Immunohematology Exam Questions with Correct Answers Latest Update 2025 Graded A+
A patient has an anti-K antibody and an anti-C antibody. The doctor needs to transfuse two (2) units of
blood to the patient. How many units of blood will you have to screen to find two units that are negative
for both the K antigen and the C antigen given the following gene frequencies?,10% K positive 90% K
negative,70% C positive 30% C negative - Answers 8
A female patient is having a C-section. The doctor orders two units of blood to be Type and Screened.
The antibody screen shows that the mother has an anti-K antibody. If K and k are the possible alleles at a
specific locus on the chromosome, what is the woman's genotype? - Answers kk
One cat carries heterozygous, long-haired traits (Ss), and its mate carries homozygous short-haired traits
(ss). Use a Punnett square to determine the probability of one of their offspring having short hair. -
Answers 50%
One flower is heterozygous red (Rr) and it is crossed with a homozygous white (rr) plant. Use a Punnett
square to determine the probability of one of their offspring having a red color. - Answers 50%
A woman who is blood group B has a baby who is blood group AB. Her husband is blood group A. Can he
be the possible father of the child? - Answers Yes
Anti-A (4+), Anti-B (0), Anti-A,B (4+), A1 cells (0), B cells (4+) - Answers A
Anti-A (0), Anti-B (0), Anti-A,B (0), A1 cells (4+), B cells (4+) - Answers O
Anti-A (0), Anti-B (4+), Anti-A,B (4+), A1 cells (4+), B cells (0) - Answers B
Anti-A (4+), Anti-B (4+), Anti-A,B (4+), A1 cells (0), B cells (0) - Answers AB
Anti-A (0), Anti-B (0), Anti-A,B (0), A1 cells (0), B cells (0) - Answers The patient is elderly causing a
decrease in antibodies.
When a patient has formed an antibody against a red cell antigen: - Answers the antigen is lacking on
the patients RBC
What are the possible ABO phenotypes of the offspring from the mating of a group A to a group B
individual - Answers O A, B, AB
In grading of an agglutination reaction, a reaction of no aggregates would be classified as what? -
Answers
Phenotype is defined as the genetic characteristics which are: - Answers observable
Alternative forms that occupy a single locus are called: - Answers alleles
A group AO man marries a group BO woman. What are the possible ABO groups of their children? -
Answers A, B, O, AB
, When observing an agglutination reaction, if the red cell button breaks into several large aggregates
with a clear supernatant background, it is recorded as a: - Answers 3+ reaction
The force of repulsion between the red cells in a physiologic saline solution is called: - Answers zeta
potential
While performing an antibody screen on a patient, you accidentally put four drops of patient plasma
into the tubes instead of two drops. This may result in false negative agglutination because of: - Answers
prozone
This test detects antibody that is already attached to red blood cells in vivo (in the body). - Answers
Direct Antiglobulin Test
Which test detects antibody in plasma? - Answers Indirect Antiglobulin Test
A mother who is group AB delivered a baby who is group A. The husband is Group O. Can the husband
be the father of the child? - Answers yes
A mother who is group A delivered a group AB baby. The husband is group AB. Is it possible for the
husband to be the father of the child? - Answers yes
Molecules that bind to an antigen to enhance phagocytosis are: - Answers Opsonins
Antibodies are produced by: - Answers B cells
A red cell antigen is: - Answers on the red cell membrane.
Which of the following describes the expression of most blood group inheritance? - Answers
Codominant
A gene that produces no detectable product is referred to as: - Answers an amorphic gene
A gene that is inherited in "trans" position to another gene is: - Answers on an opposite chromosome.
The CD designation used in Immunology refers to: - Answers Clusters of Differentiation
Which lymphocytes are considered T-helper cells? - Answers CD4 cells
"Humoral" immunity refers to: - Answers production of antibodies.
Lysis of RBCs in the circulation due to a transfusion reaction is caused by: - Answers activation of
complement by antigen-antibody complexes.
