Pharmacology Exam 1 Rasmussen University questions
with verified answers
Absorption: Ans✓✓✓ -Drug enters body via circulation to reach target tissue
-Directly related to route of administration
-Impacted by:
-blood flow in GI tract
stress, hunger, fasting, food, pH, GI disease
-First-pass effect page 37: drugs must FIRST PASS from intestinal tract through
liver before can be utilized
-Bioavailability: percentage of drug that reaches systemic circulation
-Affected by:
drug form
route of administration
GI mucosa and motility, food and other drugs, liver dysfunction
Adverse effect/more severe Ans✓✓✓ -Unintended and occur at normal doses
-Always undesirable
-Mild-Serious, life threatening
-Nephrotoxic, Hepatotoxic
-Acute respiratory failure, anaphylaxis
-Always document and report
-Patient education essential (side vs. adverse vs. allergy)
, Agonist: Ans✓✓✓ drug activates or unlocks cell receptors, causing the
same/similar actions as the body's own chemicals.
Antagonist: Ans✓✓✓ Drug attaches at a drug receptor site but does not activate
or unlock the receptor. Drug prevents activation of the receptor.
Cytochrome P450 (CYP) isoenzymes Ans✓✓✓ liver enzyme pathway
-Liver primary organ
Desired characteristics of medication Ans✓✓✓ -Effectiveness: elicit the intended
response
Most important property a drug can have
Why?
Will we give a drug if it does not do what we want it to?
-Safety: a safe drug is "a drug that causes no harm"
All drugs can be harmful
Proper selection and dose related
-Selectivity: A drug that only produces the desired effect
Wholly selective drugs are unicorns!
All drugs have side effects
-Intensity - degree of response
Enteral (Route) Ans✓✓✓ -Liquid, tablets, caplets, suspensions
-Most convenient
with verified answers
Absorption: Ans✓✓✓ -Drug enters body via circulation to reach target tissue
-Directly related to route of administration
-Impacted by:
-blood flow in GI tract
stress, hunger, fasting, food, pH, GI disease
-First-pass effect page 37: drugs must FIRST PASS from intestinal tract through
liver before can be utilized
-Bioavailability: percentage of drug that reaches systemic circulation
-Affected by:
drug form
route of administration
GI mucosa and motility, food and other drugs, liver dysfunction
Adverse effect/more severe Ans✓✓✓ -Unintended and occur at normal doses
-Always undesirable
-Mild-Serious, life threatening
-Nephrotoxic, Hepatotoxic
-Acute respiratory failure, anaphylaxis
-Always document and report
-Patient education essential (side vs. adverse vs. allergy)
, Agonist: Ans✓✓✓ drug activates or unlocks cell receptors, causing the
same/similar actions as the body's own chemicals.
Antagonist: Ans✓✓✓ Drug attaches at a drug receptor site but does not activate
or unlock the receptor. Drug prevents activation of the receptor.
Cytochrome P450 (CYP) isoenzymes Ans✓✓✓ liver enzyme pathway
-Liver primary organ
Desired characteristics of medication Ans✓✓✓ -Effectiveness: elicit the intended
response
Most important property a drug can have
Why?
Will we give a drug if it does not do what we want it to?
-Safety: a safe drug is "a drug that causes no harm"
All drugs can be harmful
Proper selection and dose related
-Selectivity: A drug that only produces the desired effect
Wholly selective drugs are unicorns!
All drugs have side effects
-Intensity - degree of response
Enteral (Route) Ans✓✓✓ -Liquid, tablets, caplets, suspensions
-Most convenient
