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MIP 616 Cytoskeleton with 100- correct answers already graded A+(VERIFIED & UPDATED).

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MIP 616 Cytoskeleton with 100- correct answers already graded A+(VERIFIED & UPDATED).

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February 7, 2025
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MIP 616 Cytoskeleton
with 100% correct
answers already
graded A+(VERIFIED &
UPDATED)
The cytoskeleton is composed of what three filamentous structures? -
answer microfilaments, microtubules, and intermediate filaments


In fluorescent binding, which type of fluorescent is used for
microfilaments, microtubules and intermediate filaments? - answer
Microfilaments: phalloidin
Microtubules: anti-tubulin antibodies
Intermediate filaments: anti-kerarin bodies


Components of the cytoskeleton: ___________ and _____________ are dynamic;
they constantly grow and fall apart. ______________ are stable. - answer Actin
Microfilaments and Tubulin microtubules are dynamic; they grow and fall
apart. Intermediate filaments are stable.


Actin microfilaments, tubulin microtubules and intermediate filaments can
be labeled with specific fluorescent antibodies for ___________________________.
- answer Immunofluorescence microscopy assay (IFA).


Which cytoskeletal systems act as tracks for the movement of other
polymers? - answer microfilaments provide tracks for myosins.
Microtubules provide tracks for kinesins and dyneins.

, True or false: Intermediate filaments have motors to help other polymers
move through the cytoplasm. - answer False: intermediate filaments are
the only cytoskeleton system that does not have motors.


Microfilaments bind ________. - answer The actin in microfilaments binds
ATP


Microtubules bind ________. - answer tubulin in microtubules binds GTP


Which type of cytoskeleton component makes up the microvilli of
epithelial cells? - answer microfilaments


A white blood cell macrophage uses what at its leading edge for
movement? - answer Microfilaments


Actin is ____________ and abundant in cells. - answer highly conserved. Actin
from amoebae and animals are identical at 80 percent of their amino acid
positions despite a billion years of evolution.
Actin structure is critical to survival; It can't be changed;
it is "conserved".
Actins comprise 10 percent of the total protein in muscle cells.


What is G-actin and F-actin? - answer G-actin (Globular actin) reversibly
assembles into polarized F-actin (Filamentous actin)


____-_______ are structures that have two lobes and four subdomains and
make up F-actin. - answer G-actin.


G-actin has a ____-____________ cleft. - answer ATP-binding


F-actin binds to ATP and the _________ end. - answer Negative

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