PMHNP certification
5HT2C - ANS--activation of this recent inhibits dopamine and norepinephrine
-antagonists: quetiapine, olanzapine, fluoxetine, mirtazapine.
\Abnormal Potassium levels - ANS-Increased: amiloride, spironolactone, lithium, propranolol.
Decreased
\Abnormal sodium levels - ANS--increased: dehydration, methyldopa,
-decreased: SIADH, heart failure, nephrotic syndrome, hepatic disease.
\absolute neutrophil count calculations - ANS-total WBC x percentage of neutrophil in
differential=ANC
\Advance directive - ANS--a legal document that can be in the form of a living will, power of
attorney, healthcare proxy
\age-associated changes in pharmacodynamics and pharmacokinetics - ANS--distribution:
more adipose tissue; less water
-SSRI can induce hyponatremia
-more sensitive to the effects of benzodiazepines
-decreased dopamine and acetylcholine synthesis in elderly and thus they are more
sensitive to D2 antagonists and antimuscarinics.
\Alcohol withdrawal treatment - ANS-100mg Thiamine PO for 5 days
-multivitamin that includes folate
-1st day-- q6hr librium 50 mg
-for the next two days-- q6hr librium 25mg.
OR
-1st day--Q6hr lorazepam 2-4mg
-for the next two days-Q6hr lorazepam 1-2 mg
\alpha 1 antagonists - ANS--vasodilator and used for hypertension
-raynauds
-PTSD and GAD
-benign prostatic hyperplasia (tamsulosin)
-agonism: vasoconstrictor
-trazadone and many antipsychotics
\alzheimers - ANS--altered processing of amyloid processing protein, rendering it toxic.
Amyloid plaques prompt a cascade of intracellular events resulting in microtubules being
converted into neurofibrillary tangles
-MRI usually not utilized as a diagnostic tool but should used to rule out diseases like chronic
subdural hematoma
\anion gap - ANS-the difference between cations and anion.
-is calculated to identify reason for metabolic acidosis
-cations: sodium and potassium
-anions: chloride and bicarbonate
-normal anion gap: 8-16mEq/L
-high anion gap: high levels of lactate (an anion) prompt an increase in excretion of
bicarbonate to maintain electroneutrality
-normal anion gap: drop in bicarbonate but an increase in chloride
\antidepressants with minimal effect on cyp 2D6 - ANS--effexor and escitalopram
, \Antipsychotics that cause the most hypotension - ANS-olanzapine, risperidone, quetiapine
\aphasia, agnosia - ANS-aphasia: impairment in language function
agnosia (ag-nosh-a): inability to process sensory information. Loss in the ability to recognize
familiar objects.
\aripiprazole long acting - ANS--maximum concentration is achieved 5 to 7 days after
injection
-starting dose is 400mg
-continue oral abilify 10 to 20mg for 14 days
-administered in the gluteal muscle
\Assessment tools to screen for cognitive impairment - ANS--folstein mini-mental: perfect
score is 30. <24 impairment. If only 9th grade education <17
\autism - ANS-appears before the age of 3. Difficulty with communication
-pervasive failure to form social relationships
-problems with communication
-ritualistic behaviors
-stereotyped behavior
-circumscribed range of interests
\autism pharmacology - ANS--greater sensitivity or idiosyncratic effects from medication
-do not use anticonvusants
\b12 deficiency - ANS--surgical removal of the stomach, pancreatic inflammation,
-MCV>100. symptoms of megaloblastic anemia are due to impaired DNA synthesis and are
most apparent in rapidly dividing cells such as blood cells and gastrointestinal cell
-absorbed in the distal ileum
-h2 antagonist may inhibit the release of intrinsic factor
-B12 and folate deficiency are not easily differentiated; accordingly, patients should be
screened for both immediately upon admission.
\Beck's Cognitive Theory - ANS--negative automatic thoughts are the cause of depression
-Beck's Cognitive Triad: negative thoughts are revolve around the self, the future, and the
world
\Bioequivalence - ANS-When the active ingredient of two drug products have the same rate
and extent of absorption.
\biomedical psychiatry - ANS-mental illness is conceptualized as a disorder of the brain
circuit caused by a complex interplay of genetic and environmental factor
\Bowen's family system - ANS--differentiation-->ego strength. Differentiation is how well can
the individual think through a situation without be drawn into internal or external pressures.
-emotional fusion: family members sharing the same response
-triangles: When the relationship between two family members become stressed, a third
member is brought in to reduce anxiety
\bulimia Laboratory finding - ANS--induced vomiting may cause metabolic alkalosis: elevated
bicarbonate, hypochloremia, hypokalemia
-Increased BUN indicates dehydration
\Buspirone - ANS-\
5HT1a partial agonist.
initial 15 mg BID
-no sexual dysfunction
\CAGE - ANS-items responses are scored either 1 or 0. A score 2 or higher is considered
clinically significant
5HT2C - ANS--activation of this recent inhibits dopamine and norepinephrine
-antagonists: quetiapine, olanzapine, fluoxetine, mirtazapine.
