug itself, the method of delivering and releasing the drug
into the bloodstream, and the way the drug is made.
Drugs' trade names are often unrelated to their intended use. (T/F) - Answer-False -
Trade names often suggest a characteristic of the drug
Like foods and household products, generic drugs are usually lower quality than the
brand name drugs for which they are marketed as equivalents. (T/F) - Answer-False
- Most generic drugs, although usually less expensive, are generally as effective and
of the same quality as the brand name drug
Legally, bioequivalence of different versions of a drug can vary by up to _____
percent. - Answer-20 - However, actual differences are typically only about 3.5% on
average and rarely exceed 10%
Biologics do not cause immune responses. (T/F) - Answer-False - Most, but not all
biologics (such as vaccines) work by triggering an immune response (One major
exception is blood and blood products).
CORRECT ANSWERS
What field is ADME testing used in primarily? - Answer-Pharmacokinetics.
Placebo effects can lead to withdrawal symptoms. (T/F) - Answer-True
On average, only about 5 of 4,000 drugs studied in laboratory are eventually studied
in people. (T/F) - Answer-True
Sublingual drugs are absorbed directly and almost immediately into the bloodstream.
(T/F) - Answer-True
What are 3 of the 7 rights of drug administration? - Answer-The right patient, the
right drug, the right dose.
Pro-drugs are administered in active form, which is metabolized into an inactive
form. (T/F) - Answer-False - Pro-drugs are administered in an inactive form, which is
metabolized into an active form; the resulting metabolites produce the desired
therapeutic effects
The kidney of an 85-year old person excretes drugs only ______ as efficiently as
that of a 35-year old person. - Answer-Around 50%
The normal age-related decrease in kidney function can help doctors determine an
appropriate dosage based solely on a person's age. (T/F) - Answer-True - The
normal age-related decrease in kidney function can help doctors determine an
appropriate dosage based solely on a person's age. However, appropriate dosage
can be determined more accurately by determining how well the kidneys are
functioning.
What differentiates a caplet from a tablet? - Answer-Caplets are shaped like
capsules and have film coatings to aid in swallowing.
Where will you find the legend, "Caution: Federal Law prohibits dispensing without a
prescription."? - Answer-On the label of all prescription drugs.
What happens in slow acetylators? - Answer-Drugs that are metabolized by N-acetyl
transferase tend to reach higher blood levels and remain the body longer.
About _______ of the people in the U.S. are slow acetylators. - Answer-50%
Drug-drug interactions are always harmful. (T/F) - Answer-False - The effects of
drugs given during the same time period are sometime beneficial but more often are
unwanted and harmful
,Smoking decreases the effectiveness of some drugs. (T/F) - Answer-True -
Chemicals in cigarette smoke can increase the activity of some live enzymes. As a
result, smoking decreases the effectiveness of some drugs.
Because dietary supplements are not drugs, interactions with drugs are not a
concern. (T/F) - Answer-False - Dietary supplement-drug interactions are changes in
a drug's effects caused by a dietary supplement taken during the same time period.
They are regulated as foods, but may interact with prescription or OTC drugs.
Ehrlich stated that an ideal drug (magic bullet) does not exist, would be aimed
precisely at a disease site, and would not harm healthy tissues. (T/F) - Answer-True
What is the difference between resistance and tolerance? - Answer-Tolerance refers
to a person's diminished response to a drug after repeated use, while resistance
applies to microorganism's or cancer cell's abilities to withstand drug effects.
Between 3% and 7% of hospital admissions in the U.S. are estimated to be for
treatment of adverse drug reactions. (T/F) - Answer-True
Which of the following would classify as Payers - Employers, patients, pharmacists,
or physicians? - Answer-Employers. - Some third party payers include the insurance
company, the employer, managed care organization, or the US government
(Medicaid and Medicare)
How would you define ethical pharmaceutical companies? - Answer-Ones that
research and develop novel drugs. - Research-based companies are the leading-
edge innovators. They develop branded drugs that are sufficiently novel to be
protected by patent from imitators. These firms are also known as ethical
pharmaceutical companies.
One of the most disappointing results of the pharmaceutical Industry's continued
investment in R&D is the few new drugs being approved and in development. (T/F) -
Answer-False - One of the most significant results of the pharmaceutical Industry's
continued investment in R&D is the large number of new drugs approved and in
development.
Thanks to modern medicines, how long are people newly diagnosed with HIV
expected to live? - Answer-Another 50 years.
How much has the average American lifespan increased since 1890? - Answer-
Almost 30 years. Since 1950 it has increased 10 years, from 68.2 to 78.7. Since
2009, it has risen 1.9 years for males and 1.6 years for females
What is a treatment group? - Answer-A group of patients assigned to receive a
specified treatment.
What is the main difference between a blinded and a double-blinded study? -
Answer-In a double blind study, neither the study staff nor the study participants
know which subjects are in the experimental group and which are in the control
group.
, What does asymptomatic mean? - Answer-Not exhibiting signs or symptoms.
What term denotes the study of bodily functions (as opposed to structures)? -
Answer-Physiology.
In its broadest definition, a drug is any substance that produces a physical or
psychological change in the body. (T/F) - Answer-True
How does the Federal Food, Drug and Cosmetic Act (FFDCA) define a drug? -
Answer-Any substance intended for use in the diagnosis, cure, mitigation, treatment,
or prevention of disease, or a substance other than food intended to affect the
structure or function of the body.
Most of the body's required vitamins must be taken from outside the body. (T/F) -
Answer-True
ADME testing measures the rate at which the body absorbs the drug, distributes it to
the organs necessary to produce the desired effect, metabolizes it into waste
material, and then excretes it from the body. (T/F) - Answer-True
There is no universal scale for quantifying the severity of an adverse drug reaction.
(T/F) - Answer-True - There is no universal scale for describing or measuring the
severity of an adverse drug reaction. Assessment is largely subjective. Reactions
can be described as mild, moderate, or severe.
Why is noncompliance a serious public health concern? - Answer-It increases the
cost of medical care.
Name 3 items available for which patent protection is available under U.S.
regulations. - Answer-The drug itself, the method of delivering and releasing the drug
into the bloodstream, and the way the drug is made.
Drugs' trade names are often unrelated to their intended use. (T/F) - Answer-False -
Trade names often suggest a characteristic of the drug
Like foods and household products, generic drugs are usually lower quality than the
brand name drugs for which they are marketed as equivalents. (T/F) - Answer-False
- Most generic drugs, although usually less expensive, are generally as effective and
of the same quality as the brand name drug
Legally, bioequivalence of different versions of a drug can vary by up to _____
percent. - Answer-20 - However, actual differences are typically only about 3.5% on
average and rarely exceed 10%
Biologics do not cause immune responses. (T/F) - Answer-False - Most, but not all
biologics (such as vaccines) work by triggering an immune response (One major
exception is blood and blood products).
