LIFE AT q
THE MOLECULAR
q q
LEVEL
Voet Voet Pratt
F O U R T H E D I T I O N
Akif Uzman
q Jerry Johnson Joseph Eichberg
q q
William WidgerDonald Voet
q q q
Judith G. Voet
q Charlotte W. Pratt
q q q
,Thisqpageqisqintentionallyqleftqblank
,STUDENT COMPANION TO ACCOMPANY q q q
FUNDAMENTALS OF q
BIOCHEMISTRY
LIFE AT THE MOLECULAR LEVEL
q q q q
Fourth Edition q
Akif Uzman
q
University of Houston q q
Jerry Johnson
q
University of Houston q q
Joseph Eichberg q
University of Houston q q
William Widger q
University of Houston q q
Donald Voet q
University of Pennsylvania q q
Judith G. Voet q q
Swarthmore College q
Charlotte W. Pratt q q
Seattle, Washington q
JOHNqWILEYq&qSONS,qINC
, CoverqDesignerqMadelynqLesureqCo
verqIllustrationqNormqChristiansenqC
overqPhotos
(VitruvianqMan):q©qOdysseus/Alamyqandq©qDennisqHallinan/Alamy
Molecularqstructuresqclockwiseqfromqtop:qbasedqonqX-
rayqstructuresqthatqwereqrespectivelyqdeterminedqbyqRichardqDickersonqandqHoraceqDrew,qCaltech;qGer
ardqBunick,qUniversityqofqTennessee;qThomasqSteitz,qYaleqUniversity;qAlfonsoqMondragón,qNorthwest
ernqUniversity;qVenkiqRamakrishnan,qMRCqLaboratoryqofqMolecularqBiology,qCambridge,qU.K.;qAndr
ewqLeslieqandqJohnqWalker,qMRCqLaboratoryqofqMolecularqBiology,qCambridge,qU.K.
Foundedqinq1807,qJohnqWileyq&qSons,qInc.qhasqbeenqaqvaluedqsourceqofqknowledgeqandqunderstandingqfor
qmoreqthanq200qyears,qhelpingqpeopleqaroundqtheqworldqmeetqtheirqneedsqandqfulfillqtheirqaspirations.qOurq
companyqisqbuiltqonqaqfoundationqofqprinciplesqthatqincludeqresponsibilityqtoqtheqcommunitiesqweqserveqan
dqwhereqweqliveqandqwork.qInq2008,qweqlaunchedqaqCorporateqCitizenshipqInitiative,qaqglobalqeffortqtoqaddr
essqtheqenvironmental,qsocial,qeconomic,qandqethicalqchallengesqweqfaceqinqourqbusiness.qAmongqtheqissue
sqweqareqaddressingqareqcarbonqimpact,qpaperqspecificationsqandqprocurement,qethicalqconductqwithinqourq
businessqandqamongqourqvendors,qandqcommunityqandqcharitableqsupport.qForqmoreqinformation,qpleaseqv
isitqourqwebsite:qwww.wiley.com/go/citizenship.
Copyrightq©q2012 JohnqWileyq&qSons,qInc.
Allqrightsqreserved.qNoqpartqofqthisqpublicationqmayqbeqreproduced,qstoredqinqaqretrievalqsystemqorqtrans
mittedqinqanyqformqorqbyqanyqmeans,qelectronic,qmechanical,qphotocopying,qrecording,qscanningqorqother
wise,qexceptqasqpermittedqunderqSectionsq107qorq108qofqtheq1976qUnitedqStatesqCopyrightqAct,qwithoutqe
itherqtheqpriorqwrittenqpermissionqofqtheqPublisher,qorqauthorizationqthroughqpaymentqofqtheqappropriateq
per-
copyqfeeqtoqtheqCopyrightqClearanceqCenter,qInc.,q222qRosewoodqDrive,qDanvers,qMAq01923,qwebsiteqw
ww.copyright.com.qRequestsqtoqtheqPublisherqforqpermissionqshouldqbeqaddressedqtoqtheqPermissionsqDe
partment,qJohnqWileyq&qSons,qInc.q111qRiverqStreet,qHoboken,qNJq07030-5774,q(201)q748-
6011,qfaxq(201)q748-6008,qwebsiteqhttp://www.wiley.com/go/permissions.
Toqorderqbooksqorqforqcustomerqservice,qpleaseqcallq1-800-CALLqWILEYq(225-5945).
