NR 565 Pharmacology Week 1 Exam
Questions And Answers |Latest 2025 |
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Pharmacokinetics - Answer✔The study of drug absorption, distribution, metabolism, and
excretion in the body
"What the body does to the drug"
Factors that affect drug absorption (5) - Answer✔Rate of dissolution
Surface area
Blood flow
Lipid solubility
PH partitioning
Factors that affect drug distribution (4) - Answer✔Blood flow to tissues
Ability to exit vascular system
Blood-brain barrier
Protein-binding capacity
Pharmacodynamics - Answer✔The study of biochemical and physiologic effects of drugs on the
body and the molecular mechanisms by which those effects are produced
"What the body does to the drug"
Phamacodynamics: 3 mechanisms of action - Answer✔Receptor
Enzyme
Non-selective interactions (i.e. chemo)
Types of drug therapy (7) - Answer✔Acute
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Maintenance (HTN/bc)
Supplemental (insulin)
Palliative
Supportive (IV fluid)
Prophylactic
Empirical (broad-spectrum abx)
Idiosyncratic Effect - Answer✔Unexpected response to medication
Tolerance - Answer✔Declining response to a drug
Dependence - Answer✔Physiological/psychological need for a drug; needs drug for normal
function
Addiction - Answer✔Compulsive use of a drug despite negative/dangerous effects
Drug interactions: drug-drug - Answer✔When 2 drugs compete for metabolizing enzymes
Drug interactions: food-drug - Answer✔Grapefruit juice or leafy greens
Drug interactions: additive - Answer✔1+1 = 2; both provide intended effect
Drug interactions: antagonistic - Answer✔1+1 = <2; less than desired effect of one or both
drugs
Drug interactions: synergistic - Answer✔1+1 = >2; sum total effect is greater than if given alone
(i.e. lisinopril + HCTZ)
Drug interactions: incompatibility - Answer✔1+1 does not equal 2; two IV drugs given together
causing decomposition of one or both drugs
8 rights of medication administration - Answer✔Patient
Medication
Dose
Route
Time
Reason
Response
Documentation
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