Recruitment of additional phagocytic cells to the site of antigen-antibody reaction is caused by: -
Answers Chemotaxins
Units of inheritance that produce antigens on Red Blood Cells are called: - Answers Genes
A patient has an anti-K antibody and an anti-C antibody. The doctor needs to transfuse two (2) units of
blood to the patient. How many units of blood will you have to screen to find two units that are negative
for both the K antigen and the C antigen given the following gene frequencies?,10% K positive 90% K
negative,70% C positive 30% C negative - Answers 8
A female patient is having a C-section. The doctor orders two units of blood to be Type and Screened.
The antibody screen shows that the mother has an anti-K antibody. If K and k are the possible alleles at a
specific locus on the chromosome, what is the woman's genotype? - Answers kk
One cat carries heterozygous, long-haired traits (Ss), and its mate carries homozygous short-haired traits
(ss). Use a Punnett square to determine the probability of one of their offspring having short hair. -
Answers 50%
One flower is heterozygous red (Rr) and it is crossed with a homozygous white (rr) plant. Use a Punnett
square to determine the probability of one of their offspring having a red color. - Answers 50%
A woman who is blood group B has a baby who is blood group AB. Her husband is blood group A. Can he
be the possible father of the child? - Answers Yes
Anti-A (4+), Anti-B (0), Anti-A,B (4+), A1 cells (0), B cells (4+) - Answers A
Anti-A (0), Anti-B (0), Anti-A,B (0), A1 cells (4+), B cells (4+) - Answers O
Anti-A (0), Anti-B (4+), Anti-A,B (4+), A1 cells (4+), B cells (0) - Answers B
Anti-A (4+), Anti-B (4+), Anti-A,B (4+), A1 cells (0), B cells (0) - Answers AB
Anti-A (0), Anti-B (0), Anti-A,B (0), A1 cells (0), B cells (0) - Answers The patient is elderly causing a
decrease in antibodies.
When a patient has formed an antibody against a red cell antigen: - Answers the antigen is lacking on
the patients RBC
What are the possible ABO phenotypes of the offspring from the mating of a group A to a group B
individual - Answers O A, B, AB
In grading of an agglutination reaction, a reaction of no aggregates would be classified as what? -
Answers
Phenotype is defined as the genetic characteristics which are: - Answers observable
Alternative forms that occupy a single locus are called: - Answers alleles
A group AO man marries a group BO woman. What are the possible ABO groups of their children? -
Answers A, B, O, AB
, When observing an agglutination reaction, if the red cell button breaks into several large aggregates
with a clear supernatant background, it is recorded as a: - Answers 3+ reaction
The force of repulsion between the red cells in a physiologic saline solution is called: - Answers zeta
potential
While performing an antibody screen on a patient, you accidentally put four drops of patient plasma
into the tubes instead of two drops. This may result in false negative agglutination because of: - Answers
prozone
This test detects antibody that is already attached to red blood cells in vivo (in the body). - Answers
Direct Antiglobulin Test
Which test detects antibody in plasma? - Answers Indirect Antiglobulin Test
A mother who is group AB delivered a baby who is group A. The husband is Group O. Can the husband
be the father of the child? - Answers yes
A mother who is group A delivered a group AB baby. The husband is group AB. Is it possible for the
husband to be the father of the child? - Answers yes
Molecules that bind to an antigen to enhance phagocytosis are: - Answers Opsonins
Antibodies are produced by: - Answers B cells
A red cell antigen is: - Answers on the red cell membrane.
Which of the following describes the expression of most blood group inheritance? - Answers
Codominant
A gene that produces no detectable product is referred to as: - Answers an amorphic gene
A gene that is inherited in "trans" position to another gene is: - Answers on an opposite chromosome.
The CD designation used in Immunology refers to: - Answers Clusters of Differentiation
Which lymphocytes are considered T-helper cells? - Answers CD4 cells
"Humoral" immunity refers to: - Answers production of antibodies.
Lysis of RBCs in the circulation due to a transfusion reaction is caused by: - Answers activation of
complement by antigen-antibody complexes.
Recruitment of additional phagocytic cells to the site of antigen-antibody reaction is caused by: -
Answers Chemotaxins
Units of inheritance that produce antigens on Red Blood Cells are called: - Answers Genes
