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BIO484 EXAM 1 LATEST UPDATE 100% PASS

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BIO484 EXAM 1 LATEST UPDATE 100% PASS


Genetic analysis starts with.... - ANSWER isolation of mutants

How to geneticists analyze biological traits? (3) - ANSWER - detection of single-gene
inheritance pattern

- observing wild/mutant type phenotype in crosses

- genetic dissection

-Random mutagenesis

-irradiation & chemical mutagenesis

-spontaneous mutation

-identify phenotype

-identify gene

*** phenotype-driven approach!! - ANSWER forward genetics

-identify gene

-gene targeting

-transgenics, knock-outs/ins, gene trap

-identify phenotype

*** genotype-driven approach!! - ANSWER reverse genetics

first to elucidate the rules for single-gene inheritance pattern - ANSWER gregor mendel

Explain the process of genetic dissection. (3 steps) - ANSWER 1) cross a wild & mutant

2) cross their progeny

3) analyze ratio of mutant to wild types

Mendel used what to demonstrate his experiment? - ANSWER garden pea (pisum
sativum)

self-pollination produces... - ANSWER pure lines or true breeding

Mendel crossed "true breeding" plants by doing what? - ANSWER cross-pollination of
pea plants

Results of Mendel's experiment - ANSWER 3:1 ratio in F2 generation

, The 3:1 and 1:1 ratios also found for comparable crosses for .... - ANSWER all traits
Mendel studied

What is necessary for a character? - ANSWER hereditary factor

2 versions of traits - ANSWER dominant & recessive

genes come in 2 forms... - ANSWER dominant & recessive alleles

Each character is controlled by 2 alleles

• When both present, the.... - ANSWER dominant allele masks the expression of the
Recessive allele

fertilized egg with a pair of identical alleles - ANSWER homozygote

pair of different alleles - ANSWER heterozygote

Genetic makeup of an organism

• Allelic combinations: YY, Yy or yy - ANSWER genotype

• Physical expression of the genotype

• e.g., yellow or green peas - ANSWER phenotype

The alleles separate equally into eggs and sperm during... - ANSWER meiosis

Mendel's first law / law of equal separation - ANSWER

what is Mendel's first law of separation? - ANSWER At meiosis, alleles separate from
each other such that each gamete (egg or sperm) receives one copy from each allele
pair.



results of meiosis 2? - ANSWER 1/2 gametes with dominant allele (Y)

1/2 gametes with recessive allele (y)



distinguishing between homozygote dominant & heterozygote - ANSWER testcross



If YY (homozygous dominant), then.... - ANSWER 100% yellow



If Yy (heterozygous).... - ANSWER 50% yellow

50% green

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