,Chapterb 1:b Theb Roleb ofb theb Nurseb Practitionerb asb Prescriber
MultiplebChoice
Identifybthebchoicebthatbbestbcompletesbthebstatementborbanswersbthebquestion.
b
1. Nursebpractitionerb prescriptiveb authorityb isbregulatedb by:
A. ThebNationalb Councilb ofbStatebBoardsbofbNursing
B. ThebU.S.bDrugb Enforcementb Administration
C. ThebStatebBoardbofbNursingb forbeachbstate
D. ThebStatebBoardbofbPharmacy
b
2. Physicianb Assistantb (PA)bprescriptiveb authorityb isbregulatedb by:
A. ThebNationalb Councilb ofbStatebBoardsbofbNursing
B. ThebU.S.bDrugb Enforcementb Administration
C. ThebStatebBoardbofbNursing
D. ThebStatebBoardbofbMedicalb Examiners
b
3. Clinicalb judgmentb inb prescribingb includes:
A. Factoringb inb thebcostbtobthebpatientb ofbthebmedicationb prescribed
B. Alwaysb prescribingb thebnewestb medicationb availableb forbthebdiseasebprocess
C.b Handingb outbdrugbsamplesbbtobpoorbpatients
D.b Prescribingb allb genericb medicationsb tobcutbcosts
b
4. Criteriab forbchoosingb anbeffectiveb drugb forbabdisorderbinclude:
A. Askingb thebpatientb whatbdrugb theybthinkb wouldb workbbestbforbthem
B. Consultingb nationallyb recognizedb guidelinesb forbdiseasebmanagement
C. Prescribingb medicationsb thatbarebavailableb asbsamplesb beforebwritingb abprescription
D. Followingb U.S.bDrugb Enforcementb Administrationb (DEA)bguidelinesb for
prescribing
b
5. Nursebpractitionerb practiceb maybthriveb underbhealth-careb reformb duebto:
A. Thebdemonstratedb abilityb ofbnurseb practitionersb tobcontrolb costsbandbimproveb patientbo
utcomes
B. Thebfactbthatbnurseb practitionersb willb bebablebtobpracticebindependently
C. Thebfactbthatbnurseb practitionersb willb haveb fullb reimbursementb underbhealth-care
reform
D.b Thebabilityb tobshiftb accountabilityb forbMedicaidb tobthebstateblevel
,Chapterb 1:b Theb Rolebofb theb Nurseb Practitionerb asb PrescriberbA
nswerbSection
MULTIPLEb CHOICE
1. ANS:b C PTS:bb 1
2. ANS:b D PTS:bb 1
3. ANS:b A PTS:bb 1
4. ANS:b B PTS:bb 1
5. ANS:b A PTS:bb 1
Chapterb 2:b Reviewb ofb Basicb Principlesb ofb Pharmacology
MultiplebChoice
Identifybthebchoicebthatbbestbcompletesbthebstatementborbanswersbthebquestion.
b
1. Abpatient’sb nutritionalb intakeb andblabbworkbreflectsb hypoalbuminemia.b Thisb isbcriticalb tobp
rescribingb because:
A. Distributionb ofbdrugsbtobtargetbtissueb maybbebaffected
B. Thebsolubilityb ofbthebdrugb willb notbmatchb thebsitebofbabsorption
C. Therebwillb beblessbfreebdrugb availableb tobgenerateb anbeffect
D. Drugsb boundbtobalbuminb arebreadilyb excretedbbybthebkidney
b
2. Drugsb thatbhavebabsignificantb first-passb effect:
A. Mustbbebgivenb bybthebenteralb (oral)broutebonly
B. Bypassbthebhepaticb circulation
C. Arebrapidlyb metabolizedb bybthebliverb andbmaybhaveblittleb ifbanyb desiredbaction
D. Arebconvertedb bybthebliverb tobmorebactiveb andbfat-solubleb forms
b
3. Thebroutebofbexcretionb ofbabvolatileb drugbwillb likelyb be:
A. Thebkidneys
B. Theblungs
C. Thebbileb andbfeces
D. Thebskin
b 4. Medroxyprogesteroneb (DepobProvera)bisbprescribedb IMbtobcreatebabstoragebreservoirb ofbthe
drug.bStoragebreservoirs:
A. Assurebthatbthebdrugbwillb reachbitsbintendedb targetb tissue
