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NR 568 Week 8 Final Exam Study Guide (Weeks 5-8)

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NR 568 Week 8 Final Exam Study Guide (Weeks 5-8)

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NR568 Final Exam Study
Guide



Week 5


- Prevention of osteoporosis with hormone replacement therapy

HT reduces postmenopausal bone loss and thereby decreases the risk for
osteoporosis and related fractures.

The first line of prevention and treatment of osteoporosis is hormone replacement
therapy (HRT). All of the approved drugs for the prevention and treatment of
osteoporosis act as inhibitors of bone resorption; these drugs include HRT, selective
estrogen receptor modulators, calcitonin, and bisphosphonates

- When and when not to use progestin for hormone replacement therapy and why

You should not use HRT (Estrogen with or without Progestin) for the prevention or
treatment of coronary heart disease or stroke. HRT (Estrogen with or without
Progestin) is effective for the control of hot flashes, night sweats and vaginal
dryness.
Local vs. systemic estrogen options and why one would be chosen over the other
Prostaglandins
I. Prostaglandins, a group of lipids, originate from the fatty acids and act as a
middleman. The hormone rushes to the work whenever there is an incident
of tissue damage. Hence, the primary attribution of these molecules is to
clot blood and form new cells on the wounded site. They do the task by
inhibiting the aggregation of the platelet.
II. Aside from that, prostaglandins control the inflammation due to injury,
blood pressure, and blood flow. Furthermore, the hormone also contributes
to uterine contraction during pregnancy labor.
Leukotrienes
I. Leukotrienes, the inflammatory chemical group, are responsible for your
suffering during an allergy attack. These hormones signal the airway
muscles to tighten and release excess mucus as soon as you make any
contact with an allergen. The leukotrienes also cause lung swelling in asthma
and play an inflammatory role in tissue damage or injury.
Histamine
I. Histamine fights on your behalf against any potential allergy or alien
that invades your immunity system. Your while blood cells secrete these
compounds whenever under attack. Such inflammatory responses
might trigger an allergic reaction in the body, such as itching or
sneezing.
II. Histamine has some other roles to perform too. The local hormone
1

, NR568 Final Exam Study
contributes in Guide
III. Smooth muscle contraction, Blood pressure regulation, Capillary
permeability enhancement by blood vessel dilation, Gastric juice
secretion, Serotonin




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