PHARMACOLOGY EVOLVE HESI WITH
EXAM WITH COMPLETE SOLUTIONS
A b19-year-old bmale bclient bwho bhas bsustained ba bsevere bhead binjury bis bintubated
band bplaced bon bassisted bmechanical bventilation. bTo bfacilitate boptimal bventilation
band bprevent bthe bclient bfrom b"fighting" bthe bventilator, bthe bhealth bcare bprovider
badministers bpancuronium bbromide bIV, bwith badjunctive bopioid banalgesia. bWhat
bmedication bshould bbe bimmediately baccessible bfor ba bpotential bcomplication bwith
bthis bdrug?
A. bDantrolene bsodium
B. bNeostigmine bbromide
C. bSuccinylcholine bbromide
D. bEpinephrine b- bcorrect banswers b-B. bNeostigmine bbromide
,Neostigmine bbromide band batropine bsulfate, bboth banticholinergic bdrugs, breverse
bthe brespiratory bmuscle bparalysis bcaused bby bpancuronium bbromide. bOptions bA,
bC, band bD bare bnot bantagonists bto bpancuronium bbromide band bwould bnot bbe
bhelpful bin breversing bthe beffects bof bthe bdrug bcompared bwith bthe buse bof
banticholinergics.
A bclient bwith bviral binfluenza bis breceiving bvitamin bC, b1000 bmg bPO bdaily, band
bacetaminophen belixir, b650 bmg bPO bevery b4 bhours bPRN. bThe bnurse bcalls bthe
bhealth bcare bprovider bto breport bthat bthe bclient bhas bdeveloped bdiarrhea. bWhich
bchange bin bprescriptions bshould bthe bnurse banticipate?
A. bChange bthe bacetaminophen bto bibuprofen.
B. bChange bthe belixir bto ban binjectable broute.
C. bDecrease bthe bdose bof bvitamin bC.
D. bBegin btreatment bwith ban bantibiotic. b- bcorrect banswers b-C. bDecrease bthe bdose
bof bvitamin bC.
When bproviding bnursing bcare bfor ba bclient breceiving bpyridostigmine bbromide bfor
bmyasthenia bgravis, bwhich bnursing bintervention bhas bthe bhighest bpriority?
A. bMonitor bthe bclient bfrequently bfor burinary bretention.
B. bAssess brespiratory bstatus band bbreath bsounds boften.
C. bMonitor bblood bpressure beach bshift bto bscreen bfor bhypertension.
D. bAdminister bmost bmedications bafter bmeals bto bdecrease bgastrointestinal
birritation. b- bcorrect banswers b-B. bAssess brespiratory bstatus band bbreath bsounds
boften.
A bclient bwith ba bdislocated bshoulder bis bbeing bprepared bfor ba bclosed bmanual
breduction busing bconscious bsedation. bWhich bmedication bshould bthe bnurse bexplain
bas ba bsedative bused bduring bthe bprocedure?
A.Inhaled bnitrous boxide
B.Midazolam bIV
C.Ketamine bIM
D.Fentanyl band bdroperidol bIM b- bcorrect banswers b-B. bMidazolam bIV
A bclient bis bbeing bdischarged bwith ba bprescription bfor bsulfasalazine bto btreat
bulcerative bcolitis. bWhich binstruction bshould bthe bnurse bprovide bto bthis bclient bprior
bto bdischarge?
A. bMaintain bgood boral bhygiene.
B. bTake bthe bmedication b30 bminutes bbefore ba bmeal.
C. bDiscontinue buse bof bthe bdrug bgradually.
D. bDrink bat bleast beight bglasses bof bfluid ba bday. b- bcorrect banswers b-D. bDrink bat
bleast beight bglasses bof bfluid ba bday.
,The bhealth bcare bprovider bprescribes bcarbamazepine bfor ba bchild bwhose btonic-
clonic bseizures bhave bbeen bpoorly bcontrolled. bThe bnurse binforms bthe bmother bthat
bthe bchild bmust bhave bblood btests bevery bweek. bThe bmother basks bwhy bso bmany
bblood btests bare bnecessary. bWhich bcomplication bis bassessed bthrough bfrequent
blaboratory btesting bthat bthe bnurse bshould bexplain bto bthis bmother?
