Pharmacology Final Exam Questions
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While pharmacokinetics describes how the body deals with drugs,
_______ describes how drug molecules interact with their targets.
Ans: Pharmodynamics
Ionization of a drug depends upon the _______ of the solution and
the _______ of the drug.
Ans: pH; pKa
Which of the following about drug clearance by first-order kinetics
false?
Ans: Molecules of drug are cleared at a constant rate regardless of drug
concentration.
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After drug administration has occurred, the amount of drug in the
blood that is free to bind at specific target sites is/are referred to as
Ans: bioavailability
Which of the following about water soluble metabolites formed in
the liver is false?
Ans: They may return to the circulation and act on target tissues.
The absorption of a drug depends on all of the following except
Ans: body temperature
Because of _______, antidepressants known as monoamine oxidase
inhibitors can cause cardiac arrhythmias and high blood pressure in
patients that consume foods high in tyramine.
Ans: enzyme inhibition
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Repeated use of many psychoactive drugs can cause _______,
which can speed up the rate of biotransformation of these drugs as
well as others.
Ans: enzyme induction
While most _______ receptors are membrane-bound, many _______
receptors are intracellular.
Ans: neurotransmitter; hormone
Which of the following about depot binding is false?
Ans: It increases the concentration of drug at its site of action by releasing
large quantities at once.
Mitochondria are responsible for generating _______ for the cell in
the form of _______.
Ans: Energy; ATP
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Neuronal cell membranes are associated with all of the following
proteins except
Ans: microtubules
Clusters of cell bodies in the CNS are called _______ and their
associated bundles of axons are called _______.
Ans: nuclei; tracts
What kind of information is carried by the ventral roots of the spinal
cord?
Ans: Motor information to the muscles
Neurons responsible for converting environmental stimuli into neural
signals are known as
Ans: sensory neurons