B. Arebthebreasonbforbgivingb loadingb doses
C. Increasebtheblengthb ofbtimeb abdrugbisbavailableb andbactive
D. Arebmostbcommonb inb collagenb tissues
b
5. ThebNPbchoosesbtobgiveb cephalexinb everyb 8bhoursb basedbonbknowledgeb ofbthebdrug’s:
A. Propensityb tobgobtobthebtargetbreceptor
B. Biologicalb half-life
C. Pharmacodynamics
D. Safetyb andbsidebeffects
b
6. Azithromycinb dosingb requiresb thebfirstb day’sbdosebbebtwicebthosebofbthebotherb4bdaysbofbthebp
rescription.bThisb isbconsideredb abloadingb dose.bAbloadingb dose:
A. Rapidlyb achievesb drugblevelsb inb thebtherapeuticb range
B. Requiresb fourb tobfiveb half-livesb tobattain
, C.b Isbinfluencedb bybrenalb function
D.b Isbdirectlyb relatedb tobthebdrugbcirculatingb tobthebtargetbtissues
b
7.b Thebpointb inbtimeb onbthebdrugbbconcentrationb curvebthatbindicatesb thebfirstb signb ofbabtherapeut
icbeffectb isbthe:
A. Minimumb adversebeffectb level
B. Peakbofbaction
C. Onsetbofbaction
D. Therapeuticb range
b 8.b Phenytoinb requiresb abtroughb levelb bebdrawn.bPeakbandbtroughb levelsb arebdone:
A. Whenbthebdrugbhasbabwidebtherapeuticb range
B. Whenbthebdrugbwillb bebadministeredb forbabshortbtimeb only
C. Whenbtherebisbabhighb correlationb betweenbthebdosebandbsaturationb ofbreceptorbsites
D. Tobdetermineb ifb abdrugbisbinbthebtherapeuticb range
b
9.bAblaboratorybresultbindicatesbthebpeakblevelbforbabdrugbisbabovebthebminimumbtoxicbc
oncentration.b Thisb meansbthatbthe:
A. Concentrationb willb producebtherapeuticb effects
B. Concentrationb willb producebanbadversebresponse
C. Timeb betweenbdosesbmustb bebshortened
D. Durationb ofbactionb ofbthebdrugb isbtooblong
b bb 10.b Drugsb thatbarebreceptorbagonistsb maybdemonstrateb whatb property?
A. Irreversibleb bindingb tobthebdrugbreceptorbsite
B. Up-regulationb withb chronicb use
C. Desensitizationb orbdown-regulationb withb continuousb use
D. Inverseb relationshipb betweenbdrugbconcentrationb andbdrugbaction
b bb 11.b Drugsb thatbarebreceptorbantagonists,b suchbasbbetabblockers,b maybcause:
A. Down-regulationb ofbthebdrugb receptor
B. Anbexaggeratedb responsebifb abruptlyb discontinued
C. Partialb blockadebofbthebeffectsb ofbagonistb drugs
D. Anbexaggeratedb responsebtobcompetitiveb drugbagonists
b bb 12.b Factorsbthatbaffectb gastricb drugb absorptionb include:
A. Liverb enzymeb activity
B. Protein-bindingb propertiesb ofbthebdrugb molecule
C. Lipidb solubilitybbofbthebdrug
D. Abilityb tobchewbandbswallow
b bb 13.bbDrugsb administeredb viabintravenousb (IV)broute:
A. Needbtobbeblipidb solubleb inborderbtobbebeasilyb absorbed
B. Beginb distributionb intob thebbodybimmediately
C. Arebeasilyb absorbedbifb theybarebnonionized
D. Maybusebpinocytosisb tobbebabsorbed
b
bb 14.bbWhenbabmedicationb isbaddedbtobabregimenb forbabsynergisticb effect,b thebcombinedb effectb of
thebdrugsb is:
b
A. Thebsumb ofbthebeffectsb ofbeachbdrugbindividually
B. Greaterbthanb thebsumb ofbthebeffectsb ofbeachbdrugbindividually
C. Lessbthanb thebeffectb ofbeachbdrugbindividually
D. Notbpredictable,b asbitbvariesb withb eachbindividual
MultiplebChoice
Identifybthebchoicebthatbbestbcompletesbthebstatementborbanswersbthebquestion.
