WELLBUTRIN
GENERIC NAME: BUPROPION
Drug Class: Antidepressant
NAMES PURPOSE/THERAPEUTIC USES
Generic Name: Bupropion • Inhibitor of the neuronal uptake of norepinephrine and
dopamine
Brand Name(s): Wellbutrin XL, • Treat depression
Wellbutrin SR, Forfivo XL, • To aid in smoking cessation
• Can be used as an alternative treatment of ADHD
Aplenzin, Zyban
DIAGNOSES TREATED
Side Effects/Adverse Reactions
◦ MAJOR DEPRESSIVE
Headache More severe
DISORDER (MDD) Weight loss Skin rash
◦ SEASONAL AFFECTIVE Dry mouth Sweating
Insomnia Tinnitus
DISORDER (SAD)
Nausea Angle-closure glaucoma
Dizziness Generalized seizures
Constipation Psychosis, Mania
DOSAGING Tachycardia HTN
Sore throat
Tablet
Agitation, irritability
Wellbutrin SR: 100mg, 150mg, 200mg
Wellbutrin XL: 150mg, 300mg
Zyban: 150mg Nursing Considerations
Forfivo XL: 450mg
Assess mental status and change in behavior
Aplenzin: 174mg, 348mg, 522mg
Assess for increased signs of depression
Bupropion hydrochloride
Monitor weight and food intake
IR: 75mg, 100mg
Monitor for seizures
SR: 100mg, 150mg, 200mg
ER: 150mg, 300mg
Contraindications
Bupropion bromide ER: 174mg, 348mg,
522mg Seizure disorder
History of bulimia or anorexia nervosa
ADDITIONAL INFO Abrupt alcohol or sedative cessation
MAO inhibitors
Bupropion products are not interchangeable Hepatic Impairment
CNS tumor or CNS infection
GENERIC NAME: BUPROPION
Drug Class: Antidepressant
NAMES PURPOSE/THERAPEUTIC USES
Generic Name: Bupropion • Inhibitor of the neuronal uptake of norepinephrine and
dopamine
Brand Name(s): Wellbutrin XL, • Treat depression
Wellbutrin SR, Forfivo XL, • To aid in smoking cessation
• Can be used as an alternative treatment of ADHD
Aplenzin, Zyban
DIAGNOSES TREATED
Side Effects/Adverse Reactions
◦ MAJOR DEPRESSIVE
Headache More severe
DISORDER (MDD) Weight loss Skin rash
◦ SEASONAL AFFECTIVE Dry mouth Sweating
Insomnia Tinnitus
DISORDER (SAD)
Nausea Angle-closure glaucoma
Dizziness Generalized seizures
Constipation Psychosis, Mania
DOSAGING Tachycardia HTN
Sore throat
Tablet
Agitation, irritability
Wellbutrin SR: 100mg, 150mg, 200mg
Wellbutrin XL: 150mg, 300mg
Zyban: 150mg Nursing Considerations
Forfivo XL: 450mg
Assess mental status and change in behavior
Aplenzin: 174mg, 348mg, 522mg
Assess for increased signs of depression
Bupropion hydrochloride
Monitor weight and food intake
IR: 75mg, 100mg
Monitor for seizures
SR: 100mg, 150mg, 200mg
ER: 150mg, 300mg
Contraindications
Bupropion bromide ER: 174mg, 348mg,
522mg Seizure disorder
History of bulimia or anorexia nervosa
ADDITIONAL INFO Abrupt alcohol or sedative cessation
MAO inhibitors
Bupropion products are not interchangeable Hepatic Impairment
CNS tumor or CNS infection