StudentqCompanionq(paperback) ISBN-13q 978-1-1182-1827-3
PrintedqinqtheqUnitedqStatesqofqAmeric
aq10q 9q8q7q 6q5q4q 3q2q1
THE MOLECULAR
q q
LEVEL
Voet Voet Pratt
F O U R T H E D I T I O N
Akif Uzman
q Jerry Johnson Joseph Eichberg
q q
William WidgerDonald Voet
q q q
Judith G. Voet
q Charlotte W. Pratt
q q q
,Thisqpageqisqintentionallyqleftqblank
,STUDENT COMPANION TO ACCOMPANY q q q
FUNDAMENTALS OF q
BIOCHEMISTRY
LIFE AT THE MOLECULAR LEVEL
q q q q
Fourth Edition q
Akif Uzman
q
University of Houston q q
Jerry Johnson
q
University of Houston q q
Joseph Eichberg q
University of Houston q q
William Widger q
University of Houston q q
Donald Voet q
University of Pennsylvania q q
Judith G. Voet q q
Swarthmore College q
Charlotte W. Pratt q q
Seattle, Washington q
JOHNqWILEYq&qSONS,qINC
, CoverqDesignerqMadelynqLesureqCo
verqIllustrationqNormqChristiansenqC
overqPhotos
(VitruvianqMan):q©qOdysseus/Alamyqandq©qDennisqHallinan/Alamy
Molecularqstructuresqclockwiseqfromqtop:qbasedqonqX-
rayqstructuresqthatqwereqrespectivelyqdeterminedqbyqRichardqDickersonqandqHoraceqDrew,qCaltech;qGer
ardqBunick,qUniversityqofqTennessee;qThomasqSteitz,qYaleqUniversity;qAlfonsoqMondragón,qNorthwest
ernqUniversity;qVenkiqRamakrishnan,qMRCqLaboratoryqofqMolecularqBiology,qCambridge,qU.K.;qAndr
ewqLeslieqandqJohnqWalker,qMRCqLaboratoryqofqMolecularqBiology,qCambridge,qU.K.
Foundedqinq1807,qJohnqWileyq&qSons,qInc.qhasqbeenqaqvaluedqsourceqofqknowledgeqandqunderstandingqfor
qmoreqthanq200qyears,qhelpingqpeopleqaroundqtheqworldqmeetqtheirqneedsqandqfulfillqtheirqaspirations.qOurq
companyqisqbuiltqonqaqfoundationqofqprinciplesqthatqincludeqresponsibilityqtoqtheqcommunitiesqweqserveqan
dqwhereqweqliveqandqwork.qInq2008,qweqlaunchedqaqCorporateqCitizenshipqInitiative,qaqglobalqeffortqtoqaddr
essqtheqenvironmental,qsocial,qeconomic,qandqethicalqchallengesqweqfaceqinqourqbusiness.qAmongqtheqissue
sqweqareqaddressingqareqcarbonqimpact,qpaperqspecificationsqandqprocurement,qethicalqconductqwithinqourq
businessqandqamongqourqvendors,qandqcommunityqandqcharitableqsupport.qForqmoreqinformation,qpleaseqv
isitqourqwebsite:qwww.wiley.com/go/citizenship.
Copyrightq©q2012 JohnqWileyq&qSons,qInc.
Allqrightsqreserved.qNoqpartqofqthisqpublicationqmayqbeqreproduced,qstoredqinqaqretrievalqsystemqorqtrans
mittedqinqanyqformqorqbyqanyqmeans,qelectronic,qmechanical,qphotocopying,qrecording,qscanningqorqother
wise,qexceptqasqpermittedqunderqSectionsq107qorq108qofqtheq1976qUnitedqStatesqCopyrightqAct,qwithoutqe
itherqtheqpriorqwrittenqpermissionqofqtheqPublisher,qorqauthorizationqthroughqpaymentqofqtheqappropriateq
per-
copyqfeeqtoqtheqCopyrightqClearanceqCenter,qInc.,q222qRosewoodqDrive,qDanvers,qMAq01923,qwebsiteqw
ww.copyright.com.qRequestsqtoqtheqPublisherqforqpermissionqshouldqbeqaddressedqtoqtheqPermissionsqDe
partment,qJohnqWileyq&qSons,qInc.q111qRiverqStreet,qHoboken,qNJq07030-5774,q(201)q748-
6011,qfaxq(201)q748-6008,qwebsiteqhttp://www.wiley.com/go/permissions.
Toqorderqbooksqorqforqcustomerqservice,qpleaseqcallq1-800-CALLqWILEYq(225-5945).
StudentqCompanionq(paperback) ISBN-13q 978-1-1182-1827-3
PrintedqinqtheqUnitedqStatesqofqAmeric
aq10q 9q8q7q 6q5q4q 3q2q1
