ABRAM’S CLINICAL DRUG THERAPY RATIONALES FOR
NURSING PRACTICE 13th EDITION GERALYN FRANDSEN’S
TESTBANK/COMPLETE GUIDE 2024-2025/ALL CHAPTERS 1-61
,Chapter 1: The Foundation of Pharmacology: Quality and Safety
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1. A patient diagnosed with obsessive–
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compulsive disorder has been prescribed oralparoxetine hydrochloride. What is t
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he expected effect for this prescription?
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A. Curative effect on symptoms RF RF RF
B. Systemic effect on symptoms RF RF RF
C. Local effect on symptoms RF RF RF
D. Parenteral effect on symptoms RF RF RF
ACCURATE ANSWER:-B RF
REASONING:-
>>>Pharmaceutical drug that produce systemic effects are taken into the body, circulated RF RF RF RF RF RF RF RF RF RF RF RF
through the bloodstream to their sites of action in various body tissues, and eventually eli
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minated from the body. Curative agents are given to cure a disease process. Inthis case, par
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oxetine hydrochloride will control the symptoms but not cure the disorder.
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Pharmaceutical drug with local effects, such as sunscreen and local anesthetics, act mainly a RF RF RF RF RF RF RF RF RF RF RF RF RF
t the siteof application. Paroxetine hydrochloride is not administered parenterally. Parente
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ral agentsare administered subcutaneously, intramuscularly, or intravenously.
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POINTS: 1 REFERENCE: p. 3, Introduction OBJ: RF RF 1
NAT: Hospital client Needs: Physiological Integrity: Pharmacological and Parenteral
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TherapiesTOP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety
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KEY: Integrated Process: Nursing Process
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BLM: Cognitive Level: Understand R F NOT: Multiple Choice RF RF R F RF
2. A hospital client has been prescribed an antibiotic. This pharmaceutical drug is a
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naturally occurringsubstance that has been cheGmRicAalDlyEm
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r name for this type of pharmaceutical drug?
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A. Synthetic drug RF
B. Semisynthetic drug RF
C. Biotechnology drug RF
D. Prototype drug RF
ACCURATE ANSWER:-B RF
REASONING:-
>>>Semisynthetic pharmaceutical drug (e.g., many antibiotics) are naturally occurring s RF RF RF RF RF RF RF RF RF
ubstances that have been chemically modified. Synthetic pharmaceutical drug are more st
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andardized in their chemical characteristics, more consistent in their effects, and less likel
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y to produce allergic reactions. Biotechnology pharmaceutical drug involve manipulating
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DNAand RNA and recombining genes into hybrid molecules that can be inserted into livi
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ng organisms. Prototype pharmaceutical drug are the first drug of a particular group to be
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developed.
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POINTS: 1 REFERENCE: p. 3, Drug Sources OBJ: RF RF RF 1
NAT: Hospital client Needs: Physiological Integrity: Pharmacological and Parenteral
RF RF RF RF RF RF RF RF RF
TherapiesTOP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety
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KEY: Integrated Process: Nursing Process
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BLM: Cognitive Level: Understand R F NOT: Multiple Choice RF RF R F RF
3. Which classification applies to morphine?
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A. Central nervous system depressant RF RF RF
B. Central nervous system stimulant RF RF RF
, C. Anti-inflammatory
D. Antihypertensive
ACCURATE ANSWER:-A RF
REASONING:-
>>>Pharmaceutical drug are classified according to their effects on particular body system RF RF RF RF RF RF RF RF RF RF RF
s, their therapeutic uses, and their chemical characteristics. Morphine is classified as a centr
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al nervous system depressant and will produce this effect in the hospital client. Acentral ner
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vous system stimulant increases attention and raises mood. An anti-
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inflammatoryagent decreases inflammation at the site of tissue or joint inflammation. An ant
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ihypertensiveagent reduces blood pressure. F
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POINTS: 1 REFERENCE:
p. 3, Drug Classifications and PrototypesOBJ:
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NAT: Hospital client Needs: Physiological Integrity: Pharmacological and Parenteral
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TherapiesTOP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety
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KEY: Integrated Process: Nursing Process
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BLM: Cognitive Level: Remember
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4. A hospital client is administered amoxicillin. The generic name of this pharmaceutical dru
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g belongs to whichdrug group?
