Bacteria and viruses are both capable of growing within a human host and causing
disease. Which one of the following statements most accurately describes the features
of bacteria and viruses?
A. Bacteria have mitochondria allowing them to generate energy, whereas viruses are
reliant on the host cell for energy.
B. Because viruses lack a nucleolus, they can replicate independently of their hosts,
whereas bacteria rely on host proteins to replicate their genomes.
C. Bacterial ribosomes are composed of the same RNA and proteins as viral ribosomes.
D. Viruses can only replicate within a cell, whereas bacteria can replicate independently
of host cells.
Bacteria, fungi (yeasts and molds), viruses, and protozoa are important causes of
human diseases. Which one of the following microbes contains either DNA or RNA but
not both?
A. bacteria
B. molds
C. viruses
D. protozoa
E. yeasts
Which one of the following contains DNA that is not surrounded by a nuclear
membrane?
A. bacteria
B. molds
C. protozoa
D. yeasts
Mycobacterium tuberculosis stains well with the acid-fast stain, but not with the Gram
stain. Which one of the following is the most likely reason for this observation?
A. It has a large number of pili that absorb the purple dye.
B. It has a large amount of lipid that prevents entry of the purple dye.
C. It has a very thin cell wall that does not retain the purple dye
D. It is too thin to be seen in the Gram stain.
E. It has histones that are highly negatively charged.
,Bacteria that cause nosocomial (hospital-acquired) infections often produce
extracellular substances that allow them to stick firmly to medical devices, such as
intravenous catheters. Which one of the following is the name of this extracellular
substance?
A. axial filament
B. endotoxin
C. flagella
D. glycocalyx
E. porin
Several bacteria that form spores are important human pathogens. Which one of the
following is the most accurate statement about bacterial spores?
A. They are killed by boiling for 15 minutes.
B. They are produced primarily by gram-negative cocci.
C. They are formed primarily when the bacterium is exposed to antibiotics.
D. They are produced by anaerobes only in the presence of oxygen.
E. They are metabolically inactive, yet can survive for years in that inactive state.
Match the following bacteria to the correct description.
Bacteria: Staphylococcus, Clostridium, Neisseria, Mycobacterium, Yersinia
Description: gram (-) cocci, acid fast, gram (+) spore forming anaerobic rod, gram (-)
zoonotic rod, gram (+) cocci
1. staphylococcus= gram (+) cocci
2. clostridium= gram (+) spore forming anaerobic rod
3. Neisseria= gram (-) cocci
4. Mycobacterium= acid fast
5. Yersinia= gram (-) zoonotic rod
Match the disease to the correct causative organism.
Disease: Syphilis, Lyme disease, Cholera, Gonorrhea, Tetanus
Causative Organism: Vibrio, Neisseria, Clostridium, Treponema, Borrelia
1. Syphilis= treponema
2. Lyme disease= Borrelia
3. Cholera= Vibrio
4. Gonorrhea= Neisseria
5. Tetanus= Clostridium
Genome DNA sequencing is the current gold standard to classify organisms.
True or False
True
, The proteins on the external surface of viruses serve several important functions.
Regarding these proteins, which one of the following statements is most accurate?
A. They are the antigens against which neutralizing antibodies are formed.
B. They are the polymerases that synthesize viral messenger RNA.
C. They are the proteases that degrade cellular proteins leading to cell death.
D. They are the proteins that regulate viral transcription.
E. Change in conformation of these proteins can result in prion-mediated diseases such
as Creutzfeldt-Jakob disease.
A defective virus cannot synthesize a protein required for replication and therefore can
only replicate within a cell infected by a helper virus. Which of the following is a
defective virus?
A. Hepatitis A virus
B. Hepatitis B virus
C. Hepatitis C virus
D. Hepatitis D virus
E. Hepatitis E virus
Viruses contain both DNA and RNA.
True or False
False
Regarding respiratory syncytial virus (RSV), which one of the following statements is
most accurate?
A. RSV is an important cause of bronchiolitis in infants.
B. RSV causes tumors in newborn animals but not in humans.
C. The RSV vaccine is recommended for all children prior to entering school.
D. Amantadine should be given to elderly nursing home residents to prevent outbreaks
of disease caused by RSV.
E. RSV forms intranuclear inclusion bodies within neutrophils that are important in
diagnosis by the clinical laboratory.
Regarding Coronavirus Disease-19 (COVID-19) caused by SARS-CoV-2, which one of
the following statements is most accurate?
A. Symptoms of COVID-19 are limited to the lower respiratory tract.
B. Asymptomatic infections rarely occur.
C. The laboratory diagnosis can be made by either detection of viral RNA or detection of
antibodies to the spike protein.
D. Oseltamivir, a neuraminidase inhibitor, is used to treat severe COVID-19 disease.
E. A vaccine that protects against COVID-19 contains the messenger RNA encoding
the SARS-CoV-2 spike protein.