(with 100% correct answers
(graded A+)
What is the function of the citric acid cycle? - answer Harvest high
energy electrons from carbon fuels
What product is found by the condensation of oxaloacetate and
acetyl CoA? - answer Citrate
What makes up citrate? - answer - Acetyl CoA
- Oxaloacetate
What is the intermediate between citrate and isocitrate? - answer
Cis-aconitate
Where is succinate dehydrogenase located? - answer Inner
membrane of mitochondria
What intermediate in the citric acid cycle is at both the beginning
and end of the cycle? - answer Oxaloacetate
What is the product of the complete oxidation of carbon in the citric
acid cycle? - answer Carbon Dioxide
What name is suggested for associated multienzyme complexes in
metabolism? - answer Metabolon
,What substance is a competitive inhibitor of succinate
dehydrogenase? - answer Melonate
What is the primary control point of the citric acid cycle? - answer
Isocitrate dehydrogenase
What is the name applied to metabolic reactions that replenish the
citric acid cycle intermediates that are depleted because they were
used for biosynthesis? - answer Anaplerotic reactions
What form are the carbons from carbohydrates in when they enter
the citric acid cycle? - answer Acetyl CoA
What is produced by a substrate-level phosphorylation in the citric
cycle? - answer GTP
What state is the free energy at the standard state for MDH in the
direction of the citric acid in? - answer Positive
What type of reactions fill up a cycle with outside carbon
compounds? - answer Anaplerotic reactions
What enzyme in the citric acid cycle is also an example of an iron-
sulfur protein? - answer Aconitase or succinate dehydrogenase
What organelles in plants and some bacteria where two-carbon
acetyl units are converted into four-carbon units (succinate) for
glucose synthesis. energy production. and biosynthesis? - answer
Glyoxysomes
Which intermediate in the oxidation of isocitrate is decarboxylated
to form alpha-ketoglutarate? - answer Oxalosuccinate
, What energy conditions (high or low) is the citric acid cycle inhibited
by? - answer High
What is the first intermediate to be oxidized in the citric acid cycle?
- answer Isocitrate
What cycle are organisms that can convert fat into sugar use? -
answer Glyoxylate cycle
What would a mutation in the active site of a succinyl CoA
synthetase where His is converted to a lysine would result in? -
answer The loss of a succinyl phosphate intermediate
What molecule initiates the citric acid cycle by reacting with
oxaloacetate? - answer Acetyl CoA
What enzyme in muscle is used to catalyze a substrate-level
phosphorylation? - answer Succinyl CoA synthetase
Where does the direct channeling of proteins from one enzyme to
the next happen? - answer Metabolon
What vitamins are precursors to coenzymes that are necessary for
the formation of succinyl CoA from alpha-ketoglutarate? - answer -
Thiamine
- Riboflavin
- Niacin
- Lipoic acid
- Pantothenic acid