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A. Selective serotonin reuptake inhibitors RF RF RF
B. Diuretics
C. Penicillins
D. ACE inhibitors RF
ACCURATE ANSWER:-C RF
REASONING:->>>The generic name GRADESBOOST.CO
often indicates the drug group (e.g., pharmaceutical drug RF RF RF RF RF RF RF RF RF RF
with generic names ending in “cillin” are penicillins). Selective serotonin reuptakeinhib
RF RF RF RF RF RF RF RF RF RF F
R
itors are pharmaceutical drugs
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that have antidepressant effects; SSRI is a broad classification, not a generic name. Diureticsa
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re pharmaceutical drugs that increase urine output; diuretic is a broad classification, not a g
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eneric name. ACE inhibitor is the broad classification for the angiotensin receptor blockers,
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not thegeneric name.
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POINTS: 1 REFERENCE: p. 3, Drug Names OBJ: RF RF RF 2
NAT: Hospital client Needs: Physiological Integrity: Pharmacological and Parenteral
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TherapiesTOP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety
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KEY: Integrated Process: Nursing Process
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BLM: Cognitive Level: Understand
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5. The administration of diphenhydramine is regulated by which U.S. government agency?
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A. Public Health Service RF RF
B. Federal Trade Commission RF RF
C. Occupational Safety and Health Administration RF RF RF RF
D. Food and Dru RF RF
gAdministration
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ACCURATE ANSWER:-D RF
, REASONING:-
>>>The Food and Drug Administration approves pharmaceutical drug for over- the-
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counter availability, including the transfer of pharmaceutical drug from prescription to O
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TC status, and may require clinical trials to determine the safety and effectiveness of OTC
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use.The Public Health Service is regulated by the state to maintain the health of individua
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l citizens of the state. The Federal Trade Commission regulates imports and exports thro
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ughout the nation. The Occupational Safety and Health Administration regulates safetywit
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hin the workplace. RF RF
POINTS: 1 REFERENCE: p. 4, Prescription and Nonprescription RF RF RF RF
Pharmaceutical drug OBJ: 4 RF RF
NAT: Hospital client Needs: Physiological Integrity: Pharmacological and Parenteral
RF RF RF RF RF RF RF RF RF
TherapiesTOP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety
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KEY: Integrated Process: Nursing Process
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BLM: Cognitive Level: Understand R F NOT: Multiple Choice RF RF R F RF
6. In the U.S., the administration of anabolic steroids is regulated by which law?
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A. The Food, Drug, and Cosmetic Act of 1938 RF RF RF RF RF RF RF
B. The Comprehensive Drug Abuse Prevention and Control Act
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C. The Harrison Narcotic Act RF RF RF
D. The Sherley Amendment RF RF
ACCURATE ANSWER:-B RF
REASONING:-
>>>The Comprehensive Drug Abuse Prevention and Control Act regulates the manufact
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ure and distribution of narcotics, stimulants, depressants, hallucinogens, and anabolic stero
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ids. The Food, Drug, and Cosmetic Act of 1938 revised and broadened FDA powers and res
RF RF RF RF RF RF RF RF RF RF RF RF RF RF RF
ponsibilities, giving the FDA control over drug safety. The Harrison Narcotic Act restricted
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the importation, manufacture, sale, and use of opium,cocaine, marijuana, and other pharmaceu
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ticaldrugthat the act d e fi GneRd AaDs E
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tiO
csS
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erley Amendment of 1912 prohibited fr
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audulent claims of drug effectiveness. RF RF RF RF
POINTS: 1 REFERENCE: p. 4, Prescription and Nonprescription RF RF RF RF
Pharmaceutical drug OBJ: 3 RF RF
NAT: Hospital client Needs: Physiological Integrity: Pharmacological and Parenteral
RF RF RF RF RF RF RF RF RF
TherapiesTOP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety
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KEY: Integrated Process: Nursing Process
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BLM: Cognitive Level: Remember R F NOT: Multiple Choice RF RF R F RF
7. A nursing attendant is responsible for maintaining an accurate count and record of the
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controlled substances on the nursing division. This nursing action is regulated by whic
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h
U.S. law or agency? RF RF RF
A. The Food, Drug, and Cosmetic Act of 1938 RF RF RF RF RF RF RF
B. The Public Health Service RF RF RF
C. The Drug Enforcement Administration RF RF RF
D. The Sherley Amendment RF RF F
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ACCURATE ANSWER:-C RF
NURSING PRACTICE 13th EDITION GERALYN FRANDSEN’S
TESTBANK/COMPLETE GUIDE 2024-2025/ALL CHAPTERS 1-61
,Chapter 1: The Foundation of Pharmacology: Quality and Safety
RF RF RF RF RF RF RF RF
1. A patient diagnosed with obsessive–
RF RF RF RF
compulsive disorder has been prescribed oralparoxetine hydrochloride. What is t
RF RF RF RF RF F
R RF RF RF RF
he expected effect for this prescription?
