Clayton's Basic Pharmacology for Nurses:
Chapter 2
drugs do not create new responses but rather - correct answer alter existing physiologic activity
in several different ways
specific sites which the drug usually forms chemical bonds with - correct answer receptors
a drug only forms a bond with a receptor if: - correct answer - the drug and the receptor have
similar shapes
- the drug has a chemical affinity for the receptor
the study of the interactions between drugs and their receptors and the series of events that
result in a pharmacologic response - correct answer pharmacodynamics
T/F: the better the fit between the receptor and the drug molecule the better the response of
the drug - correct answer T
drugs that interact with a receptor to stimulate a response are known as - correct answer
agonists
drugs that attach to a receptor but do not stimulate a response - correct answer antagonists
drugs that interact with a receptor to stimulate a response but inhibit other responses - correct
answer partial agonists
3 routes of drug administration: - correct answer - enteral
- parenteral
- percutaneous
, Clayton's Basic Pharmacology for Nurses:
Chapter 2
when using the _______________ route, the drug is administered directly into the GI tract by
oral, rectal, or nasogastric route - correct answer enteral
when using the _________________ route, the drug bypasses the GI tract with the use of
subcutaneous, intramuscular, or intravenous injection - correct answer parenteral
when using the ___________________ route, the drug is absorbed through the skin and
mucous membranes - correct answer percutaneous
after administration, all drugs go through 5 stages: - correct answer - liberation
- absorption
- distribution
- metabolism
- excretion
the study of what the body does to the drug - correct answer pharmacokinetics
release of a drug from the dosage form to be dissolved in body fluids for absorption - correct
answer liberation
liberation of a drug within the body can be manipulated by: - correct answer - pharmaceutical
dosage form used (e.g. solution, suspension, capsule, tablet)
- administering the drug with or without food and water in the patient's stomach
the process whereby a drug is transferred from its site of entry into the body to the circulating
fluids of the body for distribution around the body - correct answer absorption
Chapter 2
drugs do not create new responses but rather - correct answer alter existing physiologic activity
in several different ways
specific sites which the drug usually forms chemical bonds with - correct answer receptors
a drug only forms a bond with a receptor if: - correct answer - the drug and the receptor have
similar shapes
- the drug has a chemical affinity for the receptor
the study of the interactions between drugs and their receptors and the series of events that
result in a pharmacologic response - correct answer pharmacodynamics
T/F: the better the fit between the receptor and the drug molecule the better the response of
the drug - correct answer T
drugs that interact with a receptor to stimulate a response are known as - correct answer
agonists
drugs that attach to a receptor but do not stimulate a response - correct answer antagonists
drugs that interact with a receptor to stimulate a response but inhibit other responses - correct
answer partial agonists
3 routes of drug administration: - correct answer - enteral
- parenteral
- percutaneous
, Clayton's Basic Pharmacology for Nurses:
Chapter 2
when using the _______________ route, the drug is administered directly into the GI tract by
oral, rectal, or nasogastric route - correct answer enteral
when using the _________________ route, the drug bypasses the GI tract with the use of
subcutaneous, intramuscular, or intravenous injection - correct answer parenteral
when using the ___________________ route, the drug is absorbed through the skin and
mucous membranes - correct answer percutaneous
after administration, all drugs go through 5 stages: - correct answer - liberation
- absorption
- distribution
- metabolism
- excretion
the study of what the body does to the drug - correct answer pharmacokinetics
release of a drug from the dosage form to be dissolved in body fluids for absorption - correct
answer liberation
liberation of a drug within the body can be manipulated by: - correct answer - pharmaceutical
dosage form used (e.g. solution, suspension, capsule, tablet)
- administering the drug with or without food and water in the patient's stomach
the process whereby a drug is transferred from its site of entry into the body to the circulating
fluids of the body for distribution around the body - correct answer absorption
