FL 5 AAMC MCAT STANDARDIZED EXAM 2025/2026
QUESTIONS WITH SOLUTIONS GRADED A+
✔✔What is the name of the ionic compound used to make Buffer B?
A.
Ammonium formate
B.
Ammonium carbonate
C.
Ammonium bicarbonate
D.
Ammonium acetate - ✔✔formate: hco2
carbonate: Hco3-
bicarbonate: hco3-
acetate: ch3cooh
✔✔Which chromatographic technique would most likely separate a mixture of native
carbonic anhydrase from carbonic anhydrase photochemically modified by CCl3CO2H?
- ✔✔Passage says: Native carbonic anhydrase also has a net charge of -2.9 at pH 8.0.
The photochemical adds carboxylic acids which are negatively charged
✔✔Pv=nrt - ✔✔Helps you look at the relationship between everything
4 mols of CO react to give you 2 mol of product
n is halved that mean pressure is halved bc direct relationship
0.5*1
✔✔In which phase(s) will the MCS precursor be predominantly found after the
extraction step? - ✔✔Passage MCS is a lipophillic precursor (it loves lipids) so it is not
water soluble
✔✔When the covalent attachment to alliinase is broken, PLP is still held rigidly in the
active site by a salt bridge and a π-stacking interaction. These interactions are most
likely provided by the side chains of which amino acids? - ✔✔Can eliminate B and D
because they do not include pi stacking (tyrosine pi stacks)
Now between Asp and Arg. Use passage info
Alliinase is a pyridoxal phosphate (PLP, vitamin B6) dependent enzyme. PLP is a planar
molecule with a 6-membered ring, a hydroxyl group, an aldehyde group, and a
phosphate. PLP is covalently attached to alliinase by forming an aldimine with the side
chain of the amino acid at position 251.
So negative needs a positive to stabilize (phosphate in the group when deprotonated
would be negative)
✔✔As the pH of a solution of this amino acid is raised, which group deprotonates first? -
✔✔Between I and III
, I would be more acidic because the negative charged is stabilized through inductive
effect of the neighboring electronegative chlorines
In the case of III the negative charge would be unstable because of the close charge
seaparation from the amino group
✔✔units for capacitance - ✔✔farad
✔✔If both the capacitor and the power supply in Figure 1 are adjustable, which of the
following changes would result in an increase in the charge on the capacitor?
Jack Westin Advanced Solution will be added here.
A.
Decreasing the area of the parallel plates
B.
Decreasing the separation between the parallel plates
C.
Removing the dielectric from the capacitor
D.
Decreasing the voltage of the power supply - ✔✔Q=CV and also C=AE0/D
Adding a dielectric will increase the capacitance and therefore decrease the energy
stored in a capacitor
✔✔If the wavelength of a light beam were doubled, its frequency would be: -
✔✔c=lambdaf
✔✔If the energy of a photon is doubled, which of the following properties of the photon
will also double? - ✔✔e=hc/lambda
e=hf
✔✔An ester is prepared by the method of direct esterification using an esterase enzyme
as a catalyst. Which of the following modifications will NOT appreciably increase the
final yield of ester? - ✔✔B. increase on reactant will shift to products
C. increase in reactants will shift to products
D. removing product will cause product to freak out and get it
✔✔Question
A person pushes on a rolling cart with a force that diminishes with time because the
person must walk faster to keep up with the accelerating cart. How much work does the
person generate while pushing on the cart? - ✔✔area on force and distance graph=
work
✔✔The association observed experimentally between the expression of miRNAs and
mRNAs in AR kidney transplants indicates that miRNAs regulate the expression of
genes implicated in which type(s) of immune response(s)? - ✔✔I looked as passage
QUESTIONS WITH SOLUTIONS GRADED A+
✔✔What is the name of the ionic compound used to make Buffer B?
A.
Ammonium formate
B.
Ammonium carbonate
C.
Ammonium bicarbonate
D.
Ammonium acetate - ✔✔formate: hco2
carbonate: Hco3-
bicarbonate: hco3-
acetate: ch3cooh
✔✔Which chromatographic technique would most likely separate a mixture of native
carbonic anhydrase from carbonic anhydrase photochemically modified by CCl3CO2H?
- ✔✔Passage says: Native carbonic anhydrase also has a net charge of -2.9 at pH 8.0.
The photochemical adds carboxylic acids which are negatively charged
✔✔Pv=nrt - ✔✔Helps you look at the relationship between everything
4 mols of CO react to give you 2 mol of product
n is halved that mean pressure is halved bc direct relationship
0.5*1
✔✔In which phase(s) will the MCS precursor be predominantly found after the
extraction step? - ✔✔Passage MCS is a lipophillic precursor (it loves lipids) so it is not
water soluble
✔✔When the covalent attachment to alliinase is broken, PLP is still held rigidly in the
active site by a salt bridge and a π-stacking interaction. These interactions are most
likely provided by the side chains of which amino acids? - ✔✔Can eliminate B and D
because they do not include pi stacking (tyrosine pi stacks)
Now between Asp and Arg. Use passage info
Alliinase is a pyridoxal phosphate (PLP, vitamin B6) dependent enzyme. PLP is a planar
molecule with a 6-membered ring, a hydroxyl group, an aldehyde group, and a
phosphate. PLP is covalently attached to alliinase by forming an aldimine with the side
chain of the amino acid at position 251.
So negative needs a positive to stabilize (phosphate in the group when deprotonated
would be negative)
✔✔As the pH of a solution of this amino acid is raised, which group deprotonates first? -
✔✔Between I and III
, I would be more acidic because the negative charged is stabilized through inductive
effect of the neighboring electronegative chlorines
In the case of III the negative charge would be unstable because of the close charge
seaparation from the amino group
✔✔units for capacitance - ✔✔farad
✔✔If both the capacitor and the power supply in Figure 1 are adjustable, which of the
following changes would result in an increase in the charge on the capacitor?
Jack Westin Advanced Solution will be added here.
A.
Decreasing the area of the parallel plates
B.
Decreasing the separation between the parallel plates
C.
Removing the dielectric from the capacitor
D.
Decreasing the voltage of the power supply - ✔✔Q=CV and also C=AE0/D
Adding a dielectric will increase the capacitance and therefore decrease the energy
stored in a capacitor
✔✔If the wavelength of a light beam were doubled, its frequency would be: -
✔✔c=lambdaf
✔✔If the energy of a photon is doubled, which of the following properties of the photon
will also double? - ✔✔e=hc/lambda
e=hf
✔✔An ester is prepared by the method of direct esterification using an esterase enzyme
as a catalyst. Which of the following modifications will NOT appreciably increase the
final yield of ester? - ✔✔B. increase on reactant will shift to products
C. increase in reactants will shift to products
D. removing product will cause product to freak out and get it
✔✔Question
A person pushes on a rolling cart with a force that diminishes with time because the
person must walk faster to keep up with the accelerating cart. How much work does the
person generate while pushing on the cart? - ✔✔area on force and distance graph=
work
✔✔The association observed experimentally between the expression of miRNAs and
mRNAs in AR kidney transplants indicates that miRNAs regulate the expression of
genes implicated in which type(s) of immune response(s)? - ✔✔I looked as passage
