NURS 301 Exam 1: Arthritis Exam Questions
with Answers Verified by Experts
Uric Acid End product of protein metabolism and is normally excreted via urine
Non-specific marker - but normally associated with Gout
Anti-Citullinated Protein Antibody (ACPA) or Anti-CCP Specific diagnostic test for RA
May allow for earlier/more accurate diagnosis of Rheumatoid Arthritis
Antinuclear Antibody (ANA) Assess for antibodies capable of destroying the nucleus of
body tissues
Positive in 98% of SLE patients
ANA may also be positive with this disease: Rheumatoid Arthritis and a small percentage
in the normal population
,Anti-DNA Antibody Detects antibodies that react to DNA
*Most specific test of SLE
Complement Levels Complement is a normal body protein and is essential for both
immune and inflammatory reactions
Depletions may be found in RA or SLE
For example: people with active lupus erythematosus may have lower-than-normal levels of the
complement proteins C3 and C4
Osteoarthritis (OA) Involves the formation of new joint tissue (formation of osteophytes)
in response to cartilage destruction
Manifestations are local not systemic
,*Low-level of inflammation in the joint area
OA Clinical Manifestations *No systemic S/S
Joint pain - worsens with use and is relieved by rest
Change in temperature or barometric pressure can trigger pain
Pain - worsens with activity
Stiffness - worsens with inactivity
Crepitus - grating, crackling or popping sounds and sensations experienced under the skin and
joints
Asymmetrical pain
What is the typical reason why patients seek medical attention with OA? Joint pain
, Deformities Associated w/ OA Heberden's Nodes
Bouchard's Nodes
Bowlegged appearance
There are no specific biomarkers for OA: True
In OA the ESR value is normal unless: Synovitis is present
In OA the synovial fluid will appear: Clear, yellow with no signs of inflammation
This diagnostic tool is helpful in the staging/progression process of OA: X-ray
X-Ray Characteristics w/ OA Joint narrowing
with Answers Verified by Experts
Uric Acid End product of protein metabolism and is normally excreted via urine
Non-specific marker - but normally associated with Gout
Anti-Citullinated Protein Antibody (ACPA) or Anti-CCP Specific diagnostic test for RA
May allow for earlier/more accurate diagnosis of Rheumatoid Arthritis
Antinuclear Antibody (ANA) Assess for antibodies capable of destroying the nucleus of
body tissues
Positive in 98% of SLE patients
ANA may also be positive with this disease: Rheumatoid Arthritis and a small percentage
in the normal population
,Anti-DNA Antibody Detects antibodies that react to DNA
*Most specific test of SLE
Complement Levels Complement is a normal body protein and is essential for both
immune and inflammatory reactions
Depletions may be found in RA or SLE
For example: people with active lupus erythematosus may have lower-than-normal levels of the
complement proteins C3 and C4
Osteoarthritis (OA) Involves the formation of new joint tissue (formation of osteophytes)
in response to cartilage destruction
Manifestations are local not systemic
,*Low-level of inflammation in the joint area
OA Clinical Manifestations *No systemic S/S
Joint pain - worsens with use and is relieved by rest
Change in temperature or barometric pressure can trigger pain
Pain - worsens with activity
Stiffness - worsens with inactivity
Crepitus - grating, crackling or popping sounds and sensations experienced under the skin and
joints
Asymmetrical pain
What is the typical reason why patients seek medical attention with OA? Joint pain
, Deformities Associated w/ OA Heberden's Nodes
Bouchard's Nodes
Bowlegged appearance
There are no specific biomarkers for OA: True
In OA the ESR value is normal unless: Synovitis is present
In OA the synovial fluid will appear: Clear, yellow with no signs of inflammation
This diagnostic tool is helpful in the staging/progression process of OA: X-ray
X-Ray Characteristics w/ OA Joint narrowing
