Chapter 22 Microbial Diseases of the Nervous System
22.1 Multiple-Choice Questions
1) All of the following are true regarding African trypanosomiasis EXCEPT A) it is also
known as "sleeping sickness."
B) all subspecies of Trypanosoma brucei have multiple hosts. C) it is transmitted by the
tsetse fly.
D) death ultimately occurs without proper treatment.
E) Trypanosoma brucei gambiense is the more common cause of disease. Answer: B
Section: 22.5
Bloom's Taxonomy: Remembering
ASMcue Outcome: 5.4
Learning Outcome: 22.13
2) Bacterial encephalitis and meningitis are difficult to treat because
A) no medications exist for treatment of these infections. B) antibiotics damage nervous
tissue.
C) many antibiotics cannot penetrate the blood-brain barrier. D) the infections move along
peripheral nerves.
E) it is very difficult to determine the causative microbe. Answer: C
Section: 22.2
Bloom's Taxonomy: Remembering
ASMcue Outcome: 3.4
Learning Outcome: 22.4
3) All of the following organisms cause meningitis EXCEPT A) Neisseria meningitidis.
B) Haemophilus influenzae. C) Cryptococcus neoformans. D) Streptococcus pneumoniae. E)
Mycobacterium leprae. Answer: E
Section: 22.1
Bloom's Taxonomy: Remembering
ASMcue Outcome: 5.4
Learning Outcome: 22.2
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4) Which of the following statements about Neisseria meningitis is FALSE? A) A healthy
carrier state can exist.
B) It is encapsulated.
C) It is typically transmitted by droplet aerosols or direct contact with secretions. D) Its most
distinguishing feature is a unique rash.
E) It is a gram-positive anaerobe. Answer: E
Section: 22.2
Bloom's Taxonomy: Understanding
ASMcue Outcome: 5.4
Learning Outcome: 22.3
Global Outcome: 2
5) Which of the following pairs is mismatched?
A) Neisseria meningitidis – produces deadly endotoxins B) Haemophilus influenzae –
virulence due to capsule C) Mycobacterium leprae – grows in armadillos
D) Cryptococcus neoformans – acid-fast rod
E) Naegleria fowleri – causes amoebic meningoencephalitis
Answer: D Section: 22.4
Bloom's Taxonomy: Understanding
Learning Outcome: 22.12
Global Outcome: 2
6) All of the following organisms are correctly matched to the recommended treatment
EXCEPT A) Neisseria meningitidis – cephalosporins.
B) Haemophilus influenzae – cephalosporins.
C) Cryptococcus neoformans – amphotericin B. D) Mycobacterium leprae – dapsone.
E) poliovirus – amphotericin B. Answer: E
Section: 22.3
Bloom's Taxonomy: Understanding
ASMcue Outcome: 3.4
Learning Outcome: 22.8
Global Outcome: 2
7) Which of the following statements about leprosy is FALSE? A) It is rarely fatal.
B) Patients with leprosy must be isolated. C) It is transmitted by direct contact.
D) Diagnosis is based on skin biopsy.
E) The etiologic agent is acid-fast. Answer: B
, lO M oA 4 4 70 89
Section: 22.2
Bloom's Taxonomy: Analyzing
ASMcue Outcome: 5.4
Learning Outcome: 22.7
Global Outcome: 2
8) All of the following organisms are transmitted via the respiratory route EXCEPT A)
Neisseria meningitidis.
B) Haemophilus influenzae. C) Listeria monocytogenes.
D) Cryptococcus neoformans.
E) None of the answers is correct; all of these organisms are transmitted by the respiratory
route.
Answer: C Section: 22.2
Bloom's Taxonomy: Remembering
ASMcue Outcome: 5.4
Learning Outcome: 22.3
9) Which of the following statements about rabies is FALSE? A) It is caused by Lyssavirus.
B) Hydrophobia is associated with the disease.
C) Most infections in the U.S. are the result of bites from infected dogs. D) Diagnosis is
based on immunofluorescent techniques.
E) Average incubation period is 30 to 50 days after initial infection. Answer: C
Section: 22.3
Bloom's Taxonomy: Remembering
ASMcue Outcome: 5.4
Learning Outcome: 22.10
10) The symptoms of tetanus are due to
A) endospore formation. B) systemic infection.
C) sustained relaxation of muscles. D) tetanospasmin.
E) inflammation. Answer: D Section: 22.2
Bloom's Taxonomy: Remembering
ASMcue Outcome: 5.4
Learning Outcome: 22.5
11) All of the following diseases are caused by arbovirus EXCEPT A) St. Louis encephalitis.
B) eastern equine encephalitis.