A. bNephrotoxicity
B. bOtotoxicity
C. bMyelosuppression
D.Hepatotoxicity b- bcorrect banswers b-C. bMyelosuppression
Myelosuppression bis bthe bhighest bpriority bcomplication bthat bcan bpotentially baffect
bclients bmanaged bwith bcarbamazepine btherapy. bThe bclient brequires bclose
bmonitoring bfor bthis bcondition bby bweekly blaboratory btesting. bHepatic bfunction bmay
bbe baltered, bbut bthis bcomplication bdoes bnot bhave bas bgreat ba bpotential bfor
boccurrence bas boption bC. bOptions bA band bB bare bnot btypical bcomplications bof
bcarbamazepine btherapy.
When bdeveloping ba bwritten bnursing bcare bplan bfor ba bclient breceiving
bchemotherapy bfor btreatment bof bcancer, bthe bnurse bwrites, b"Assess beach bvoiding
bfor bhematuria." bThe badministration bof bwhich btype bof bchemotherapeutic bagent
bwould bprompt bthe bnurse bto badd bthis bintervention?
A. bVincristine
B. bBleomycin bsulfate
C. bChlorambucil
D. bCyclophosphamide b- bcorrect banswers b-D. bCyclophosphamide
Hemorrhagic bcystitis bis bthe bcharacteristic badverse breaction bof bcyclophosphamide.
bAdministration bof boptions bA, bB, band bC bdoes bnot btypically bcause bhemorrhagic
bcystitis.
A bclient bis breceiving boral bgriseofulvin bfor ba bpersistent btinea bcorporis binfection.
bWhich bresponse bby bthe bclient bindicates ban baccurate bunderstanding bof bthe bdrug
bteaching bconducted bby bthe bnurse?
A. b"I'll bwear bsunscreen bwhenever bI bmow bthe blawn."
B. b"This bis bthe bworse bbacterial binfection bI've bever bhad."
C. b"I bwill bneed bto btake bthe bmedication bfor b7 bdays."
D. b"My burine bwill bprobably bturn bbrown bdue bto bthis bdrug." b- bcorrect banswers b-A.
b"I'll bwear bsunscreen bwhenever bI bmow bthe blawn."
Photosensitivity bis ba bside beffect bof bgriseofulvin, bso bclients bshould bbe bcautioned
bto bwear bprotective bsunscreen bduring bsun bexposure. bOptions bB, bC, band bD bare
bnot baccurate bstatements babout bside beffects bof bthis bmedication.
, A b6-year-old bchild bis badmitted bto bthe bemergency bdepartment bwith bstatus
bepilepticus. bHis bparents breport bthat bhis bseizure bdisorder bhas bbeen bmanaged
bwith bphenytoin, b50 bmg bPO bbid, bfor bthe bpast byear. bWhich bdrug bshould bthe
bnurse bplan bto badminister bin bthe bemergency bdepartment?
A. bPhenytoin
B. bDiazepam
C. bPhenobarbital
D. bCarbamazepine b- bcorrect banswers b-B. bDiazepam
Diazepam bis bthe bdrug bof bchoice bfor btreatment bof bstatus bepilepticus. bOptions bA,
bC, band bD bare bused bfor bthe blong-term bmanagement bof bseizure bdisorders bbut
bare bnot bas buseful bin bthe bemergency bmanagement bof bstatus bepilepticus.
A bclient bwho bhas btrouble bswallowing bpills bintermittently bhas bbeen bprescribed
bvenlafaxine b(XR) bfor bdepression. bThe bmedication bcomes bin bcapsule bform. bWhat
bshould bthe bnurse binclude bin bthe bdischarge bteaching bplan bfor bthis bclient?
