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Pharmcology exam 1

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Which nursing intervention concerning drug therapy should the nurse implement? (Select all the apply) A) Assessing for side effects of drugs, especially those that are non selective B)Checking the drug reference books for dosage ranges, side effects, protein-binding, percentage, and half-life C) teaching the client to wait a week after occurrence of signs and symptoms to see if they disappear D) checking the client's serum therapeutic range of drugs that are more toxic or have a narrow therapeutic range. - correct answers-Assessing for side effects of drugs, especially those that are non selective Checking the drug reference books for dosage ranges, side effects, protein-binding, percentage, and half-life Agonists and Antagonists - correct answers-Agonistic drugs are those that work to mimic the effect of a neurotransmitter in the brain. Antagonistic drugs work by blocking neurotransmitters in the brain. in the Why we use Z track administration? - correct answers-The Z-track method of intra-muscular (I.M.) injection is used primarily when giving dark-colored medication solutions, such as iron solutions, that can stain the subcutaneous tissue or skin. It is also the method of choice when giving I.M. medications that are very irritating to the tissue, such as haloperidol or vistaril. Precautions taken when giving Z-track injections are all aimed at preventing the medication from leaking into the subcutaneous tissue or skin. Onset - correct answers-Time it takes a drug to reach minimum effective concentration Peak Action - correct answers-Occurs when a drug has reached its highest plasma concentration Duration of Action - correct answers-Length of time a drug has a pharmacologic effect Therapeutic Index - correct answers-The margin of safety of a drug Understand why one brand may be better than another brand even with same generic active ingredient? - correct answers-The base? Plasma drug levels - correct answers-Minimum effective concentration, Toxic concentration Minimum effective concentration - correct answers-Plasma drug level below which therapeutic effects will not occur Toxic Concentration - correct answers-When plasma drug levels climb too high Drug Half-life - correct answers-The time required for the amount of drug in the body to decrease by 50% Dosing of medication - correct answers-Drug levels rise as the medicine undergoes absorption, then the drug levels decline as metabolism and excretion eliminate the drug from the body.

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Institution
Pharmcology
Course
Pharmcology

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pharmcology exam 1

Pharmaceutics - correct answers-Dissolution of drug
Pharmokenetics - correct answers-Effect of drug action because of hereditary influence
Pharmokenetics - correct answers-Determining how much of an administered dose gets
to its site of action: Absorption, distribution, Metabolism, excretion
Clinical Pharmacology - correct answers-Studies of drugs in humans
Ideal Drug Properties - correct answers-Effectiveness, Safety, Selectivity, Reversible
Action, Predictability, Ease of Administration, Freedom from drug interactions, Low
Cost, Chemical Stability, Possession of a simple generic name
Pharmodynamics - correct answers-Impact of drugs on body
ADPIE - correct answers-Pre-administration ASSESSMENT
*Collecting baseline data for Therapeutic and adverse effects
*Identifying high-risk patients
*Capacity for self-care
Dosage and Administration
*Certain Drugs have more than one indication
*Drugs may have more than one route and dosage can differ
*Certain IV agents can cause severe local injury if line is extravasated
Planning (intervention) minimizing adverse effects and interactions
*Defining Goals
*Setting Priorities
*Identifying Interventions
-Drug administration
-Enhancing therapeutic effects
-Minimizing adverse effects
-Patient Education
Implementation
*Enhancing drug therapy, biofeedback, emotional support
*Enhancing drug therapy through exercise, physical therapy, and rest
*Enhancing through weight reduction, smoking cessation, sodium restriction
Evaluation- Making PRN decisions/managing toxicity
*Know rationale for treatment
Objective of drug therapy - correct answers-Provide maximum benefit with minimum
harm
Rights of medication administration - correct answers-Right Drug
Right Patient
Right Dose
Right Route
Right Time
Right Documentation
Adherence (Concordance) - correct answers-Extent to which a patient's behavior
coincides with medical advice

, Which drug form is most rapidly absorbed from the GI tract?
A) tablet
B) enteric-coated tablet
C) suspension
D) poutice - correct answers-C) Suspension
Usually food has what effect on drug dissolution and absorption?
A) enhances
B) Interferes with
C) does not affect
D) catalytic - correct answers-B) interferes with
Which statement places the four processes of pharmacokinetics in the correct
sequence?
A) absorption, metabolism, distribution, excretion
B) distribution, absorption, metabolism, excretion
C) distribution, metabolism, absorption, excretion
D) absorption, distribution, metabolism, excretion - correct answers-D) absorption,
distribution, metabolism, excretion
Which type of drug passes rapidly through the GI membrane?
A) lipid- soluble and ionized
B) lipid- soluble and non-ionized
C) water-soluble and ionized
D) water-soluble and non-ionized - correct answers-B) lipid-soluble and non-ionized
Which factors most commonly affect a drug's interaction?
A) Poor circulation, pain, stress, hunger, fasting
B) stress, hunger, weather, ph of drug
C)poor circulation, hunger, stress, BMI
D)BMI, ph of drug, stress, poor circulation - correct answers-A) Poor circulation, pain,
stress, hunger, fasting
A client is taking a drug that is highly protein-bound. Several days later, the client takes
a second drug that is 90% protein-bound. What happens to the first drug?
A) The first drug remains highly protein bound
B) The first drug becomes increasingly inactive
C) More of the first drug is released from the protein and becomes more
pharmacologically active
D) The first drug is excreted in the urine - correct answers-C) More of the first drug is
released from the protein and becomes more pharmacologically active
Which body organ is the major site of drug metabolism?
A)Kidney
B) liver
C) Lung
D) Skin - correct answers-B Liver
What route of drug absorption has the greatest bioavailability
A) oral
B) intramuscular
C)subcutaneous
D)intravenous - correct answers-D)intravenous

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Institution
Pharmcology
Course
Pharmcology

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March 26, 2025
Number of pages
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Written in
2024/2025
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