RF RF RF RF RF
A. Curative effect on symptoms RF RF RF
B. Systemic effect on symptoms RF RF RF
C. Local effect on symptoms RF RF RF
D. Parenteral effect on symptoms RF RF RF
ACCURATE ANSWER:-B RF
REASONING:-
>>>Pharmaceutical drug that produce systemic effects are taken into the body, circulated RF RF RF RF RF RF RF RF RF RF RF RF
through the bloodstream to their sites of action in various body tissues, and eventually eli
RF RF RF RF RF RF RF RF RF RF RF RF RF RF
minated from the body. Curative agents are given to cure a disease process. Inthis case, par
RF RF RF RF RF RF RF RF RF RF RF RF RF F
R RF RF
oxetine hydrochloride will control the symptoms but not cure the disorder.
RF RF RF RF RF RF RF RF RF RF
Pharmaceutical drug with local effects, such as sunscreen and local anesthetics, act mainly a RF RF RF RF RF RF RF RF RF RF RF RF RF
t the siteof application. Paroxetine hydrochloride is not administered parenterally. Parente
RF RF F
R RF RF RF RF RF RF RF RF
ral agentsare administered subcutaneously, intramuscularly, or intravenously.
RF F
R RF RF RF RF RF
POINTS: 1 REFERENCE: p. 3, Introduction OBJ: RF RF 1
NAT: Hospital client Needs: Physiological Integrity: Pharmacological and Parenteral
RF RF RF RF RF RF RF RF RF
TherapiesTOP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety
F
R RF RF RF RF RF RF RF RF
KEY: Integrated Process: Nursing Process
R F RF RF RF
BLM: Cognitive Level: Understand R F NOT: Multiple Choice RF RF R F RF
2. A hospital client has been prescribed an antibiotic. This pharmaceutical drug is a
RF RF RF RF RF RF RF RF RF RF RF RF RF
naturally occurringsubstance that has been cheGmRicAalDlyEm
RF
SoBdOifOieSd.TWhaOt Mi s anothe
.C F
R RF RF RF RF RF RF R
F RF R
F
r name for this type of pharmaceutical drug?
RF RF RF RF RF RF RF
A. Synthetic drug RF
B. Semisynthetic drug RF
C. Biotechnology drug RF
D. Prototype drug RF
ACCURATE ANSWER:-B RF
REASONING:-
>>>Semisynthetic pharmaceutical drug (e.g., many antibiotics) are naturally occurring s RF RF RF RF RF RF RF RF RF
ubstances that have been chemically modified. Synthetic pharmaceutical drug are more st
RF RF RF RF RF RF RF RF RF RF RF
andardized in their chemical characteristics, more consistent in their effects, and less likel
RF RF RF RF RF RF RF RF RF RF RF RF
y to produce allergic reactions. Biotechnology pharmaceutical drug involve manipulating
RF RF RF RF RF RF RF RF RF RF
DNAand RNA and recombining genes into hybrid molecules that can be inserted into livi
F
R RF RF RF RF RF RF RF RF RF RF RF RF RF
ng organisms. Prototype pharmaceutical drug are the first drug of a particular group to be
RF RF RF RF RF RF RF RF RF RF RF RF RF RF R
developed.
