D116 NURS 6800
Advanced Pharmacology
FA Review (Qns & Ans)
2025
1. Multiple Choice
Question : Which pharmacokinetic process refers to the
movement of a drug from the site of administration into the
bloodstream?
a) Absorption
b) Distribution
c) Metabolism
d) Excretion
©2025
, ANS : a) Absorption
Rationale : Absorption is the first pharmacokinetic process
through which a drug enters the bloodstream, allowing it to reach
systemic circulation.
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2. Fill-in-the-Blank
Question : The __________ effect refers to the metabolism of a
drug by the liver before it reaches systemic circulation.
ANS : First-pass
Rationale : The first-pass effect occurs when oral medications
are metabolized in the liver, reducing the amount available for
systemic circulation.
---
3. True/False
Question : A narrow therapeutic index indicates that a drug is
safer and requires less monitoring.
ANS : False
©2025
, Rationale : Drugs with a narrow therapeutic index have a small
margin between therapeutic and toxic doses, requiring careful
monitoring.
---
4. Multiple Response
Question : Which factors affect drug metabolism in the liver?
a) Age of the patient
b) Genetic polymorphisms
c) Renal function
d) Hepatic enzyme activity
ANSs : a) Age of the patient, b) Genetic polymorphisms, d)
Hepatic enzyme activity
Rationale : Age, genetic variability, and enzyme activity
influence drug metabolism, while renal function affects drug
excretion.
---
5. Multiple Choice
©2025
, Question : Which drug class is commonly used as the first-line
treatment for hypertension in patients with diabetes?
a) Beta blockers
b) Thiazide diuretics
c) Angiotensin-converting enzyme (ACE) inhibitors
d) Calcium channel blockers
ANS : c) Angiotensin-converting enzyme (ACE) inhibitors
Rationale : ACE inhibitors are preferred for diabetic patients
because they protect against renal damage in addition to reducing
blood pressure.
---
6. Fill-in-the-Blank
Question : The maximum effect a drug can produce, regardless
of dose, is referred to as __________.
ANS : Efficacy
Rationale : Efficacy describes a drug’s ability to achieve its
desired therapeutic effect, independent of dose.
---
©2025
Advanced Pharmacology
FA Review (Qns & Ans)
2025
1. Multiple Choice
Question : Which pharmacokinetic process refers to the
movement of a drug from the site of administration into the
bloodstream?
a) Absorption
b) Distribution
c) Metabolism
d) Excretion
©2025
, ANS : a) Absorption
Rationale : Absorption is the first pharmacokinetic process
through which a drug enters the bloodstream, allowing it to reach
systemic circulation.
---
2. Fill-in-the-Blank
Question : The __________ effect refers to the metabolism of a
drug by the liver before it reaches systemic circulation.
ANS : First-pass
Rationale : The first-pass effect occurs when oral medications
are metabolized in the liver, reducing the amount available for
systemic circulation.
---
3. True/False
Question : A narrow therapeutic index indicates that a drug is
safer and requires less monitoring.
ANS : False
©2025
, Rationale : Drugs with a narrow therapeutic index have a small
margin between therapeutic and toxic doses, requiring careful
monitoring.
---
4. Multiple Response
Question : Which factors affect drug metabolism in the liver?
a) Age of the patient
b) Genetic polymorphisms
c) Renal function
d) Hepatic enzyme activity
ANSs : a) Age of the patient, b) Genetic polymorphisms, d)
Hepatic enzyme activity
Rationale : Age, genetic variability, and enzyme activity
influence drug metabolism, while renal function affects drug
excretion.
---
5. Multiple Choice
©2025
, Question : Which drug class is commonly used as the first-line
treatment for hypertension in patients with diabetes?
a) Beta blockers
b) Thiazide diuretics
c) Angiotensin-converting enzyme (ACE) inhibitors
d) Calcium channel blockers
ANS : c) Angiotensin-converting enzyme (ACE) inhibitors
Rationale : ACE inhibitors are preferred for diabetic patients
because they protect against renal damage in addition to reducing
blood pressure.
---
6. Fill-in-the-Blank
Question : The maximum effect a drug can produce, regardless
of dose, is referred to as __________.
ANS : Efficacy
Rationale : Efficacy describes a drug’s ability to achieve its
desired therapeutic effect, independent of dose.
---
©2025
