Review Study Guide Newest Actual
Questions & Answers (A+ Guide
Solution)
naltrexone class - Correct answerOpioid receptor antagonist
Naltrexone can be used for - Correct answerboth ETOH and opioid use disorders
What does naltrexone do - Correct answerReduces desire/cravings, First line
treatment, Will precipitate withdrawal in patients with physical opioid dependence
First line treatment in maintaining abstinence after detox - Correct
answeracamprosate
acamprosate can be used - Correct answerin liver disease- not metabolized by the
liver (not impacted by ETOH use). Can be administered to patients with hepatitis, liver
disease, and those who continue drinking alcohol
acamprosate Contraindicated in - Correct answersevere renal disease
acamprosate helps with - Correct answerDecreasing cravings
ETOH 2nd line treatment - Correct answerdisulfiram (Antabuse)
disulfiram (Antabuse) causes - Correct answeraversion reaction to ETOH (flushing,
headaches, n/v, palpitation, SOB, vertigo, hypotension)
disulfiram (Antabuse) Do not - Correct answeradminister until the person has been
alcohol free at least 12 hours
disulfiram (Antabuse) MOA - Correct answerBlocks enzyme (aldehyde
dehydrogenase) in the liver
ETOH withdrawal- Benzos - Correct answerTo keep patient calm and lightly
sedated
Benzos MOA - Correct answerEnhance the effects of GABA
, Meds used in mild alcohol withdrawal - Correct answerTegretol, Valproic or
Gabapentin
ETHO meds for nutritional deficiencies - Correct answerThiamine, folic acid, and
multivitamin - 'Banana bag'
Wernicke's encephalopathy treatment - Correct answerParenteral Thiamine and
Folate
Wernicke's encephalopathy cause - Correct answerB1 deficiency
Cocaine mechanism - Correct answerreuptake of dopamine, epinephrine, and NE =
Stimulant effect
Cocaine effects on the body - Correct answerhas vasoconstrictive effects = can
cause MI, stroke
Cocaine treatment options - Correct answerNO FDA approved med; Off-label =
naltrexone, modafinil, Topamax
Antabuse in cocaine use disorder - Correct answerincrease synaptic dopamine in
the brain reward circuit and act as an agonist treatment in the setting of cocaine use
disorder
Medications for cocaine-induced chest pain - Correct answernitroglycerin & aspirin =
No metoprolol
Amphetamine treatment - Correct answerRehydrate, correct electrolyte, and treat
hyperthermia
PCP symptoms of intoxication - Correct answerNystagmus
Sedatives intoxication treatment - Correct answerBenzos = Flumazenil in OD
(Benzo antagonist)
PCP treatment options - Correct answerSupportive care (rehydration, electrolyte
balance etc.); Benzos for agitation, anxiety, muscle spasms; Haldol for severe agitation
and psychosis
Nicotine treatment - Correct answervarenicline (Chantix)
Varenicline (Chantix) MOA - Correct answermimics action of nicotine; most effective
tobacco cessation; Reduces rewarding aspects; Prevents withdrawal symptoms