F
POINTS: 1 REFERENCE: p. 3, Drug Sources OBJ: RF RF RF 1
NAT: Hospital client Needs: Physiological Integrity: Pharmacological and Parenteral
RF RF RF RF RF RF RF RF RF
TherapiesTOP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety
F
R RF RF RF RF RF RF RF RF
KEY: Integrated Process: Nursing Process
R F RF RF RF
BLM: Cognitive Level: Understand R F NOT: Multiple Choice RF RF R F RF
3. Which classification applies to morphine?
RF RF RF RF
A. Central nervous system depressant RF RF RF
B. Central nervous system stimulant RF RF RF
, C. Anti-inflammatory
D. Antihypertensive
ACCURATE ANSWER:-A RF
REASONING:-
>>>Pharmaceutical drug are classified according to their effects on particular body system RF RF RF RF RF RF RF RF RF RF RF
s, their therapeutic uses, and their chemical characteristics. Morphine is classified as a centr
RF RF RF RF RF RF RF RF RF RF RF RF RF
al nervous system depressant and will produce this effect in the hospital client. Acentral ner
RF RF RF RF RF RF RF RF RF RF RF RF RF F
R RF
vous system stimulant increases attention and raises mood. An anti-
RF RF RF RF RF RF RF RF RF
inflammatoryagent decreases inflammation at the site of tissue or joint inflammation. An ant
F
R RF RF RF RF RF RF RF RF RF RF RF RF
ihypertensiveagent reduces blood pressure. F
R RF RF RF
POINTS: 1 REFERENCE:
p. 3, Drug Classifications and PrototypesOBJ:
RF 1 RF RF RF RF F
R
NAT: Hospital client Needs: Physiological Integrity: Pharmacological and Parenteral
RF RF RF RF RF RF RF RF RF
TherapiesTOP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety
F
R RF RF RF RF RF RF RF RF
KEY: Integrated Process: Nursing Process
R F RF RF RF
BLM: Cognitive Level: Remember
R F NOT: Multiple Choice RF RF R F RF
4. A hospital client is administered amoxicillin. The generic name of this pharmaceutical dru
RF RF RF RF RF RF RF RF RF RF RF RF
g belongs to whichdrug group?
RF RF RF F
R RF
A. Selective serotonin reuptake inhibitors RF RF RF
B. Diuretics
C. Penicillins
D. ACE inhibitors RF
ACCURATE ANSWER:-C RF
REASONING:->>>The generic name GRADESBOOST.CO
often indicates the drug group (e.g., pharmaceutical drug RF RF RF RF RF RF RF RF RF RF
with generic names ending in “cillin” are penicillins). Selective serotonin reuptakeinhib
RF RF RF RF RF RF RF RF RF RF F
R
itors are pharmaceutical drugs
RF RF RF
that have antidepressant effects; SSRI is a broad classification, not a generic name. Diureticsa
RF RF RF RF RF RF RF RF RF RF RF RF RF F
R
re pharmaceutical drugs that increase urine output; diuretic is a broad classification, not a g
RF RF RF RF RF RF RF RF RF RF RF RF RF RF
eneric name. ACE inhibitor is the broad classification for the angiotensin receptor blockers,
RF RF RF RF RF RF RF RF RF RF RF RF RF
not thegeneric name.
RF F
R RF
POINTS: 1 REFERENCE: p. 3, Drug Names OBJ: RF RF RF 2
NAT: Hospital client Needs: Physiological Integrity: Pharmacological and Parenteral