\Abnormal Potassium levels - ANS-Increased: amiloride, spironolactone, lithium, propranolol.
Decreased
\Abnormal sodium levels - ANS--increased: dehydration, methyldopa,
-decreased: SIADH, heart failure, nephrotic syndrome, hepatic disease.
\absolute neutrophil count calculations - ANS-total WBC x percentage of neutrophil in
differential=ANC
\Advance directive - ANS--a legal document that can be in the form of a living will, power of
attorney, healthcare proxy
\age-associated changes in pharmacodynamics and pharmacokinetics - ANS--distribution:
more adipose tissue; less water
-SSRI can induce hyponatremia
-more sensitive to the effects of benzodiazepines
-decreased dopamine and acetylcholine synthesis in elderly and thus they are more
sensitive to D2 antagonists and antimuscarinics.
\Alcohol withdrawal treatment - ANS-100mg Thiamine PO for 5 days
-multivitamin that includes folate
-1st day-- q6hr librium 50 mg
-for the next two days-- q6hr librium 25mg.
OR
-1st day--Q6hr lorazepam 2-4mg
-for the next two days-Q6hr lorazepam 1-2 mg
\alpha 1 antagonists - ANS--vasodilator and used for hypertension
-raynauds
-PTSD and GAD
-benign prostatic hyperplasia (tamsulosin)
-agonism: vasoconstrictor
-trazadone and many antipsychotics
\alzheimers - ANS--altered processing of amyloid processing protein, rendering it toxic.
Amyloid plaques prompt a cascade of intracellular events resulting in microtubules being
converted into neurofibrillary tangles
-MRI usually not utilized as a diagnostic tool but should used to rule out diseases like chronic
subdural hematoma
\anion gap - ANS-the difference between cations and anion.
-is calculated to identify reason for metabolic acidosis
-cations: sodium and potassium
-anions: chloride and bicarbonate
-normal anion gap: 8-16mEq/L
-high anion gap: high levels of lactate (an anion) prompt an increase in excretion of
bicarbonate to maintain electroneutrality
-normal anion gap: drop in bicarbonate but an increase in chloride
\antidepressants with minimal effect on cyp 2D6 - ANS--effexor and escitalopram
, \Antipsychotics that cause the most hypotension - ANS-olanzapine, risperidone, quetiapine
\aphasia, agnosia - ANS-aphasia: impairment in language function
agnosia (ag-nosh-a): inability to process sensory information. Loss in the ability to recognize
familiar objects.
\aripiprazole long acting - ANS--maximum concentration is achieved 5 to 7 days after
injection
-starting dose is 400mg
-continue oral abilify 10 to 20mg for 14 days
-administered in the gluteal muscle
\Assessment tools to screen for cognitive impairment - ANS--folstein mini-mental: perfect
score is 30. <24 impairment. If only 9th grade education <17
\autism - ANS-appears before the age of 3. Difficulty with communication
-pervasive failure to form social relationships
-problems with communication
-ritualistic behaviors
-stereotyped behavior
-circumscribed range of interests
\autism pharmacology - ANS--greater sensitivity or idiosyncratic effects from medication
-do not use anticonvusants
\b12 deficiency - ANS--surgical removal of the stomach, pancreatic inflammation,
-MCV>100. symptoms of megaloblastic anemia are due to impaired DNA synthesis and are
most apparent in rapidly dividing cells such as blood cells and gastrointestinal cell
-absorbed in the distal ileum
-h2 antagonist may inhibit the release of intrinsic factor
-B12 and folate deficiency are not easily differentiated; accordingly, patients should be
screened for both immediately upon admission.
\Beck's Cognitive Theory - ANS--negative automatic thoughts are the cause of depression
-Beck's Cognitive Triad: negative thoughts are revolve around the self, the future, and the
world
\Bioequivalence - ANS-When the active ingredient of two drug products have the same rate
and extent of absorption.
\biomedical psychiatry - ANS-mental illness is conceptualized as a disorder of the brain
circuit caused by a complex interplay of genetic and environmental factor
\Bowen's family system - ANS--differentiation-->ego strength. Differentiation is how well can
the individual think through a situation without be drawn into internal or external pressures.
-emotional fusion: family members sharing the same response
-triangles: When the relationship between two family members become stressed, a third
member is brought in to reduce anxiety
\bulimia Laboratory finding - ANS--induced vomiting may cause metabolic alkalosis: elevated
bicarbonate, hypochloremia, hypokalemia
-Increased BUN indicates dehydration
\Buspirone - ANS-\
5HT1a partial agonist.
initial 15 mg BID
-no sexual dysfunction
\CAGE - ANS-items responses are scored either 1 or 0. A score 2 or higher is considered
clinically significant
