Pharmacokinetics I - Practice Test Questions
With Answers
What are the characteristics of SoLute Carrier (SLC) transporters? Carriers for small
molecules across the membrane, Expressed in many different epithelial membranes, Include over
300 members organized into 52 families
Why does intravenous drug administration bypass drug absorption and metabolism? To
deliver the drug directly into the bloodstream
Why do carrier proteins transport drugs based on their chemical characteristics? To
facilitate the transport of drugs across cell membranes
What is the role of P-glycoprotein (P-gp)? Active efflux pump for anticancer drugs,
Member of ATP-binding cassette (ABC) transporters
What are the major organs where P-gp is abundant? Intestine, Liver, Kidney, Placenta,
Blood-brain barrier (BBB), Pancreas, Colon, Testis
What are the major organs where BCRP is found? Intestine, Liver, Kidney, Placenta,
BBB, Bronchi
With Answers
What are the characteristics of SoLute Carrier (SLC) transporters? Carriers for small
molecules across the membrane, Expressed in many different epithelial membranes, Include over
300 members organized into 52 families
Why does intravenous drug administration bypass drug absorption and metabolism? To
deliver the drug directly into the bloodstream
Why do carrier proteins transport drugs based on their chemical characteristics? To
facilitate the transport of drugs across cell membranes
What is the role of P-glycoprotein (P-gp)? Active efflux pump for anticancer drugs,
Member of ATP-binding cassette (ABC) transporters
What are the major organs where P-gp is abundant? Intestine, Liver, Kidney, Placenta,
Blood-brain barrier (BBB), Pancreas, Colon, Testis
What are the major organs where BCRP is found? Intestine, Liver, Kidney, Placenta,
BBB, Bronchi