A. bCapsule bcontents bcan bbe bsprinkled bon bpudding bor bapplesauce.
B. bChew bthe bmedication bthoroughly bto benhance babsorption.
C. bTake bthe bmedication bwith ba blarge bglass bof bwater bor bjuice.
D. bContact bthe bhealth bcare bprovider bfor banother bform bof bmedication. b- bcorrect
banswers b-D. bContact bthe bhealth bcare bprovider bfor banother bform bof bmedication.
Venlafaxine bis badministered bPO bin bcapsule bform. bCapsules bthat bare bextended-
release b(XR) bor bcontinuous-release b(CR) bcontain bdelayed-release, benteric-coated
bgranules bto bprevent bdecomposition bof bthe bdrug bin bthe bacidic bpH bof bthe
bstomach. bThe bclient bshould bnotify bthe bhealth bcare bprovider babout bthe binability
bto bswallow bthe bcapsule. bThis bmedication bshould bnot bbe bchewed bor bopened bso
bthat bthe bdelayed-release, benteric-coated bgranules bcan bremain bintact. bWater bor
bjuice bwill bnot baffect bthe bmedication.
The bnurse bis bpreparing bto bapply ba bsurface banesthetic bagent bfor ba bclient. bWhich
baction bshould bthe bnurse bimplement bto breduce bthe brisk bof bsystemic babsorption?
A. bApply bthe banesthetic bto bmucous bmembranes.
B. bLimit bthe barea bof bapplication bto binflamed bareas.
C. bAvoid babraded bskin bareas bwhen bapplying bthe banesthetic.
D. bSpread bthe btopical bagent bover ba blarge bsurface barea. b- bcorrect banswers b-C.
bAvoid babraded bskin bareas bwhen bapplying bthe banesthetic.
To bminimize bsystemic babsorption bof btopical banesthetics, bthe banesthetic bagent
bshould bbe bapplied bto bthe bsmallest bsurface barea bof bintact bskin. bApplication bto
bthe bmucous bmembranes bposes bthe bgreatest brisk bof bsystemic babsorption
bbecause babsorption boccurs bmore breadily bthrough bmucous bmembranes bthan
bthrough bthe bskin. bInflamed bareas bgenerally bhave ban bincreased bblood bsupply,
EXAM WITH COMPLETE SOLUTIONS
A b19-year-old bmale bclient bwho bhas bsustained ba bsevere bhead binjury bis bintubated
band bplaced bon bassisted bmechanical bventilation. bTo bfacilitate boptimal bventilation
band bprevent bthe bclient bfrom b"fighting" bthe bventilator, bthe bhealth bcare bprovider
badministers bpancuronium bbromide bIV, bwith badjunctive bopioid banalgesia. bWhat
bmedication bshould bbe bimmediately baccessible bfor ba bpotential bcomplication bwith
bthis bdrug?
A. bDantrolene bsodium
B. bNeostigmine bbromide
C. bSuccinylcholine bbromide
D. bEpinephrine b- bcorrect banswers b-B. bNeostigmine bbromide
,Neostigmine bbromide band batropine bsulfate, bboth banticholinergic bdrugs, breverse
bthe brespiratory bmuscle bparalysis bcaused bby bpancuronium bbromide. bOptions bA,
bC, band bD bare bnot bantagonists bto bpancuronium bbromide band bwould bnot bbe
bhelpful bin breversing bthe beffects bof bthe bdrug bcompared bwith bthe buse bof
banticholinergics.
A bclient bwith bviral binfluenza bis breceiving bvitamin bC, b1000 bmg bPO bdaily, band
bacetaminophen belixir, b650 bmg bPO bevery b4 bhours bPRN. bThe bnurse bcalls bthe
bhealth bcare bprovider bto breport bthat bthe bclient bhas bdeveloped bdiarrhea. bWhich
bchange bin bprescriptions bshould bthe bnurse banticipate?
A. bChange bthe bacetaminophen bto bibuprofen.
B. bChange bthe belixir bto ban binjectable broute.
C. bDecrease bthe bdose bof bvitamin bC.
D. bBegin btreatment bwith ban bantibiotic. b- bcorrect banswers b-C. bDecrease bthe bdose
bof bvitamin bC.
