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Serum Albumin - ✔✔3.5-5.0 g/dl
visceral protein
maintains colloidal osmotic pressure
hypoalbumiemia associated with edema, surgery
levels above range likely do to dehydration
long half-life, doesn't reflect current protein intake
Serum Transferrin - ✔✔>200 mg/dl
visceral protein that transports iron to bone marrow for production of
hemoglobin.
serum levels controlled by iron storage pool
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,levels rise with iron deficiency. transferrin synthesis
can be determined by TIBC= total iron binding capacity
TTHY
PAB - ✔✔Transthyretin, Prealbumin
16-40 mg/dl
Is considered best visceral protein to evaluate
short half-life; detects changes in protein status quickly
during inflammation. liver synthesizes CRP at expense of PAB
RBP - ✔✔Retinol-Binding Protein
3-6 mg/dl
circulates with prealbumin, shortest half-life (12 hrs)
binds and transports retinol
HCT - ✔✔Hematocrit
M: 42-52% F: 35-47% preg: 33%
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,measures iron levels
volume of packed cells in whole blood
Hgb - ✔✔Hemoglobin
M:14-17 gm/dl F: 12-15 gm/dl preg: <11
iron-containing pigment of red blood cells
erythrocytes are produced in bone marrow
Serum Ferritin - ✔✔M: 12-300 ng/ml F:10-150 ng/ml
indicates size of iron storage pool
Serum Creatinine - ✔✔0.6-1.4 mg/dl
related to muscle mass, measures somatic protein
may indicate renal disease, muscle wasting
(serum creatinine + BUN = kidney fx)
CHI - ✔✔Creatinine Height Index
80% normal
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, ratio of creatinine excreted/24 hours to height
estimates lean body mass-somatic protein
60-80% mild muscle depletion
BUN - ✔✔Blood Urea Nitrogen
10-20 mg/dl
related to protein intake
indicator of renal disease
BUN: creatinine ratio normal: 10-15:1
Urinary Creatinine Clearance - ✔✔115 +_ 20 ml/minute
measures GFR- glomerular filtration, renal fx
estimate includes body surface area (ht and wt)
TLC - ✔✔Total Lymphocyte count
>2700 cells/cu mm
measures immunocompetency
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