Bps 319 - Lecture 4 Routes Of Drug
Administration Questions With Correct
Answers
rectal suppositories
vaginal suppositories, rings
Local drug administration direct application of drug to its site of action
Application of novocain to product local anesthesia
Treatment of ulcerative colitis with oral sulfasalazine
Inhalation of steroids and beta agonists to treat asthma Examples of local drug
administration
Systemic Drug Administration use of the systemic circulation to deliver drugs to their site
of action
ulcerative colitis (UC) inflammatory bowel disease
Parenteral Drug Administration includes all non-oral routes
- limited to injectables in pharmaceutics
, outside the GI tract What does parenteral mean?
sterility of the drug should be maintained
only skilled people should administer What are some things to keep in mind during
parenteral drug administration?
intravascular IV is most common but sometimes intraarterial is used
-used for immediate effect
-the whole of the dose is absorbed
extravascular any route that is not intravascular
e.g. oral, intramuscular, subcutaneous, transdermal, intranasal, pulmonary etc
True T or F: In extracellular drug administration, it is not guaranteed that the whole of the
drug will be absorbed
Bioavailability (F) The fraction of administered dose of a drug that reaches systemic
circulation
-a constant for a particular formulation of a drug
Bioequivalence A characteristic of two drugs in which all pharmacological and
physiological effects are identical
Administration Questions With Correct
Answers
rectal suppositories
vaginal suppositories, rings
Local drug administration direct application of drug to its site of action
Application of novocain to product local anesthesia
Treatment of ulcerative colitis with oral sulfasalazine
Inhalation of steroids and beta agonists to treat asthma Examples of local drug
administration
Systemic Drug Administration use of the systemic circulation to deliver drugs to their site
of action
ulcerative colitis (UC) inflammatory bowel disease
Parenteral Drug Administration includes all non-oral routes
- limited to injectables in pharmaceutics
, outside the GI tract What does parenteral mean?
sterility of the drug should be maintained
only skilled people should administer What are some things to keep in mind during
parenteral drug administration?
intravascular IV is most common but sometimes intraarterial is used
-used for immediate effect
-the whole of the dose is absorbed
extravascular any route that is not intravascular
e.g. oral, intramuscular, subcutaneous, transdermal, intranasal, pulmonary etc
True T or F: In extracellular drug administration, it is not guaranteed that the whole of the
drug will be absorbed
Bioavailability (F) The fraction of administered dose of a drug that reaches systemic
circulation
-a constant for a particular formulation of a drug
Bioequivalence A characteristic of two drugs in which all pharmacological and
physiological effects are identical