When bproviding bnursing bcare bfor ba bclient breceiving bpyridostigmine bbromide bfor
bmyasthenia bgravis, bwhich bnursing bintervention bhas bthe bhighest bpriority?
A. bMonitor bthe bclient bfrequently bfor burinary bretention.
B. bAssess brespiratory bstatus band bbreath bsounds boften.
C. bMonitor bblood bpressure beach bshift bto bscreen bfor bhypertension.
D. bAdminister bmost bmedications bafter bmeals bto bdecrease bgastrointestinal
birritation. b- bcorrect banswers b-B. bAssess brespiratory bstatus band bbreath bsounds
boften.
A bclient bwith ba bdislocated bshoulder bis bbeing bprepared bfor ba bclosed bmanual
breduction busing bconscious bsedation. bWhich bmedication bshould bthe bnurse bexplain
bas ba bsedative bused bduring bthe bprocedure?
A.Inhaled bnitrous boxide
B.Midazolam bIV
C.Ketamine bIM
D.Fentanyl band bdroperidol bIM b- bcorrect banswers b-B. bMidazolam bIV
A bclient bis bbeing bdischarged bwith ba bprescription bfor bsulfasalazine bto btreat
bulcerative bcolitis. bWhich binstruction bshould bthe bnurse bprovide bto bthis bclient bprior
bto bdischarge?
A. bMaintain bgood boral bhygiene.
B. bTake bthe bmedication b30 bminutes bbefore ba bmeal.
C. bDiscontinue buse bof bthe bdrug bgradually.
D. bDrink bat bleast beight bglasses bof bfluid ba bday. b- bcorrect banswers b-D. bDrink bat
bleast beight bglasses bof bfluid ba bday.
,The bhealth bcare bprovider bprescribes bcarbamazepine bfor ba bchild bwhose btonic-
clonic bseizures bhave bbeen bpoorly bcontrolled. bThe bnurse binforms bthe bmother bthat
bthe bchild bmust bhave bblood btests bevery bweek. bThe bmother basks bwhy bso bmany
bblood btests bare bnecessary. bWhich bcomplication bis bassessed bthrough bfrequent
blaboratory btesting bthat bthe bnurse bshould bexplain bto bthis bmother?
A. bNephrotoxicity
B. bOtotoxicity
C. bMyelosuppression
D.Hepatotoxicity b- bcorrect banswers b-C. bMyelosuppression
Myelosuppression bis bthe bhighest bpriority bcomplication bthat bcan bpotentially baffect
bclients bmanaged bwith bcarbamazepine btherapy. bThe bclient brequires bclose
bmonitoring bfor bthis bcondition bby bweekly blaboratory btesting. bHepatic bfunction bmay
bbe baltered, bbut bthis bcomplication bdoes bnot bhave bas bgreat ba bpotential bfor
boccurrence bas boption bC. bOptions bA band bB bare bnot btypical bcomplications bof
bcarbamazepine btherapy.
When bdeveloping ba bwritten bnursing bcare bplan bfor ba bclient breceiving
bchemotherapy bfor btreatment bof bcancer, bthe bnurse bwrites, b"Assess beach bvoiding
bfor bhematuria." bThe badministration bof bwhich btype bof bchemotherapeutic bagent
bwould bprompt bthe bnurse bto badd bthis bintervention?
A. bVincristine
B. bBleomycin bsulfate
C. bChlorambucil
D. bCyclophosphamide b- bcorrect banswers b-D. bCyclophosphamide
Hemorrhagic bcystitis bis bthe bcharacteristic badverse breaction bof bcyclophosphamide.
bAdministration bof boptions bA, bB, band bC bdoes bnot btypically bcause bhemorrhagic
bcystitis.
A bclient bis breceiving boral bgriseofulvin bfor ba bpersistent btinea bcorporis binfection.
bWhich bresponse bby bthe bclient bindicates ban baccurate bunderstanding bof bthe bdrug
bteaching bconducted bby bthe bnurse?
