NURS 300 Exam 2: Metabolic Syndrome and
PAD Questions and Answers 100% Solved
Adiponectin has an inverse relationship with the: Fat content or adiposity of the body
Increased adiposity - leads to decreased adiponectin (increases risk of insulin resistance)
Decreased adiposity - leads to increased adiponectin production
Leptin Increased adiposity - leads to increased leptin secretion
Leptin initiates satiety
*Overtime there becomes a resistance to Leptin and satiety decreases with obesity
Leptin also works with adiponectin to: Enhance insulin sensitivity
,Reduce TGs
Inhibit fat accumulation
Resistin Causes insulin resistance - negative effects
Enhances TG levels, decreases HDL levels and causes endothelial dysfunction
Angiotensinogen (AGT) Increases production with increased adipose tissue
Leads to increased BP, vascular resistance, Na and water retention
*Negative effects
Plasminogen Activator Inhibitor (PAI) Blocks the action of tissue plasminogen (tPA)
Plasminogen dissolves clots
, Increased obesity - increases PAI and block fibrinolysis
*Obesity increases susceptibility to clot formation
The greater the number of fat cells the greater the risk of cardiovascular disease because of:
Adipokines
Angiotensinogen (AGT)
PAI
Excessive Adipocytes Causes: Increased FFA
Increase tumor necrosis factor (TNF)
Increased angiotensinogen (AGT)
Increased PAI
Increased resistin
Increased leptin resistance
PAD Questions and Answers 100% Solved
Adiponectin has an inverse relationship with the: Fat content or adiposity of the body
Increased adiposity - leads to decreased adiponectin (increases risk of insulin resistance)
Decreased adiposity - leads to increased adiponectin production
Leptin Increased adiposity - leads to increased leptin secretion
Leptin initiates satiety
*Overtime there becomes a resistance to Leptin and satiety decreases with obesity
Leptin also works with adiponectin to: Enhance insulin sensitivity
,Reduce TGs
Inhibit fat accumulation
Resistin Causes insulin resistance - negative effects
Enhances TG levels, decreases HDL levels and causes endothelial dysfunction
Angiotensinogen (AGT) Increases production with increased adipose tissue
Leads to increased BP, vascular resistance, Na and water retention
*Negative effects
Plasminogen Activator Inhibitor (PAI) Blocks the action of tissue plasminogen (tPA)
Plasminogen dissolves clots
, Increased obesity - increases PAI and block fibrinolysis
*Obesity increases susceptibility to clot formation
The greater the number of fat cells the greater the risk of cardiovascular disease because of:
Adipokines
Angiotensinogen (AGT)
PAI
Excessive Adipocytes Causes: Increased FFA
Increase tumor necrosis factor (TNF)
Increased angiotensinogen (AGT)
Increased PAI
Increased resistin
Increased leptin resistance