b
1. Nursebpractitionerb prescriptiveb authorityb isbregulatedb by:
A. ThebNationalb Councilb ofbStatebBoardsbofbNursing
B. ThebU.S.bDrugb Enforcementb Administration
C. ThebStatebBoardbofbNursingb forbeachbstate
D. ThebStatebBoardbofbPharmacy
b
2. Physicianb Assistantb (PA)bprescriptiveb authorityb isbregulatedb by:
A. ThebNationalb Councilb ofbStatebBoardsbofbNursing
B. ThebU.S.bDrugb Enforcementb Administration
C. ThebStatebBoardbofbNursing
D. ThebStatebBoardbofbMedicalb Examiners
b
3. Clinicalb judgmentb inb prescribingb includes:
A. Factoringb inb thebcostbtobthebpatientb ofbthebmedicationb prescribed
B. Alwaysb prescribingb thebnewestb medicationb availableb forbthebdiseasebprocess
C.b Handingb outbdrugbsamplesbbtobpoorbpatients
D.b Prescribingb allb genericb medicationsb tobcutbcosts
b
4. Criteriab forbchoosingb anbeffectiveb drugb forbabdisorderbinclude:
A. Askingb thebpatientb whatbdrugb theybthinkb wouldb workbbestbforbthem
B. Consultingb nationallyb recognizedb guidelinesb forbdiseasebmanagement
C. Prescribingb medicationsb thatbarebavailableb asbsamplesb beforebwritingb abprescription
D. Followingb U.S.bDrugb Enforcementb Administrationb (DEA)bguidelinesb for
prescribing
b
5. Nursebpractitionerb practiceb maybthriveb underbhealth-careb reformb duebto:
A. Thebdemonstratedb abilityb ofbnurseb practitionersb tobcontrolb costsbandbimproveb patientbo
utcomes
B. Thebfactbthatbnurseb practitionersb willb bebablebtobpracticebindependently
C. Thebfactbthatbnurseb practitionersb willb haveb fullb reimbursementb underbhealth-care
reform
D.b Thebabilityb tobshiftb accountabilityb forbMedicaidb tobthebstateblevel
,Chapterb 1:b Theb Rolebofb theb Nurseb Practitionerb asb PrescriberbA
nswerbSection
MULTIPLEb CHOICE
1. ANS:b C PTS:bb 1
2. ANS:b D PTS:bb 1
3. ANS:b A PTS:bb 1
4. ANS:b B PTS:bb 1
5. ANS:b A PTS:bb 1
Chapterb 2:b Reviewb ofb Basicb Principlesb ofb Pharmacology
MultiplebChoice
Identifybthebchoicebthatbbestbcompletesbthebstatementborbanswersbthebquestion.
b
1. Abpatient’sb nutritionalb intakeb andblabbworkbreflectsb hypoalbuminemia.b Thisb isbcriticalb tobp
rescribingb because:
A. Distributionb ofbdrugsbtobtargetbtissueb maybbebaffected
B. Thebsolubilityb ofbthebdrugb willb notbmatchb thebsitebofbabsorption
C. Therebwillb beblessbfreebdrugb availableb tobgenerateb anbeffect
D. Drugsb boundbtobalbuminb arebreadilyb excretedbbybthebkidney
b
2. Drugsb thatbhavebabsignificantb first-passb effect:
A. Mustbbebgivenb bybthebenteralb (oral)broutebonly
B. Bypassbthebhepaticb circulation
C. Arebrapidlyb metabolizedb bybthebliverb andbmaybhaveblittleb ifbanyb desiredbaction
D. Arebconvertedb bybthebliverb tobmorebactiveb andbfat-solubleb forms
b
3. Thebroutebofbexcretionb ofbabvolatileb drugbwillb likelyb be:
A. Thebkidneys
B. Theblungs
C. Thebbileb andbfeces
D. Thebskin
b 4. Medroxyprogesteroneb (DepobProvera)bisbprescribedb IMbtobcreatebabstoragebreservoirb ofbthe
drug.bStoragebreservoirs:
A. Assurebthatbthebdrugbwillb reachbitsbintendedb targetb tissue
B. Arebthebreasonbforbgivingb loadingb doses
