and answers 2025
Organs .of .the .immune .system .- .ANS✓✓-- .bone .marrow
- .thymus
- .spleen
- .lymph .nodes, .tonsils, .peyer .patches
Bone .marrow .function .in .immune .system .- .ANS✓✓-Responsible .for .production
.of .immune .cells .and .the .maturation .of .B .cells
Thymus .function .in .immune .system .- .ANS✓✓-Provides .site .for .t-cell
.differentiation, .maturation .and .selection .(shrinks .as .we .grow)
Spleen .function .in .immune .system .- .ANS✓✓-contains .blood .filled .sinuses .that
.filter .antigens .and .cells .from .the .blood
- .red .pulp .(red .blood .cell .storage .and .turnover)
- .white .pulp .(where .immune .cell .interaction .occurs)
- .those .w/o .spleen .at .increased .risk .for .infection
Lymph .nodes .function .in .immune .system .- .ANS✓✓-antigens .interaction .with
.immune .cells
5 .types .of .immunity .- .ANS✓✓-1. .Natural .(Innate .resistance) .
2. .Active .Acquired
3. .Passive .Acquired
4. .Humoral .
5. .Cell-mediated
Normal .function .of .T-lymphocyte .- .ANS✓✓-- .develop .into .several .subsets .that
.identify .and .kill .target .cell .(t-cytoxic)
- .regulate .immune .response .by .helping .clonal .selection .process .(t-helper)
- .Suppress/limit .immune .response .(t-regulatory)
Normal .function .of .B-lymphocyte .- .ANS✓✓-develop .into .plasma .cells .that
.produce .antibody
Natural .Immunity .AKA .innate .resistance .immunity .- .ANS✓✓-
, Active .Acquired .Immunity .- .ANS✓✓-Produced .by .host .after .exposure .to .an
.antigen .(basis .of .vaccinations)
Passive .Acquired .Immunity .- .ANS✓✓-acquired .via .the .transfer .of .antibodies .or
.T-cells .to .recipient .(mother .to .fetus, .rabies)
Humoral .Immunity .- .ANS✓✓-conferred .by .B-cells; .provides .immunity .against
.some .viral .infections, .toxin .induced .diseases .and .diseases .caused .by
.pneumococci/meningicocci/hemophilus
Cell-mediated .Immunity .- .ANS✓✓-conferred .by .T-cells; .active .against .cells
.infected .with .IC .bacteria .or .virues; .responsible .for .organ .transplantation
.rejection
Antigen .(def) .- .ANS✓✓-describes .a .molecule .that .can .reach .with .binding .sites
.on .antibodies .or .antigen .receptors .on .B&T .cells
Self-antigen .(def) .- .ANS✓✓-part .of .individual's .makeup .that .fulfills .all .criteria
.EXCEPT .foreignness .and .does .not .normally .elicit .immune .response
Allergen .(def) .- .ANS✓✓-Antigen .that .induces .allergic .response
IgA .function .- .ANS✓✓-Main .immune .globulin .in .secretions .and .mucous
.membranes; .prevents .attachment .of .microorganisms .to .mucous .membranes
IgM .function .- .ANS✓✓-Main .immune .globulin .produced .EARLY .in .primary
.immune .response .(high .level .indicates .recent .infection)
IgG .function .- .ANS✓✓-Most .prominent; .binds .with .viruses, .bacteria .and .toxins;
.activates .complement .and .binds .to .macrophages; .primary .antibody .in
.secondary .immune .response; .levels .increase .in .response .to .repeated .exposure
.to .antigen; .only .one .that .crosses .placenta
IgE .function .- .ANS✓✓-Binds .to .mast .cells, .eosinophils, .basophils; .involved .in
.parasitic .infection .and .hypersensitivity .reactions
T-cytoxic .cells .(CD8) .AKA .Killer .T's .- .ANS✓✓-Kill .virus .infected .cells, .tumor
.cells .and .transplant .tissue .directly .through .the .release .of .cytotoxic .chemicals
.which .destroy .the .cell .membrane .or .induce .apoptosis
NK .Killer .cells .- .ANS✓✓-Similar .to .tc .cells, .kill .abnormal .cells .that .have
.suppressed .MHC .Class .I .expression; .lacks .CD8
T-Regulatory .cells .- .ANS✓✓-Slow .or .stop .the .immune .response .once .the
.invader .is .defeated.