NRNP 6675 Test with Right Answers
Most psychotropics have a medium range 1/2 life of approximately? - ✅✅
24 hours
What does "steady state" mean in relation to 1/2 life? - ✅✅ Steady state means
that you are eliminating the drug at the same overall rate that you are ingesting it
Lithium reaches its 'steady state' when? - ✅✅ 5 half lives
Fluoxetine has a half life of about? - ✅✅ 2 weeks 1/2 life
Take 2.5 months to achieve steady state
Most psychotropic medications operate in this fashion: - ✅✅ "when you double
the dose, the serum dose doubles."
*minus three sris and three anticonvulsants (Fluoxetine, fluvoxamine, paxil,
gabapentin, valproate and carbamazepine)
_________induces its own metabolism, hastening excretion and shortening its
half-life- ✅✅ Carbamazepine (Tegretol)
_____ has trouble getting a "serum" level because it binds to proteins that render it
therapeutically inactive. - ✅✅ Valproate Acid (Depakote)
, _______'s serum level is the opposite of Valproic Acid: it rises quickly at first and
then slows down. - ✅✅ Gabapentin
Gabapentin saturates the transporters that absorb it in the small intestine, causing
its levels to rise at a slow pace when the dosage goes above a certain saturation
point which is around 900 mg/day.
Due to Gabapentin's serum pattern for dosage:
@ 900 mg/day, how much is the patient absorbing? - ✅✅ @ 0900mg/day-60%
is absorbed
Due to Gabapentin's serum pattern for dosage:
@ 1200 mg/day, how much is the patient absorbing? - ✅✅ @ 1200 mg/day--50
% is absorbed.
Due to Gabapentin's serum pattern for dosage:
@ 3000 mg/day, how much is the patient absorbing? - ✅✅ @3000 mg/day--30%
of the gabapentin is absorbed.
Carbamazepine (Tegretol's) serum level drops after how long after stopping taking
it? - ✅✅ 1-2 months
For Valproate (Depakote), ___ dose changes can have big effects once the level is
beyond 50 mcg/ml? - ✅✅ small
Potency refers to a drug's? - ✅✅ Power per unit or the amount of
pharmacological activity per milligram.
The 1/2 life of lithium is about? - ✅✅ 24 hours
Most psychotropics have a medium range 1/2 life of approximately? - ✅✅
24 hours
What does "steady state" mean in relation to 1/2 life? - ✅✅ Steady state means
that you are eliminating the drug at the same overall rate that you are ingesting it
Lithium reaches its 'steady state' when? - ✅✅ 5 half lives
Fluoxetine has a half life of about? - ✅✅ 2 weeks 1/2 life
Take 2.5 months to achieve steady state
Most psychotropic medications operate in this fashion: - ✅✅ "when you double
the dose, the serum dose doubles."
*minus three sris and three anticonvulsants (Fluoxetine, fluvoxamine, paxil,
gabapentin, valproate and carbamazepine)
_________induces its own metabolism, hastening excretion and shortening its
half-life- ✅✅ Carbamazepine (Tegretol)
_____ has trouble getting a "serum" level because it binds to proteins that render it
therapeutically inactive. - ✅✅ Valproate Acid (Depakote)
, _______'s serum level is the opposite of Valproic Acid: it rises quickly at first and
then slows down. - ✅✅ Gabapentin
Gabapentin saturates the transporters that absorb it in the small intestine, causing
its levels to rise at a slow pace when the dosage goes above a certain saturation
point which is around 900 mg/day.
Due to Gabapentin's serum pattern for dosage:
@ 900 mg/day, how much is the patient absorbing? - ✅✅ @ 0900mg/day-60%
is absorbed
Due to Gabapentin's serum pattern for dosage:
@ 1200 mg/day, how much is the patient absorbing? - ✅✅ @ 1200 mg/day--50
% is absorbed.
Due to Gabapentin's serum pattern for dosage:
@ 3000 mg/day, how much is the patient absorbing? - ✅✅ @3000 mg/day--30%
of the gabapentin is absorbed.
Carbamazepine (Tegretol's) serum level drops after how long after stopping taking
it? - ✅✅ 1-2 months
For Valproate (Depakote), ___ dose changes can have big effects once the level is
beyond 50 mcg/ml? - ✅✅ small
Potency refers to a drug's? - ✅✅ Power per unit or the amount of
pharmacological activity per milligram.
The 1/2 life of lithium is about? - ✅✅ 24 hours