22.1 Multiple-Choice Questions
1) All of the following are true regarding African trypanosomiasis EXCEPT A) it is also
known as "sleeping sickness."
B) all subspecies of Trypanosoma brucei have multiple hosts. C) it is transmitted by the
tsetse fly.
D) death ultimately occurs without proper treatment.
E) Trypanosoma brucei gambiense is the more common cause of disease. Answer: B
Section: 22.5
Bloom's Taxonomy: Remembering
ASMcue Outcome: 5.4
Learning Outcome: 22.13
2) Bacterial encephalitis and meningitis are difficult to treat because
A) no medications exist for treatment of these infections. B) antibiotics damage nervous
tissue.
C) many antibiotics cannot penetrate the blood-brain barrier. D) the infections move along
peripheral nerves.
E) it is very difficult to determine the causative microbe. Answer: C
Section: 22.2
Bloom's Taxonomy: Remembering
ASMcue Outcome: 3.4
Learning Outcome: 22.4
3) All of the following organisms cause meningitis EXCEPT A) Neisseria meningitidis.
B) Haemophilus influenzae. C) Cryptococcus neoformans. D) Streptococcus pneumoniae. E)
Mycobacterium leprae. Answer: E
Section: 22.1
Bloom's Taxonomy: Remembering
ASMcue Outcome: 5.4
Learning Outcome: 22.2
, lO M oA 4 4 70 89
4) Which of the following statements about Neisseria meningitis is FALSE? A) A healthy
carrier state can exist.
B) It is encapsulated.
C) It is typically transmitted by droplet aerosols or direct contact with secretions. D) Its most
distinguishing feature is a unique rash.
E) It is a gram-positive anaerobe. Answer: E
Section: 22.2
Bloom's Taxonomy: Understanding
ASMcue Outcome: 5.4
Learning Outcome: 22.3
Global Outcome: 2
5) Which of the following pairs is mismatched?
A) Neisseria meningitidis – produces deadly endotoxins B) Haemophilus influenzae –
virulence due to capsule C) Mycobacterium leprae – grows in armadillos
D) Cryptococcus neoformans – acid-fast rod
E) Naegleria fowleri – causes amoebic meningoencephalitis
Answer: D Section: 22.4
Bloom's Taxonomy: Understanding
Learning Outcome: 22.12
Global Outcome: 2
6) All of the following organisms are correctly matched to the recommended treatment
EXCEPT A) Neisseria meningitidis – cephalosporins.
B) Haemophilus influenzae – cephalosporins.
C) Cryptococcus neoformans – amphotericin B. D) Mycobacterium leprae – dapsone.
E) poliovirus – amphotericin B. Answer: E
Section: 22.3
Bloom's Taxonomy: Understanding
ASMcue Outcome: 3.4
Learning Outcome: 22.8
Global Outcome: 2
7) Which of the following statements about leprosy is FALSE? A) It is rarely fatal.
B) Patients with leprosy must be isolated. C) It is transmitted by direct contact.
D) Diagnosis is based on skin biopsy.
E) The etiologic agent is acid-fast. Answer: B
, lO M oA 4 4 70 89
Section: 22.2
Bloom's Taxonomy: Analyzing
ASMcue Outcome: 5.4
Learning Outcome: 22.7
Global Outcome: 2
8) All of the following organisms are transmitted via the respiratory route EXCEPT A)
Neisseria meningitidis.
B) Haemophilus influenzae. C) Listeria monocytogenes.
D) Cryptococcus neoformans.
E) None of the answers is correct; all of these organisms are transmitted by the respiratory
route.
Answer: C Section: 22.2
Bloom's Taxonomy: Remembering
ASMcue Outcome: 5.4
Learning Outcome: 22.3
9) Which of the following statements about rabies is FALSE? A) It is caused by Lyssavirus.
B) Hydrophobia is associated with the disease.
C) Most infections in the U.S. are the result of bites from infected dogs. D) Diagnosis is
based on immunofluorescent techniques.
E) Average incubation period is 30 to 50 days after initial infection. Answer: C
Section: 22.3
Bloom's Taxonomy: Remembering
ASMcue Outcome: 5.4
Learning Outcome: 22.10
10) The symptoms of tetanus are due to
A) endospore formation. B) systemic infection.
C) sustained relaxation of muscles. D) tetanospasmin.
E) inflammation. Answer: D Section: 22.2
Bloom's Taxonomy: Remembering
ASMcue Outcome: 5.4
Learning Outcome: 22.5
11) All of the following diseases are caused by arbovirus EXCEPT A) St. Louis encephalitis.
B) eastern equine encephalitis.
