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acetaminophen brand - ✔✔Tylenol
acetaminophen drug class - ✔✔analgesic/antipyretic
acetaminophen indications - ✔✔analgesia, fever
acetaminophen dose/route - ✔✔IR: 325-650 mg PO/PR q4h
ER: 1000 mg PO q6-8h
acetaminophen MOA - ✔✔- produces antipyresis at hypothalamus
- blocks peripheral impulse generation
- inhibits prostaglandin synthesis in CNS
acetaminophen 3 adverse effects - ✔✔- angioedema
- disorientation/dizziness
- pruritic, maculopapular rash
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,acetaminophen elimination - ✔✔hepatic metabolism, excreted in urine
acetaminophen is in what pregnancy category? what does this mean? - ✔✔- category B
- no risk in animal studies, no human studies
avoid doses greater than _______ mg daily of acetaminophen - ✔✔3250 mg
amlodipine brand - ✔✔Norvasc
amlodipine drug class - ✔✔antihypertensive
amlodipine indications - ✔✔hypertension, coronary heart disease, angina
amlodipine dose/route - ✔✔5 mg PO daily, may increase to q7-14 days *do not exceed
10 mg PO daily*
amlodipine MOA - ✔✔- calcium channel blocker
- inhibits cardiac and vascular smooth muscle contraction
- dilation of main coronary and systemic arteries
3 adverse effects of amlodipine - ✔✔- edema/pulmonary edema
- headache
- fatigue
elimination of amlodipine - ✔✔hepatic metabolism, excreted in urine
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,what 5 drugs does amlodipine come in combination with? - ✔✔- benazepril
- atorvastatin
- olmesartan
- telmisartan
- valsartan
amlodipine should be used with caution in patients with ______ - ✔✔CHF
peripheral edema caused by amlodipine can take how long to develop? - ✔✔2-3 weeks
amlodipine should be titrated slowly in patients with what? why? - ✔✔severe hepatic
impairment due to extensive liver metabolism
aspirin brand name - ✔✔Bayer aspirin
aspirin drug class - ✔✔salicylate, antiplatelet
indications for aspirin - ✔✔pain, fever, acute coronary syndrome
aspirin dose/route - ✔✔325-650 mg PO/PR q4-6h PRN
ACS: 160-325 mg PO, chew nonenteric-coated tablet, 81-325 mg daily maintenance
aspirin MOA - ✔✔- blocks COX inhibits synthesis of prostaglandins
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, - inhibits platelet aggregation
- antipyretic and analgesic
3 adverse effects of aspirin - ✔✔- angioedema, urtucaria, rash
- bronchospasm
- CNS alteration
elimination of aspirin - ✔✔hepatic metabolism, excreted in urine, sweat, saliva and
feces
8 contraindications of aspirin - ✔✔- bleeding GI ulcers
- hemophilia
- hemorrhoids
- lactating mothers
- nasal polyps with asthma
- sarcoidosis
- thrombocytopenia
- ulcerative colitis
avoid using aspirin in pediatric patients due to ________ - ✔✔Reyes syndrome
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