NURS 5334 Exam 2 UPDATED Exam Questions and CORRECT Answers

NURS 5334 Exam 2 UPDATED Exam
Questions and CORRECT Answers
What are the neurotransmitters of the PNS - CORRECT ANSWER - Acetylcholine
(mediates cholinergic receptors)
Norepinephrine/epinephrine (mediate adrenergic receptors)


Cholinergic receptor subtypes - CORRECT ANSWER - nicotinic and muscarinic



Adrenergic receptor subtypes - CORRECT ANSWER - alpha 1, alpha 2, beta 1, beta 2



Alpha 1 receptor functions - CORRECT ANSWER - vasoconstriction
ejaculation
contraction of bladder neck & prostate


Alpha 2 receptor function - CORRECT ANSWER - little clinical significance



Beta 1 receptor functions - CORRECT ANSWER - Heart (increase rate and force of
contraction)
Kidney (renin release)
Conduction of the AV node


Beta 2 receptor functions - CORRECT ANSWER - Bronchial dilation
relaxation of uterine muscle
vasodilation
glycogenolysis


Dopamine function - CORRECT ANSWER - dilates renal blood vessels

,Without subtypes - CORRECT ANSWER - a drug that acts on one site will alter all sites



Cholinergic drugs function to - CORRECT ANSWER - Turn on PNS



Muscarinic Agonists function - CORRECT ANSWER - mimic the effects of acetylcholine
at muscarinic receptors


Bethanechol function - CORRECT ANSWER - constricts bronchi, increase GI tone and
motility, contraction of detrusor muscle and relaxes trigone and sphincter


Bethanechol used for - CORRECT ANSWER - urinary retention



bethanechol adverse effects - CORRECT ANSWER - hypotension, abd cramps/diarrhea,
increased salivation, asthma exacerbation


Cevimeline - CORRECT ANSWER - treats dry mouth in Sjogren Syndrome



Pilocarpine - CORRECT ANSWER - topical therapy for glaucoma



Acetylcholine - CORRECT ANSWER - Used for mitosis (pupil constriction) after cataract
surgery


Muscarinic poisoning treated with - CORRECT ANSWER - atropine



Drugs that turn off PNS - CORRECT ANSWER - Muscarinic antagonists
(parasympatholytic drugs, antimuscarinic drugs, muscarinic blockers, anticholinergic drugs)

,Muscarinic antagonists function - CORRECT ANSWER - selectively block the effects
acetylcholine at muscarinic receptors


Muscarinic antagonists are also known as - CORRECT ANSWER - parasympatholytic
drugs, antimuscarinic drugs, muscarinic blockers or anticholinergic drugs


Atropine function - CORRECT ANSWER - Increases HR
Decrease secretions
relax bronchi
decrease tone of detrusor
decrease tone & motility of GI
mydriasis (pupil dilation)


Atropine uses - CORRECT ANSWER - preanesthetic
eye disorders
bradycardia
intestinal hypermotility
asthma
muscarinic agonist poisoning


Atropine side effects - CORRECT ANSWER - dry mouth
blurred vision
increase IOP
urinary retention
constipation
tachycardia
asthma

, Atropine can me used to treat _______ but can also worse _______ by thickening and drying
bronchial secretions causing plugging - CORRECT ANSWER - Asthma



Anticholinergic drugs for overactive bladder - CORRECT ANSWER - oxybutynin
(Ditropan)
Darifenacin
Solifenacin
Tolterodine
Fesorterodine
Trospium


Oxybutynin (Ditropan) - CORRECT ANSWER - anticholinergic side effects



Darifenacin - CORRECT ANSWER - greatest M3 selectivity
can reduce OAB symptoms while having no effects of M1 receptors in brain or M2 receptors in
the heart


Darifenacin can cause - CORRECT ANSWER - dry mouth and constipation



Solifenacin - CORRECT ANSWER - similar to darifenacin but can cause prolonged QT at
high doses


Tolterodine - CORRECT ANSWER - nonselevtive
fewer anticholinergic effects
prolongs QT


Fesoterodine & Trospium - CORRECT ANSWER - nonselective



Scopolamine - CORRECT ANSWER - Muscarinic Antagonist