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MODERNBLOODBA l l
NKING&TRANSFUS
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IONPRACTICES6TH
l l l
EDITIONDENISEM.
l l l
HARMENING
,TEST BANK FOR
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MODERN BLOOD BANKING
l l l
& TRANSFUSION PRACTICES
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6TH EDITION
l
DENISE M. HARMENING
l l
, Chapter 1 RBCs and Platelet Preservation: Historical Perspectives and Current Trends
l l l l l l l l l l
MultiplelChoice
Identifylthelchoicelthatlbestlcompleteslthelstatementlorlanswerslthelquestion.
l 1.l Whichlmetaboliclpathwaylislresponsiblelforlgeneratingl90%loflthelATPlforlthelRBC?
a. Pentoselphosphatelshunt c. Glycolysis
b. Luebering-Rapoportlshunt d.l Methemoglobinlreductase
l
2.l Alunitloflbloodlwaslreturnedltolthelbloodlbanklbeforelitlwaslspiked.lApparentlylthelpatient’slIVlfailed.lThelu
nitloflbloodlwasloutsidelthelbloodlbanklforl35lminutes.lWhichloflthelstatementslbelowlislmostlaccurate?
a. Thelunitloflbloodlshouldlbeldiscardedlimmediately.
b. Thelunitloflbloodlcanlbelreturnedltolinventory.
c. Thelunitloflbloodlmustlbeltransfusedlwithinl4lhourslorlbeldiscardedlatlthelendloflthatltime.
d. Thelunitloflbloodlmustlbeltransfusedlwithl24lhours.
l 3.l Whatlislthelaverageldiameterloflalplatelet?
a. 5ltol10lµm c. 1ltol2lµm
b. 2ltol4lµm d.lll 4ltol6lµm
l 4.lInlthelnormallhemoglobin-
oxygenldissociationlcurve,lwhatlpercentagelofloxygenlislreleasedltoltheltissueslwhenlPO2laveragesl40lmmlHg
?
a. 75% c. 100%
b.lll 25% d.l 50%
l 5.l Whatlfactorslarelknownltolinfluencelplateletlmetabolismlandlfunction?
a. Storageltemperature c. Plateletlcount
b. InitiallpH d.l Allloflthelabove
l
6.lWhichloflthelfollowinglredlbloodlcelllmorphologieslmaylbelpresentlonlthelperipherallbloodlsmearlaslalresultl
ofllossloflRBClmembrane?
a. Spherocytes c. Burrlcells
b. Targetlcells d.l Schistocytes
l 7.l Whatldoesltheltermlautologousltransfusionlreferlto?
a. Alparentldonatinglbloodlforlhislorlherlchild
b. Anlindividualldonatinglbloodlforlalfriend
c. Anlindividualldonatinglbloodlforlalrelative
d. Anlindividualldonatinglbloodlforlhislorlherlownltransfusion
l 8.l Whatlislthelprimarylfunctionloflhemoglobin?
a. Ironlmetabolism c. Oxygenltransport
b. Porphyrinlsynthesis d.l Signalltransduction
l 9.l Allloflthelfollowinglareasloflredlbloodlcelllbiologylarelcruciallforlnormallerythrocytelsurvivall except:
a. Cellularlmetabolism. c. SiteloflthelABOlantigenlattachment.
b. RBClmembrane. d.l Hemoglobinlstructure.
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, l ll 10.l WhatlislthelcorrectlbiochemicallcompositionloflthelRBClmembrane?
a. 52%lprotein,l40%llipid,l8%lcarbohydrate
b. 40%lprotein,l8%llipid,l52%lcarbohydrate
c. 8%lprotein,l52%llipid,l40%lcarbohydrate
d. 8%llipid,l40%lcarbohydrate,l52%lprotein
l lll 11.l Allloflthelfollowinglbiochemicallchangeslarelassociatedlwithllossloflredlbloodlcelllviabilityluponlstorage
except:
a. DecreasedlpH. c. IncreasedlATPllevel.
b. Lossloflredlbloodlcelllfunction. d.l Decreasedlglucoselconsumption.
l ll 12.l Whichlredlbloodlcelllpreservativelhaslalstorageltimelofl35ldays?
a. ACD c. AS-1
b. CPDA-1 d.lll CPD
l ll 13.l ThelRBClmembranelislrelativelylpermeableltolallloflthelfollowinglexcept:
a. Chloride. c. Bicarbonate.
b. Sodium. d.l Water.
l
ll 14.lWhatlpercentageloflplateletslislsequesteredlinlthelspleenlaslfunctionallreservelafterlbeinglreleasedlfromlt
helbonelmarrow?
a. 30% c. 10%
b.lll 50% d.lll 25%
l ll 15.l Whatlislthelmajorlbiochemicallconsiderationlinlplateletlstorage?
a. Glucoselmetabolism c. Productionloflcarbonldioxide
b. Oxygenlsupply d.l RegulationloflpH
l ll 16.lWhatlwouldlthelhemoglobin-
oxygenldissociationlcurveldepictlinlalpatientlexhibitinglclinicallsignsloflalkalosis?
a. Normal c. Shiftltolthelright
b. Shiftltolthelleft d.l Noneloflthelabove
l ll 17.l Namelthelmainllipidlcomponentsloflalredlbloodlcelllmembrane.
a. Phospholipid c. Glycolipid
b. Sphingomyelin d.l GlycophorinlA
l ll 18.l ThelABOlbloodlgroupslwereldiscoveredlinl1901lbylwhom?
a. CharleslDrew c. LoutitlandlMollison
b. KarllLandsteiner d.l EdwardlLindeman
l
19.lAlstandinglorderloflplateletslwaslshippedltolyourlfacilitylbylyourlsupplier.lItlwaslinadvertentlylleftlinlthelc
ll
ornerlofltheldepartmentluntilldiscoveredl36lhoursllater.lWhatlwouldlthelappropriatelactionlbelforlthelbloodlbanke
r?
a. Ifltheltemperaturelinlthelboxlwasl22l+/-
l2°ClandlthelplateletlswirllseemedlOK,litlwouldlbelOKltolacceptlthelunitlintolinventory.
b. Thelplateletslhavelfallenloutsidelthelsupplier’slqualitylassurance.lThelunitlshouldlbe
discardedlbecauselthelpHlhaslprobablyldroppedltoollowlandlplateletlactivationlhaslbeenlcompromised.
c. Ifltheltemperaturelwasl1°Cltol6°ClandlthelplateletlswirllseemedlOK,litlwouldlbelOKlto
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