A. b"I'll bwear bsunscreen bwhenever bI bmow bthe blawn."
B. b"This bis bthe bworse bbacterial binfection bI've bever bhad."
C. b"I bwill bneed bto btake bthe bmedication bfor b7 bdays."
D. b"My burine bwill bprobably bturn bbrown bdue bto bthis bdrug." b- bcorrect banswers b-A.
b"I'll bwear bsunscreen bwhenever bI bmow bthe blawn."
Photosensitivity bis ba bside beffect bof bgriseofulvin, bso bclients bshould bbe bcautioned
bto bwear bprotective bsunscreen bduring bsun bexposure. bOptions bB, bC, band bD bare
bnot baccurate bstatements babout bside beffects bof bthis bmedication.
, A b6-year-old bchild bis badmitted bto bthe bemergency bdepartment bwith bstatus
bepilepticus. bHis bparents breport bthat bhis bseizure bdisorder bhas bbeen bmanaged
bwith bphenytoin, b50 bmg bPO bbid, bfor bthe bpast byear. bWhich bdrug bshould bthe
bnurse bplan bto badminister bin bthe bemergency bdepartment?
A. bPhenytoin
B. bDiazepam
C. bPhenobarbital
D. bCarbamazepine b- bcorrect banswers b-B. bDiazepam
Diazepam bis bthe bdrug bof bchoice bfor btreatment bof bstatus bepilepticus. bOptions bA,
bC, band bD bare bused bfor bthe blong-term bmanagement bof bseizure bdisorders bbut
bare bnot bas buseful bin bthe bemergency bmanagement bof bstatus bepilepticus.
A bclient bwho bhas btrouble bswallowing bpills bintermittently bhas bbeen bprescribed
bvenlafaxine b(XR) bfor bdepression. bThe bmedication bcomes bin bcapsule bform. bWhat
bshould bthe bnurse binclude bin bthe bdischarge bteaching bplan bfor bthis bclient?
A. bCapsule bcontents bcan bbe bsprinkled bon bpudding bor bapplesauce.
B. bChew bthe bmedication bthoroughly bto benhance babsorption.
C. bTake bthe bmedication bwith ba blarge bglass bof bwater bor bjuice.
D. bContact bthe bhealth bcare bprovider bfor banother bform bof bmedication. b- bcorrect
banswers b-D. bContact bthe bhealth bcare bprovider bfor banother bform bof bmedication.
Venlafaxine bis badministered bPO bin bcapsule bform. bCapsules bthat bare bextended-
release b(XR) bor bcontinuous-release b(CR) bcontain bdelayed-release, benteric-coated
bgranules bto bprevent bdecomposition bof bthe bdrug bin bthe bacidic bpH bof bthe
bstomach. bThe bclient bshould bnotify bthe bhealth bcare bprovider babout bthe binability
bto bswallow bthe bcapsule. bThis bmedication bshould bnot bbe bchewed bor bopened bso
bthat bthe bdelayed-release, benteric-coated bgranules bcan bremain bintact. bWater bor
bjuice bwill bnot baffect bthe bmedication.
The bnurse bis bpreparing bto bapply ba bsurface banesthetic bagent bfor ba bclient. bWhich
baction bshould bthe bnurse bimplement bto breduce bthe brisk bof bsystemic babsorption?
A. bApply bthe banesthetic bto bmucous bmembranes.
B. bLimit bthe barea bof bapplication bto binflamed bareas.
C. bAvoid babraded bskin bareas bwhen bapplying bthe banesthetic.
D. bSpread bthe btopical bagent bover ba blarge bsurface barea. b- bcorrect banswers b-C.
bAvoid babraded bskin bareas bwhen bapplying bthe banesthetic.
To bminimize bsystemic babsorption bof btopical banesthetics, bthe banesthetic bagent
bshould bbe bapplied bto bthe bsmallest bsurface barea bof bintact bskin. bApplication bto
bthe bmucous bmembranes bposes bthe bgreatest brisk bof bsystemic babsorption
bbecause babsorption boccurs bmore breadily bthrough bmucous bmembranes bthan
bthrough bthe bskin. bInflamed bareas bgenerally bhave ban bincreased bblood bsupply,
