ADVANCED PHARMACOLOGY FINAL EXAM REVIEW QUESTIONS
WITH COMPLETE SOLUTION QUESTIONS WITH CORRECT
ANSWERS.
Why are nitrate-free periods every 24 hours necessary for the patient on nitroglycerin th
erapy?
~ Correct answer ~ To inhibit the development of,tolerance
What does a,low level,of thyroid-stimulating,hormone indicate?
~ Correct answer ~ Hyperthroidism
What would be the best option to treat a newly diagnosed patient with,a, low,TSH level
with?
~ Correct answer ~ Propanolol (Inderal)
Spironoaldactone (Aldactone) has what,mechanism,of,action (MOA)?
~Correct answer ~ Aldosterone antagonist
Heparin exerts its therapeutic action by what?
~ Correct answer ~ Upregu lating,the activity,of one of the body's natural anticoagulant
molecules, antithrombin III
What physiologic action happens when the offending drug,is administer ed during an
anaphylactic reaction.
~ Correct answer ~ Mast cells liberate large doses of histamine.
What are two systemic psoriasis medications?
~ Correct answer ~ Photo- therapy and topical corticosteroids
, What is the first choice of drug,therapy for the,majority of patients with uncomplicated
stage I hypertension?
~ Correct answer ~ Thiazide diureti cs
What is the effect of cardiac glycosides?
~ Correct answer ~ Digitalis glyco sides have,a negative chronotropic effect on the
cardiac muscle cells.
Amenorrhea is the most common side effect of which birth,control medic ation?
~ Correct answer ~ Medroxyprogesterone (Depo-Provera)
What is an,anti-
hypertensive agent which competes with epinephrine for available beta
-receptor sites?
~ Correct answer ~ Atenolol (Tenormin)
What type of action,does nitrates have on the body?
~ Correct answer ~ Re duction,in,systemic venous tone.
What is the recommended level of,low-
density,lipoprotein cholesterol (LDL) for,patients with,known coronary artery,disease?
~ Correct answer ~ 100mg/dl or less.
What is the MOA,of group IV anti-
dysrhythmia drugs?
~ Correct answer ~ Depressing,phase 4,depolarizatio n,and lengthening phases 1 and 2
repolarization.
Which,drug therapy should be used,to lower the serum concentration of thyroid
hormones and re-
establish,eumetabolic state in,a patient with Graves' disease?
~ Correct a nswer ~ Anti-thyroid drugs.
WITH COMPLETE SOLUTION QUESTIONS WITH CORRECT
ANSWERS.
Why are nitrate-free periods every 24 hours necessary for the patient on nitroglycerin th
erapy?
~ Correct answer ~ To inhibit the development of,tolerance
What does a,low level,of thyroid-stimulating,hormone indicate?
~ Correct answer ~ Hyperthroidism
What would be the best option to treat a newly diagnosed patient with,a, low,TSH level
with?
~ Correct answer ~ Propanolol (Inderal)
Spironoaldactone (Aldactone) has what,mechanism,of,action (MOA)?
~Correct answer ~ Aldosterone antagonist
Heparin exerts its therapeutic action by what?
~ Correct answer ~ Upregu lating,the activity,of one of the body's natural anticoagulant
molecules, antithrombin III
What physiologic action happens when the offending drug,is administer ed during an
anaphylactic reaction.
~ Correct answer ~ Mast cells liberate large doses of histamine.
What are two systemic psoriasis medications?
~ Correct answer ~ Photo- therapy and topical corticosteroids
, What is the first choice of drug,therapy for the,majority of patients with uncomplicated
stage I hypertension?
~ Correct answer ~ Thiazide diureti cs
What is the effect of cardiac glycosides?
~ Correct answer ~ Digitalis glyco sides have,a negative chronotropic effect on the
cardiac muscle cells.
Amenorrhea is the most common side effect of which birth,control medic ation?
~ Correct answer ~ Medroxyprogesterone (Depo-Provera)
What is an,anti-
hypertensive agent which competes with epinephrine for available beta
-receptor sites?
~ Correct answer ~ Atenolol (Tenormin)
What type of action,does nitrates have on the body?
~ Correct answer ~ Re duction,in,systemic venous tone.
What is the recommended level of,low-
density,lipoprotein cholesterol (LDL) for,patients with,known coronary artery,disease?
~ Correct answer ~ 100mg/dl or less.
What is the MOA,of group IV anti-
dysrhythmia drugs?
~ Correct answer ~ Depressing,phase 4,depolarizatio n,and lengthening phases 1 and 2
repolarization.
Which,drug therapy should be used,to lower the serum concentration of thyroid
hormones and re-
establish,eumetabolic state in,a patient with Graves' disease?
~ Correct a nswer ~ Anti-thyroid drugs.
