Mechanism of
Concerns
Action S/E & Adverse Nursing Considerations
Class Prototype Drugs Contraindications
Therapeutic Use Reactions & Pt. Education
Food/Drug Interactions
Pharmacokinetics
Take 1x a day to take in
the morning.
MA: acts in the thick If taking 2x a day take at
Drugs: aspirin,
segment of the 8am & 2pm.
antibiotics, digoxin,
ascending limb of Administer w/ food if GI
diuretics, laxatives,
Henle loop to block upset occurs.
lithium, antihypertensives,
the reabsorption of Allergic reactions Treatment increases fluid
Furosemide methotrexate, NSAIDs,
Na & Cl (prevents Dehydration volume & frequency of
(PO, IV & IM) phenytoin, steroids,
passive reabsorption Hearing loss/tinnitus voiding, will subside 6-
[Lasix] thyroid hormones &
of water). Hyperglycemia 8hrs after dosing.
sucralfate.
Low BP Maintain weight record &
Torsemide
TR: HTN, reduce Hypokalemia report excessive gain/loss.
Loop Diuretics (PO & IV) Food: alcohol
swelling r/t heart, Burning/tingling Monitor BP
[Demadex]
kidney, or liver sensation in hand/feet Possible hearing loss,
Contraindications: D/V,
disease. Helps C/D notify if occurs.
Bumetanide gout, heart disease,
kidneys remove fluid Dizziness Monitor blood glucose
(PO, IV & IM) high/low electrolyte
& salt from blood Headache If dose is missed, do not
[Bumex] levels, kidney disease,
through urine. double or take extra.
liver disease, thyroid
May need special diet
disease, if allergic,
PK: PO, IV & IM Do not drive
pregnant/trying &
(IV used in critical Avoid alcohol
breastfeeding.
situations). Increases sensitivity to
sun (no tanning
beds/excessive sunlight).
, Module 5 - Cardiac & Diuretics 2
Mechanism of
Concerns
Action S/E & Adverse Nursing Considerations
Class Prototype Drugs Contraindications
Therapeutic Use Reactions & Pt. Education
Food/Drug Interactions
Pharmacokinetics
Allergic reactions
Take 1x a day to take in
MA: promotes urine Dehydration
the morning.
production by Gout
Drugs: MAOIs, If taking 2x a day take at
blocking the Kidney injury
barbiturates, lithium, BP 8am & 2pm.
reabsorption of Na & Hypotension
meds, narcotics, NSAIDs, Take with/out food
Cl in early segment Hypokalemia
steroids, digoxin, diuretics Store at room temp.
of distal convoluted Eye pain/vision
& diabetes meds. Protect from sunlight
tubule. changes
If dose is missed, do not
Hydrochlorothiazide Headache
Food: alcohol double or take extra.
Thiazide Diuretics (HCTZ) TR: HTN & Upset stomach
Do not self-treat for
[Microzide] swelling r/t heart, Hyponatremia
Contraindications: coughs, colds, or pain.
kidney or liver Hypochloremia
diabetes, gout, kidney Do not drive
disease. Helps Hyperglycemia
disease, liver disease, Do not sit/stand quickly.
kidneys remove fluid Hyperuricemia
lupus, pancreatitis, if Avoid alcohol
& salt from blood Reduction of HDL
allergic, pregnant/trying & Increases sensitivity to
into urine. cholesterol
breastfeeding. sun
Increase of LDL
May need special diet
PK: PO & IV cholesterol &
triglycerides