Phrm 515 Exam 2 Already Passed
dimethyl sulfoxide - =Universal solvent in pharma
changes keratin from a to b sheet
extracts lipids from corneum
ethanol - =most commonly used alcohol
extracts corneum lipids
Aerosol system - =container valve propellant
What is the most widely used container - =tin-plated steel
What are propellants? - =Compressed gases, liquefied gases
issue with compressed gases - =lose pressure over time
Benefit of HFA - =no impact on ozone layer
low toxicity
high stability
pure
ways to fill an aresol - =cold filling
pressure filling
What is a metered dose inhaler? - =most common aerosol
What is a dry powder inhalation good for - =large macro molecule
, Why did exubera (inhaled insulin) fail - =too big too expensive not effective
Types of polymers - =Natural, Synthetic, Semi synthetic
natural polymers - =starch, cellulose, proteins
Synthetic polymers - =polymers that are made from petroleum products and are long polymers
semi-synthetic polymers - =mostly derived from naturally occurring polymers by chemical
modifications
Natural bio-degradable polymers - =Tend to be more impure and expensive
Synthetic bio-degradable polymers - =preferred
Linear polymers - =no branching or cross-links
branched polymer - =A polymer having a molecular structure of secondary chains that extend
from the primary main chains.
3 or more functional groups
Polymerization - =joining monomers to form a polymer
initiator - =relatively unstable and decomposes into a free radical
propagation - =middle step in chain polymerization monomers are attached
Termination - =reaction ended propagation of chain
dimethyl sulfoxide - =Universal solvent in pharma
changes keratin from a to b sheet
extracts lipids from corneum
ethanol - =most commonly used alcohol
extracts corneum lipids
Aerosol system - =container valve propellant
What is the most widely used container - =tin-plated steel
What are propellants? - =Compressed gases, liquefied gases
issue with compressed gases - =lose pressure over time
Benefit of HFA - =no impact on ozone layer
low toxicity
high stability
pure
ways to fill an aresol - =cold filling
pressure filling
What is a metered dose inhaler? - =most common aerosol
What is a dry powder inhalation good for - =large macro molecule
, Why did exubera (inhaled insulin) fail - =too big too expensive not effective
Types of polymers - =Natural, Synthetic, Semi synthetic
natural polymers - =starch, cellulose, proteins
Synthetic polymers - =polymers that are made from petroleum products and are long polymers
semi-synthetic polymers - =mostly derived from naturally occurring polymers by chemical
modifications
Natural bio-degradable polymers - =Tend to be more impure and expensive
Synthetic bio-degradable polymers - =preferred
Linear polymers - =no branching or cross-links
branched polymer - =A polymer having a molecular structure of secondary chains that extend
from the primary main chains.
3 or more functional groups
Polymerization - =joining monomers to form a polymer
initiator - =relatively unstable and decomposes into a free radical
propagation - =middle step in chain polymerization monomers are attached
Termination - =reaction ended propagation of chain