C. Increasebtheblengthb ofbtimeb abdrugbisbavailableb andbactive
D. Arebmostbcommonb inb collagenb tissues
b
5. ThebNPbchoosesbtobgiveb cephalexinb everyb 8bhoursb basedbonbknowledgeb ofbthebdrug’s:
A. Propensityb tobgobtobthebtargetbreceptor
B. Biologicalb half-life
C. Pharmacodynamics
D. Safetyb andbsidebeffects
b
6. Azithromycinb dosingb requiresb thebfirstb day’sbdosebbebtwicebthosebofbthebotherb4bdaysbofbthebp
rescription.bThisb isbconsideredb abloadingb dose.bAbloadingb dose:
A. Rapidlyb achievesb drugblevelsb inb thebtherapeuticb range
B. Requiresb fourb tobfiveb half-livesb tobattain
, C.b Isbinfluencedb bybrenalb function
D.b Isbdirectlyb relatedb tobthebdrugbcirculatingb tobthebtargetbtissues
b
7.b Thebpointb inbtimeb onbthebdrugbbconcentrationb curvebthatbindicatesb thebfirstb signb ofbabtherapeut
icbeffectb isbthe:
A. Minimumb adversebeffectb level
B. Peakbofbaction
C. Onsetbofbaction
D. Therapeuticb range
b 8.b Phenytoinb requiresb abtroughb levelb bebdrawn.bPeakbandbtroughb levelsb arebdone:
A. Whenbthebdrugbhasbabwidebtherapeuticb range
B. Whenbthebdrugbwillb bebadministeredb forbabshortbtimeb only
C. Whenbtherebisbabhighb correlationb betweenbthebdosebandbsaturationb ofbreceptorbsites
D. Tobdetermineb ifb abdrugbisbinbthebtherapeuticb range
b
9.bAblaboratorybresultbindicatesbthebpeakblevelbforbabdrugbisbabovebthebminimumbtoxicbc
oncentration.b Thisb meansbthatbthe:
A. Concentrationb willb producebtherapeuticb effects
B. Concentrationb willb producebanbadversebresponse
C. Timeb betweenbdosesbmustb bebshortened
D. Durationb ofbactionb ofbthebdrugb isbtooblong
b bb 10.b Drugsb thatbarebreceptorbagonistsb maybdemonstrateb whatb property?
A. Irreversibleb bindingb tobthebdrugbreceptorbsite
B. Up-regulationb withb chronicb use
C. Desensitizationb orbdown-regulationb withb continuousb use
D. Inverseb relationshipb betweenbdrugbconcentrationb andbdrugbaction
b bb 11.b Drugsb thatbarebreceptorbantagonists,b suchbasbbetabblockers,b maybcause:
A. Down-regulationb ofbthebdrugb receptor
B. Anbexaggeratedb responsebifb abruptlyb discontinued
C. Partialb blockadebofbthebeffectsb ofbagonistb drugs
D. Anbexaggeratedb responsebtobcompetitiveb drugbagonists
b bb 12.b Factorsbthatbaffectb gastricb drugb absorptionb include:
A. Liverb enzymeb activity
B. Protein-bindingb propertiesb ofbthebdrugb molecule
C. Lipidb solubilitybbofbthebdrug
D. Abilityb tobchewbandbswallow
b bb 13.bbDrugsb administeredb viabintravenousb (IV)broute:
A. Needbtobbeblipidb solubleb inborderbtobbebeasilyb absorbed
B. Beginb distributionb intob thebbodybimmediately
C. Arebeasilyb absorbedbifb theybarebnonionized
D. Maybusebpinocytosisb tobbebabsorbed
b
bb 14.bbWhenbabmedicationb isbaddedbtobabregimenb forbabsynergisticb effect,b thebcombinedb effectb of
thebdrugsb is:
b
A. Thebsumb ofbthebeffectsb ofbeachbdrugbindividually
B. Greaterbthanb thebsumb ofbthebeffectsb ofbeachbdrugbindividually
C. Lessbthanb thebeffectb ofbeachbdrugbindividually
D. Notbpredictable,b asbitbvariesb withb eachbindividual