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Size and number of nucleoli in the cell depend on the ______________ of the cell. Correct
Answ_metabolic activity
Nuclear Pore Complex contains approx 40___________ Correct Answ_Nucleoporins
(NUPS)
Y complexes are made of _____________ nucleoporins and connect to the _____________.
Correct Answ_structural; cytoplasmic filaments
The hydrophobic mesh that limits the diffusion of molecules greater than 40kDa Correct
Answ_FG domains (nucleoporins)
Membrane NUPS are connected to the _____________. Correct Answ_nuclear basket
Nuclear protein that is synthesized in the cytoplasm, associates with cytoplasmic filaments, and
is translocated into the nucleus Correct Answ_Nucleoplasmin
, Three things cytosol-nuclear transport requires Correct Answ_- energy
- specific protein receptors
- unique targeting signals
short stretch of positively charged amino acids (KKQRKK) Correct Answ_Classic Nuclear
Location Signal
two short stretches of basic amino acids and a 7-10 spacer sequence; found in nucleoplasmin
(KR________KKKK) Correct Answ_Barpartite Nuclear Location Signal
____________ are known as importins and exportins Correct Answ_Karyopherins (types of
transport receptors)
Mutation in the SRY gene or TDF causing mutation in NLS and cannot enter the nucleus to
execute it's function Correct Answ_Swyer Syndrome
SRY acts on ____________ to suppress it's activity of transcribing female phenotypes
Correct Answ_Beta-cretinine