RF RF RF RF RF RF RF RF RF
TherapiesTOP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety
F
R RF RF RF RF RF RF RF RF
KEY: Integrated Process: Nursing Process
R F RF RF RF
BLM: Cognitive Level: Understand
R F NOT: Multiple Choice RF RF R F RF
5. The administration of diphenhydramine is regulated by which U.S. government agency?
RF RF RF RF RF RF RF RF RF RF
A. Public Health Service RF RF
B. Federal Trade Commission RF RF
C. Occupational Safety and Health Administration RF RF RF RF
D. Food and Dru RF RF
gAdministration
F
R
ACCURATE ANSWER:-D RF
, REASONING:-
>>>The Food and Drug Administration approves pharmaceutical drug for over- the-
RF RF RF RF RF RF RF RF RF RF
counter availability, including the transfer of pharmaceutical drug from prescription to O
RF RF RF RF RF RF RF RF RF RF RF
TC status, and may require clinical trials to determine the safety and effectiveness of OTC
RF RF RF RF RF RF RF RF RF RF RF RF RF RF RF
use.The Public Health Service is regulated by the state to maintain the health of individua
F
R RF RF RF RF RF RF RF RF RF RF RF RF RF RF
l citizens of the state. The Federal Trade Commission regulates imports and exports thro
RF RF RF RF RF RF RF RF RF RF RF RF RF
ughout the nation. The Occupational Safety and Health Administration regulates safetywit
RF RF RF RF RF RF RF RF RF RF F
R
hin the workplace. RF RF
POINTS: 1 REFERENCE: p. 4, Prescription and Nonprescription RF RF RF RF
Pharmaceutical drug OBJ: 4 RF RF
NAT: Hospital client Needs: Physiological Integrity: Pharmacological and Parenteral
RF RF RF RF RF RF RF RF RF
TherapiesTOP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety
F
R RF RF RF RF RF RF RF RF
KEY: Integrated Process: Nursing Process
R F RF RF RF
BLM: Cognitive Level: Understand R F NOT: Multiple Choice RF RF R F RF
6. In the U.S., the administration of anabolic steroids is regulated by which law?
RF RF RF RF RF RF RF RF RF RF R
F RF
A. The Food, Drug, and Cosmetic Act of 1938 RF RF RF RF RF RF RF
B. The Comprehensive Drug Abuse Prevention and Control Act
RF RF RF RF RF RF RF
C. The Harrison Narcotic Act RF RF RF
D. The Sherley Amendment RF RF
ACCURATE ANSWER:-B RF
REASONING:-
>>>The Comprehensive Drug Abuse Prevention and Control Act regulates the manufact
RF RF RF RF RF RF RF RF RF RF
ure and distribution of narcotics, stimulants, depressants, hallucinogens, and anabolic stero
RF RF RF RF RF RF RF RF RF RF
ids. The Food, Drug, and Cosmetic Act of 1938 revised and broadened FDA powers and res
RF RF RF RF RF RF RF RF RF RF RF RF RF RF RF
ponsibilities, giving the FDA control over drug safety. The Harrison Narcotic Act restricted
RF RF RF RF RF RF RF RF RF RF RF RF RF
the importation, manufacture, sale, and use of opium,cocaine, marijuana, and other pharmaceu
RF RF RF RF RF RF RF F
R RF RF RF RF
ticaldrugthat the act d e fi GneRd AaDs E
RF naSrcBoO
tiO
csS
F
R .TTh.eCSOhM
erley Amendment of 1912 prohibited fr
RF RF RF F
R RF F
R F
R R F RF RF RF R
F RF RF
audulent claims of drug effectiveness. RF RF RF RF
POINTS: 1 REFERENCE: p. 4, Prescription and Nonprescription RF RF RF RF
Pharmaceutical drug OBJ: 3 RF RF
NAT: Hospital client Needs: Physiological Integrity: Pharmacological and Parenteral
RF RF RF RF RF RF RF RF RF
TherapiesTOP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety
F
R RF RF RF RF RF RF RF RF
KEY: Integrated Process: Nursing Process
R F RF RF RF
BLM: Cognitive Level: Remember R F NOT: Multiple Choice RF RF R F RF
7. A nursing attendant is responsible for maintaining an accurate count and record of the
RF RF RF RF RF RF RF RF RF RF RF RF RF R
controlled substances on the nursing division. This nursing action is regulated by whic
F RF RF RF RF RF RF RF RF RF RF RF RF
h
U.S. law or agency? RF RF RF
A. The Food, Drug, and Cosmetic Act of 1938 RF RF RF RF RF RF RF
B. The Public Health Service RF RF RF
C. The Drug Enforcement Administration RF RF RF
D. The Sherley Amendment RF RF F
R
ACCURATE ANSWER:-C RF
